Indawo entsha yokucwaninga kwe- IBS ibilokhu igxile ekusetshenzisweni kwama-antibiotic njengendlela yokwelapha okungenzeka. Akuwona wonke ama-antibiotic okucatshangwa ukuthi awusizo ku-IBS, kuphela kulawo angenakunywa yisisu ngakho-ke angaba nomthelela kuma- bacteria ngaphakathi kwamathumbu amancane namakhulu . Uma kunqunywe ukuthi ukwelashwa kwe-IBS, ama-antibiotic asetshenziswa kuphela ngesikhathi esifushane.
Kungani ama-Antibiotics asetshenziselwa i-IBS?
Ukusetshenziswa kwe-antibiotics ye-IBS kwenzeka lapho abacwaningi babheka ukufana phakathi kwe-IBS kanye nokukhuphuka kwamabhaktheriya amancane emathumbu (SIBO). I-SIBO yisimo lapho amabhaktheriya angaphezu kwamathambo atholakele ngaphakathi emathunjini amancane. Ukusebenzisa ukuhlolwa kokuphefumula kwe-hydrogen , abacwaningi bathole ukuthi i-sub-set of iziguli ze-IBS ibonakala ihlushwa yi-SIBO. Ama-antibiotiki angenakuqhathaniswa abese ahlolwe imiphumela yabo kumpawu ze-IBS .
Yimiphi Imihlobo Eyasetshenziswa?
Ama-antibiotic alandelayo ahlolwe ngokusebenza kwawo ekuphatheni i-IBS:
- I-Rifaximin (i-Xifaxan)
- Neomycin
- I-Clarithromycin (i-Biaxin)
- I-Metronidazole (Flagyl)
Ingabe Iphumelela?
Ema-antibiotic angenhla, i-Xifaxin yiyona kuphela imithi eye yaboniswa ukuthi iphakeme kune-placebo ekunciphiseni izimpawu kwisigatshana seziguli ze-IBS. I-Xifaxan ibonakala iyasebenza kakhulu ekuqedeni izimpawu zokuvimbela nokuhuda .
I-Xifaxan ivame ukubekezelelana kahle futhi akukho nemiphumela emibi kakhulu eveziwe.
Okubalulekile
Kusukela manje, i-Xifaxan kuphela evunyelwe yi-FDA njengokwelashwa okungezona ukuqotshwa IBS . Kubalulekile ukwazi ukuthi iningi lezifundo kuze kube manje ekusebenziseni ama-antibiotics we-IBS kube yinto emfushane yesikhashana.
Ucwaningo olwengeziwe luzodingeka luqhutshwe ukuze luhlole ukuphepha kwesikhathi eside nokusebenza kwala mithi, kanye nokuhlonza kangcono lezo ziguli ezizozuza kakhulu kuloluhlobo lwezokwelapha.
Imithombo:
I-Ford, A., etal. "I- American College of Gastroenterology Monograph ekuphathweni kwe-Irritable Bowel Syndrome ne-Chronic Idiopathic Constipation " I- American Journal of Gastroenterology 2014 109: S2-S26.
UGaman, A., Bucur, M. & Kuo, B. Ukuthuthukiswa kwezinsizakalo ezenzweni zesisu zomzimba: isifo sofuba esiswini. Intuthuko yokwelashwa ku-Gastroenterology 2009 2: 169-181.
Sainsbury, A. & Ford, A. "Ukwelashwa kwe-Irritable Bowel Syndrome: Beyond Fiber ne-Antispasmodic Agents." Intuthuko yokwelapha ku-Gastroenterology 2011 4: 115-127.