I-Angioedema ingaba yifa, kepha iningi lalo alikho. Kunezivivinyo zokuxilonga ezingakwazi ukubona i-angioedema yefa.
I-Angioedema engesiyo ifa ngokuvamile ixilongwa ngokususelwa ekubukeni kwesikhumba kuhlangene nomlando wokuchayeka kwento engase ibangele ukusabela okweqile. Ngezinye izikhathi, ukuhlolwa kwegazi kungase kusekele ukuxilongwa, kepha imiphumela ayifuni ngokuqondene nokungajwayelekile okuhambisanayo.
Ukuhlola Ukuhlola / Ukuhlolwa Kwekhaya
Ungahlola wena noma ingane yakho nge-angioedema. Ngokuvamile, izimpawu ozozihlola zibonakala ngokucacile ebusweni sesikhumba, ngakho akudingeki uzifune.
Izimpawu ongazihlola zifaka:
- Izindebe ezivuvukile
- Amehlo avuvukile
- Ukuvuvukala kwezingalo noma imilenze
- Ukuvuvukala kolimi lwakho noma ngemuva komphimbo wakho
- Ukuvuvukala okungalindelekile kunoma iyiphi ingxenye yomzimba
- Ukungcoliswa: Ukuvuvukala kwe-angioedema kubonakala ebusweni besikhumba futhi kubonakala kukhwabanisa. Ngokuvamile, kukhona umbala obomvu noma obomvu noma ukuqhuma.
- I-Blanching: Ukuhlukanisa okubomvu okwenzeka ngama-blanche angioedema. I-Blanching ichaza ukuthambekela kwesikhumba esithintekile ukuba sibe mbala ngamasekhondi ambalwa ngenkathi ucindezela kuyo bese ubuyela kumbala wayo obomvana noma obomvu.
Enye indlela yokuhlola ukuthi wena noma ingane yakho une-angioedema ukubuka uhlu lwezithako zokudla okulungiselelwe oye wadla, uma kuqukethe into ethile noma ilungu lomndeni osondelene nalo liye laphulukiswa esikhathini esedlule.
Ama-Labs nezivivinyo
Kunezinhlobo ezimbili eziyinhloko ze-angioedema-uhlobo oluthile lwefa kanye nenhlobo engeyona ifa. Izimpawu ziyafana, kodwa izivivinyo zokuxilonga eziqinisekisa uhlobo ngalunye zihlukile.
I-Angioedema Engeyona Eyodwa
Ngokuvamile, i-angioedema engasiyo ifa isifo sokuxilongwa esekelwe ekuhloleni kukadokotela wakho wezimpawu zakho, ukuhlolwa kwakho ngokomzimba, nokuhlonza i-allergen.
I-allergen iyisisulu esibangela ukuphendula kwamagciwane okuqinile.
Ukuhlolwa okujwayelekile okusetshenziselwa ukuhlolwa kwe-angioedema kubandakanya:
- Ukuvivinya umzimba: Kukhona izivivinyo ezihlukahlukene zokungezwani komzimba . Okuvame kakhulu kuhilela isikhumba esincane esikhwameni esincane sempahla esolwa ukuthi ibangela ukungezwani komzimba. Uma unezimpendulo ezinjengokubomvu, ukuqhuma, ukuvuvukala, noma ukushaya endaweni yomuntu oyimpumputhe, kungenzeka ukuthi unomdlavuza owenziwe yizifo. Ungase uhlolwe izinto eziningana ngezikhathi ezithile, futhi uma usabela komunye futhi hhayi kwabanye lokhu kuyisibonakaliso esinamandla sokungezwani komzimba.
- Ukuhlolwa kwegazi: Ukuhlolwa kwegazi kungathola amazinga aphezulu okusebenza kwe-immunological. Ezinye izibonakaliso zokwandisa umsebenzi we-immune zibandakanya amazinga asemhlophe egazi eliphakeme, i-erythrocyte sedimentation rate (ESR), ne-anti-nuclear antibody (ANA). Zonke lezi, noma kunjalo, zingabonakalisa izifo eziningana nezifo zokuzivikela, ngakho-ke azizona eziqondile kwi-angioedema.
Ngezinye izikhathi, akukho-allergen ekhonjisiwe futhi i-angioedema ingase ihlolwe ukukhishwa ngemva kwezinye izimbangela zezimpawu eziye zaqedwa.
I-Angeliedema ye-Hereditary
Ukuhlolwa kofuzo kanye nokuhlolwa kwegazi kungabonisa lesi simo. Kuvame kakhulu ukuhlolwa kwegazi.
- Ukuhlolwa kokuhlola: Ukuhlolwa kwegazi okulinganisa amazinga e-C4 angasetshenziswa njengendlela yokuhlolwa kwegazi ye-angioedema yefa. Amazinga aphansi e-C4 asikisela ukugula okuzenzakalelayo, futhi izinga eliphansi lizobonisa ukuthi udinga ukuhlolwa kwesinye kwegazi ngokuqondile ukuze uhlole ukulahlekelwa kwe-C1 inhibitor. Uma kukhona amathuba okuba unayo i-angioedema yefa, kuzodingeka ulandelelwe ukuhlolwa kwegazi kwe-C1 inhibitor ukuntula. Kodwa uma unethuba eliphansi lokuba ne-angioedema yefa, i-C4 evamile iphakamisa kakhulu ukuthi awunayo isimo.
- Ukuhlolwa kwegazi: Ukuhlolwa kwegazi kubonisa iphutha kumaprotheni e-C1 esterase inhibitor (C1-INH). Izinga le-C1-INH lingase libe ngaphansi kunejwayelekile, noma lingase lijwayelekile kepha lingasebenzi. I-C1-INH iyiprotheni esebenza ukugcina isimiso sakho somzimba sokuvikela omzimba sihlolwe ukuze singagxili. Iphutha lezakhi zofuzo oludala i-angioedema, eliholela emazingeni angavamile eC1-INH noma uthayiphe i-angioedema, eyenza umsebenzi we-C1-INH ongajwayelekile.
- I-Genetic Test: Izinguquko ezithile zezakhi zofuzo ezibangelwa i-angioedema zingatholakala kwisakhi se-SERPING1 sohlobo l no-ll angioedema. Izinguquko ezakhiweni ze-F12 zingabonakala ngohlobo lll angioedema. Umphumela wangempela walokhu okungajwayelekile akuqondakali kahle.
I-angereded i-Hereditary izuzwe njengefa ngokuqondile kubazali abanesimo se-autosomal esiphezulu, okusho ukuthi uma umuntu enegesi yalesi simo, izimpawu zesifo zizokhula. Ngenxa yokuthi i-autosomal ephezulu, noma yikuphi umzali ozuze ifa lohlobo lwe-angioedema l, ll noma lll kufanele libe nezimpawu zalesi simo ngoba kuyisici esibaluleke kakhulu. I-angerede ye-Hereditary ayiyona into evamile, ithinta kuphela abantu abangu-1 kubantu abangu-50,000.
Esikhathini esiningi, i-angioedema ebangelwa lezi zakhi zofuzo izuzwe njengefa kodwa umuntu angakwazi ukuthuthukisa ukuguquka kwezakhi zofuzo, okusho ukuthi kungenzeka ukuthuthukisa izinguquko zofuzo ezibangelwa isimo ngaphandle kokuzuzwa kubazali bakho.
Ukucabanga
Ukucabangela akuvamile ukusiza ekutholeni i-angioedema. Kwezinye izimo, ikakhulukazi uma kunokuphefumula noma lapho izinkinga zomzimba ezinjengezinhlungu zesisu, isicanucanu, kanye nesifo sohudo ziyinkimbinkimbi, ukuhlolwa kwe-imaging yokuhlola ukulawula ezinye izifo kungadingeka.
Ukuhlonza okuhlukile
Kunezinye izimo ezimbalwa ezingase ziveze izimpawu ezifana nezama-angioedema.
Xhumana noDermatitis
Isimo esifana kakhulu ne-angioedema, uxhumano lwe-dermatitis luphumela ekuthintaneni nomuntu okhiqiza i-hypersensitivity. Izimo zifana futhi kungase kube nzima ukutshela umehluko. Ukuxhumana kwe-dermatitis akuhlobene nokuvuvukala, futhi kubangelwa isikhumba esibucayi kakhulu, ubomvu, nokukhwabanisa noma ukuchithwa kwesikhumba.
I-Edema ngenxa yokutheleleka noma ukulimala
I-Edema ukuvuvukala kwanoma iyiphi ingxenye yomzimba. Kungaba khona ekuphenduleni ukulimala noma ukutheleleka, lapho kwenzeka khona ngokushesha futhi ngokungazelelwe, okufana ne-edema ye-angioedema.
Njenge-angioedema, i-edema ngenxa yokulimala noma ukutheleleka kungase kuhileleke kuphela isifunda esikude somzimba. Kukhona umehluko ongaqondakali phakathi kwe-edema, noma kunjalo, kufaka phakathi umkhuhlane kanye nobuhlungu obunzima uma imbangela ingozi noma ukutheleleka.
Ukungaphumeleli Inhliziyo noma Ukuhluleka Kwezinso
I-edema yokuhluleka kwenhliziyo noma ukwehluleka kwezinso ngokuvamile kuhamba kancane kancane. Esikhathini esiningi, i-edema akuyona uphawu lokuqala yalezi zimo.
Ukuhlukana okumbalwa okubalulekile ukuthi i-edema yokuhluleka kwenhliziyo noma ukwehluleka kwezinso kuvamise ukulinganisa, okungadingeki kube yinkinga ye-Angioedema. I-edema ye-angioedema ayifuni, ngenkathi i-edema yokuhluleka kwenhliziyo noma ukwehluleka kwezinso kubeka i-edema.
I-Vein Deep Thrombosis (DVT)
I- DVT ibangela ukuvuvukala kwengxenye eyodwa yomzimba, ngokuvamile umlenze ophansi. Njenge-angioedema, kungase kube ngokuzumayo, okungenabuhlungu, futhi okulinganayo. I-DVT ingabangela ukumbumbana kwamapulmoni, okuholela ekuphuthumeni okuphefumulayo. I-DVT ayilindelekile ukuba ihambisane nokuvuvukala kwezindebe noma amehlo.
Lymphedema
Ukuvinjelwa kokugeleza komthamo kulo lonke umzimba kungenzeka ngenxa yesimiso se-lymphatic system. Lokhu kungenzeka emva kwezinhlobo ezithile zokuhlinzwa, ikakhulukazi ukuhlinzwa komdlavuza.
Eminye imithi ingakhipha i- lymphedema . Ngokuvamile kubonakala ngokuvuvukala engalweni eyodwa futhi kungavamile ukuba khona ngaphandle komlando wezokwelapha okubonisa ukuthi i-lymphatic cause cause.
> Imithombo:
> Bova M, De Feo G, Parente R, et al. I-Angioedema ene-Hereditary ne-Acquired: I-Heterogeneity ye-Pathogenesis ne-Phenotypes ye-Clinical. Int Arch Ukuzivocavoca Immunol. 2018; 175 (3): 126-135. i-doi: 10.1159 / 000486312. Epub 2018 Jan 26.
> I-Pritchard N, i-Horný M, i-Xiao CC, i-Brook CD, i-Platt M, i-Inhalant ye-allergen sensitization iyingozi yokuzimela kwe-angioedema. Am J Otolaryngol. 2018 Mar - Apr; 39 (2): 111-115. doi: 10.1016 / j.amjoto.2017.12.013. Epub 2017 Dec 27.