Izifo ze-Celiac noma ukuzwela kwe-gluten kungabangela umonakalo wesibindi
Uke wavumela unyawo lwakho ukuba lulale futhi luqale lube yingxenyeni bese luvela ekugumbeni, izikhonkwane-nezinaliti ukuzwa ngenkathi "kuvuswa"? Abantu abane-neuropathy ye-peripheral bahlushwa yizo zinhlobo zokuzizwa - ukungenwa kwesibindi nokuhlukumeza okubuhlungu - sonke isikhathi. Futhi kukhona ubufakazi obukhulayo bokuthi i-peripheral neuropathy ixhunywe nesifo se-celiac nokuzwela kwe-gluten.
Abantu abangaba ngu-10% abasanda kutholakala ukuthi banezifo ze- celiac bahlupheka ngesimo sezinzwa ezihambisanayo , ngokuvamile kutholakala nge-neuropathy (okuyinto evamile) noma i- gluten ataxia (okuyiyona ejwayelekile), izifundo zibonisa.
Okwamanje, ukuzwela kwe-gluten okungewona i-celiac yisimiso esanda kuqashelwa esingavunyelwanga emhlabeni wonke, futhi akuzange kube khona izifundo ezibheke ekubhekaneni kwe-neuropathy njengempilo yezokwelapha ehambisana nayo. Kodwa-ke, odokotela abenza ucwaningo ngalesi sihloko bathi ukugubha kanye nokuphazamiseka emaphethelweni kumelela enye yezimpawu ezivame kakhulu zokuvuthwa kwe-gluten .
I-Peripheral Neuropathy ihlanganisa Ukulimala Kwemigodi
Ukuxubha, ukuphazamiseka, nobuhlungu be-peripheral neuropathy ngokuvamile kubangelwa ukulimala kwamagciwane ezandleni nasezinyaweni zakho. Ukulimala kwamagciwane - futhi izimpawu - ngokuvamile ziqala emithanjeni yakho ende, yingakho uzobona izimpawu kuqala ezinyaweni zakho futhi mhlawumbe ngezandla zakho.
Ukuzizwa okunempilo (ngezinye izikhathi izinyawo noma izandla zakho zingazizwa zibandayo, noma zishisa, noma zifana nokuzibamba komuntu ngomculo okhaliphile) ngokuvamile ziqala ekude kakhulu futhi zisebenze ngaphakathi, uphakamise imilenze yakho kanye nezingalo zakho. Ungaba nesisindo esisodwa esisithintekile noma izinzwa eziningi.
Isifo sikashukela singumbuzo owodwa we-peripheral neuropathy kusukela kwaze kwafika kwaba yingxenye yabo bonke abashukela ngesifo sikashukela bazobhekana nomonakalo wezinzwa.
Noma kunjalo, izimo ezizimele (isifo se-celiac sisebenza ngokwemvelo) nazo ziye zaxhunyaniswa ne-peripheral neuropathy.
I-Peripheral Neuropathy I-Gluten-Ehlobene Nezinye Izimo
Kwezinye izimo, i-peripheral neuropathy ibonakala ihlobene nokusetshenziswa kwe-gluten - ngokuqondile, kuma-antibodies anti-gluten abanye abantu abakhiqiza ekuphenduleni ukusetshenziswa kwe-gluten.
Esinye isifundo, abacwaningi bahlola iziguli ezingu-215 ezine-neonopal neuropathy, uhlobo lwe-peripheral neuropathy olubandakanya umonakalo kuma-axon akho, noma amazinyo ezinzwa. Ingqikithi eyi-140 yalezi zine "neuropathy," okusho ukuthi kwakungekho isizathu esibonakalayo sezokwelapha se-peripheral neuropathy.
Abacwaningi bahlolisisa abantu abangu-140 ukuba balwe namagciwane ukuze bahlolisise ukuhlolwa kwegazi le-celiac , ukuhlolwa kwe - AGA-IgA , kanye nokuhlolwa kwe- AGA-IgG . Nakuba lezi zivivinyo zingacatshangwa ukuthi ziqondile kakhulu kwisifo se-celiac, zingakwazi ukubona ukuthi umzimba wakho ubuka kanjani i-gluten njengesihlaseli futhi udala ama-antibodies ngokumelene neprotheyini.
Amaphesenti angu-38 alabo abahlolwe - abantu abangu-47 - babe nama-antibodies aphakeme ukuze bahlolisise kokubili noma kokubili kwalezi zivivinyo, uma kuqhathaniswa nesilinganiso se-12% sama-antibodies aphezulu ukuba agwebe kulo lonke labantu. Leyo miphumela yokuhlola ingabonisa ukuthi abantu babenokuzwela kwe-gluten ngoba abanye ochwepheshe batusa i-AGA-IgA kanye ne-AGA-IgG njengezivivinyo zokuzwela kwe-gluten .
Abacwaningi baphinde babone izigcawu ze-endoscopies kanye ne-biopsies kulabo bantu esifundweni okusolakala ukuthi banesifo se-celiac futhi bathola ukuthi abangu-9% kulabo "eqenjini elingaqondakali" le-nelipathy babe ne-celiac. Izifo zesifo se-celiac - okungukuthi, i- HLA-DQ2 ne- HLA-DQ8 - zitholakale ku-80% yazo zonke iziguli ze-neuropathy zenye.
I-Peripheral Neuropathy Isibonakaliso Esiyisici Sobuningi be-Celiac noGututen
I-neuropathy ye-peripheral empeleni ingenye yezimpawu ezingavamile zokugaya izifo zesifo se-celiac , ngokusho kwe-University of Chicago Celiac Disease Centre. Eqinisweni, kungenzeka ukuthi awubonakali izimpawu zomzimba zesifo se-celiac, kodwa kunalokho ukuba ikakhulukazi i-neuropathy yochungechunge nezinye izimpawu zezinzwa.
Izimpawu ze-neurological ezifana ne-peripheral neuropathy, i- migraine , ne- brain fog zivame ngokwengeziwe ekuzweleni kwe-gluten okungenayo i-celiac, kusho uDkt. Alessio Fasano, ongomunye wabacwaningi abaholayo emkhakheni wokuzwela kwe-gluten. UDkt. Fasano uthe abantu abangaba ngu-30% abathola ukuthi unomzwelo we-gluten unezimpawu zezinzwa ... iphesenti elikhulu kakhulu kunabantu abanezimpawu ze-neurolo kwisifo se-celiac.
Uma une-neuropathy ye-peripheral futhi uthola ukuthi une-celiac noma i-gluten ukuzwela, ungakwazi ukuthuthukisa noma ngisho nokuxazulula izimpawu zakho ngokulandela ukudla okungekho gluten - ezinye izifundo zithole ukudla kusiza. Kodwa-ke, ezinye izifundo ziye zathola ukuthi "ukubonakaliswa kwe-neurologic," kufaka phakathi i-peripheral neuropathy, kungase kuqhubekele noma kuthuthuke ngemuva kokuxilongwa, okubonisa ukuthi kungase kube khona inqubo yokuvuvukala ehambisanayo.
IYunivesithi yaseChicago itusa ukuthi abantu abane-neuropathy ye-peripheral abangenwe yisifo se-celiac baqiniseke ukuthi baxoxisana nodokotela babo mayelana nokuyeka izidakamizwa ezingase zidale i-peripheral neuropathy. Odokotela basekhaya babuye batusa ukuthi i-celiacs ne-peripheral neuropathy yenza ukushintsha kwendlela yokuphila kuguqule ukunciphisa ubuhlungu babo, kuhlanganise nokugwema isikhathi eside sokuma noma ukuhamba, ukugqoka izicathulo ezingavamile (kwezinye izimo, umshuwalense ungase uhlanganise izicathulo ezikhethekile zokwelashwa), futhi ugibele izinyawo ngamanzi e-ice ukuze unciphise ubuhlungu nokugubha.
Odokotela nabo bangakwazi ukunikeza imishanguzo enganciphisa ezinye zezinto eziphazamisayo ze-peripheral neuropathy, ikakhulukazi uma kungabonakali ukuphendula ekudleni okungenalutho kwe-gluten. Okwamanje, abantu abane-neuropathy ye-peripheral, noma ngabe kubonakala sengathi bahlobene nesifo se-celiac noma ukuzwela kwe-gluten, kufanele baqiniseke ukuthi baqaphele uma behamba noma behamba ngoba ukungabi nokho okuzwakalayo ezinyaweni zabo kungaholela engozini yokuwa .
Imithombo:
I-Chin R. et al. I-Peripheral Neuropathy Nezifo Ezibucayi. Izinketho zamanje zokwelashwa ku-Neurology. 2005 Jan; 7 (1): 43-48.
Hadjivassiliou M. et al. I-Neuropathy Ehambisana Ne-Gluten Ukuzwela. Journal of Neurology, Neurosurgery, kanye Psychiatry. 2006; Nov; 77 (11): 1262-6. Epub 2006 Jul 11.
URigamonti A. et al. Izifo Zama-Celiac ezethula nge-Motor Neuropathy: Imiphumela ye-Gluten-Free Diet. Imisipha & Nerve. 2007 Meyi; 35 (5): 675-7.
IYunivesithi yaseChicago Centre ye-Peripheral Neuropathy. Izinhlobo Zokuphazamiseka Kwegazi - Ukuvutha - Izifo Zama-Celiac.
I-Zelnik N. et al. Ububanzi Bezinkinga Ze-Neurologic Ezigulini Eziphethwe Izifo Ezibucayi. Izingane zokwelapha. 2004 Jun; 113 (6): 1672-6.