Ukunquma Ingozi Yokuthuthukiswa Kwesifo Se-Rheumatoid Arthritis
Ngenkathi kunezinhlobo eziningi ze-arthritis , iziguli azivumelani ngaso sonke isikhathi kwizigaba zesifo esisekelwe kahle nesaziwayo. Isiguli singase sibe sezinyathelo zokuqala zesifo samathambo , kodwa isibonelo sezimpawu asihambisani nolunye uhlobo lwe-arthritis. Kungase kube nezimpawu eziqhamukayo ezihambisana nesifo esingaphezu kwesisodwa se-rheumatic.
Uma isiguli sinemibonakalo ehambisana nesifo samathambo kodwa hhayi uhlobo oluthile, zihlukaniswa njengezifo ezinganqamuki. Yindlela yokusho ukuthi akukho ukuxilongwa okucacile okwamanje okungenziwa.
Kungani Ukubikezela Inkambo Ye-Arthritis Engabonakali Kubalulekile
Kulinganiselwa ukuthi iziguli ezingama-40-50% ezine-arthritis ezingenakunyakaziswa zithola ukuxolelwa okuzenzekelayo. Cishe abantu abangamaphesenti angama-30 abanesifo samathambo esingenakudliwa sakha i-arthritis ye- rheumatoid , kuyilapho bonke behlakulela ezinye izimo. Njengoba umgomo wokwelapha iziguli ezine-arthritis ye-rheumatoid ukuyeka ukuqhubeka kwesifo, kuyasiza ukuzama ukubikezela ukuthi iziphi iziguli ezine-arthritis ezingenakudliwa cishe zizokwakha isifo samathambo e-rheumatoid.
Ngo-2008, umthetho wokubikezela wasungulwa eYurophu futhi washicilelwa encwadini, i- Arthritis & Rheumatism . Ngokucatshangelwa okwenziwe isiguli sesiguli, ubulili, amanxeba amathintekayo, ukuqina kwesikhathi eside, i- CRP , i- rheumatoid factor , kanye ne-anti-CCP , ingozi yokuthuthukisa isifo samathambo i-arthritis ikwazi ukubikezela kakhulu ezigulini ezine-arthritis engafaneleki.
Ngo-2010, i-American College of Rheumatology yabambisana ne-European League Against Rheumatism ukuze ibuyekeze iziqondiso ezisetshenziselwa ukuxilonga i-rheumatoid arthritis. Iziqondiso ezibuyekeziwe zigxile ezinyathelweni zangaphambili zalesi sifo kunokuba izici zesigaba sekwephuzile ezihambisana nesifo samathambo esiqhubekayo noma esingahle siphumelele.
Ngokusho kwemihlahlandlela ebuyekeziwe, i-arthritis eqondile ye-rheumatoid isekelwe ebukhosini obuqinisekisiwe be- synovitis okungenani okuhlangene okukodwa, ukungabikho kwesinye ukuxilongwa okuchaza kangcono i-synovitis, nokuphumelela kwamaphuzu angama-6 noma ngaphezulu (angaphumi kuka-10) kusuka izibalo zomuntu ngamunye kulezi zihlolo ezilandelayo ezilandelayo: inombolo kanye nesayithi lamalungu angathintekayo (amaphuzu ebanga 0-5), ukungavamile kwe-serologic (isifo somzimba se-rheumatoid noma i-anti-CCP; ibanga lesikweletu 0-3), impendulo ephezulu ye-acute (i-CRP noma isilinganiso se-sedimentation ; ibanga lobubanzi 0-1), nobude besikhathi (amazinga amabili; u-0-1).
Ngenkathi ukuhlolwa kwe-radiographic (okungukuthi, ama-x-ray noma i-MRI), ikakhulukazi yezinguquko zezandla nezinyawo, ingahlinzeka ngolwazi olwengeziwe kumtholampilo, iyadla isikhathi futhi ingabi nengozi njengethuluzi lokuhlola ukubikezela ingozi yokuthuthukisa i-arthritis ye-rheumatoid ezigulini ezine-arthritis engafaneleki.
Ukuqhubeka kwe-arthritis ye-rheumatoid kufana neziguli eziqala ukutholakala ukuthi zine-arthritis engafanelekile kodwa ziqhubeke nokuthuthukisa isifo samathambo kanye nalabo abatholwa ukuthi bane-arthritis ye-rheumatoid ekuqaleni. Ukulahla ukwelashwa ngezidakamizwa eziguqula izifo eziphikisana nezifo noma izidakamizwa ze- biologic ezigulini ezine-arthritis engafaneleki kunganciphisa ukwelashwa okungalungile kweziguli ezizoqhubeka nokuthola ukuxolelwa okuzenzekelayo, kodwa ukwelashwa okuqala kunikeza ithuba elihle lokuvimbela ukuguquka kwezifo, ukukhubazeka, kanye nokunciphisa ikhwalithi yokuphila phakathi kwalabo abasengozini yokuthuthukisa isifo samathambo.
Yingakho ukubikezela ingozi kusiza ukukhetha iziguli okungenzeka akumele ziphuze ukwelashwa.
Kufanele Ukwelashwa Ukwelashwa?
Kube khona izifundo ezincane ezihlolisisa ukusetshenziswa kwezidakamizwa eziguqula izifo-anti-rheumatic noma ze-biologics ukuvimbela ukuqhubekela phambili kwe-arthritis engafaneleki kwi-arthritis ye-rheumatoid. Ngenkathi imiphumela iphakamisa ukuthi i- methotrexate ne- Orencia (abatacept) ivimbela ukuqhubekela phambili ku-arthritis ye-rheumatoid uma kuqhathaniswa ne-placebo, Remicade ayizange. Kudingeka izifundo ezinkulu.
Imithombo
2010 I-Rheumatoid I-Arthritis Classification Imigomo: I-American College of Rheumatology / i-European League Yokulwa neRheumatism Collaborative Initiative. U-Aletaha, uDaniel et al. I-arthritis ne-Rheumatism. Agasti 10, 2010.
Ukuvimbela Ukuqhubekela Emthonjeni We-Arthritis Engabonakaliyo Ku-Arthritis Ye-Rheumatoid: Imiphumela Yomtholampilo Nezomnotho. UMichael H. Schiff, MD. I-American Journal Yokuphathwa Okunakekelwe. Novemba 19, 2010.
Ukuqinisekiswa komthetho wokubikezela izifo ezibangelwa izifo ezigulini ezine-Arthritis. I-arthritis ne-Rheumatism. van der Helm-van Mil, AHM, et al. Umqulu 58, Issue 8. Agasti, 2008.