Ezinye iziKhosi zingahle zizenzele ngokuzenzakalela, zi-Dymyelinating
Ingabe i- fibromyalgia ifana ne- multiple sclerosis (MS) kunokuba sicabange? Uhlu oluyingqayizivele locwaningo lwenza lubukeke ngaleyo ndlela, okungenani kwezinye izimo.
Ukuqonda ucwaningo nokuthi kusho ukuthini, okokuqala kufanele uqonde kancane mayelana ne-MS.
Ama-Multiple Sclerosis Basics
I-MS ikholelwa ukuthi iyisifo esizimele , okusho ukuthi isimiso somzimba samasosha omzimba siya e-haywire futhi sihlasela ingxenye yakho, ukholelwa ukuthi i-pathogen futhi idinga ukubhujiswa.
E-MS, inkolelo enkulu kakhulu ukuthi izimpawu zibangelwa into ebizwa ngokuthi i-demyelination , okusho ukuthi isimiso somzimba sokuzivikela sisaphaza okuthiwa i-myelin.
I-Myelin iyi-cell ekhethekile edala umgogodla wezinye izinzwa futhi kuyadingeka ukuthi lezo zinzwa zisebenze kahle. Kufana nokwehliswa kwezingcingo zikagesi. Izindawo lapho i-myelin sheath ibhujiswa khona kuthiwa izilonda.
I-Fibromyalgia & Ukuxoshwa
Ucwaningo lokuqala lwe-fibromyalgia nokudilizwa phansi kwavela encwadini ethi Rheumatology ngo-2008, futhi ukulandelwa kwanyatheliswa ngo-2014 ku- Arthritis & Rheumatology .
Ucwaningo lwango-2008 luphakamisa ukuthi i-subset ye-fibromyalgia ihilela ukuxoshwa komzimba okuzenzakalelayo kanye ne-polyneuropathy (ubuhlungu obuvela emithanjeni ewonakele). Iqhathanisa i-fibromyalgia nesifo sezinzwa okuthiwa i-polyneuropathy engavamile yokuvuvukala, evame ukuphathwa nge-immunoglobulin (IVIg).
Eqinisweni, kulolu cwaningo, basebenzisa i- IVIg ukuphatha abantu kuleli qembu le-fibromyalgia. Kuyavunywa ukuthi kwakuyinkimbinkimbi encane futhi abantu abangu-15 kuphela baphathwa, kepha abacwaningi bathi labo bantu babe nobuhlungu obukhulu kakhulu nobubele kanye nokuthuthukiswa kwamandla, kanye nokuthuthukiswa okuncane kokukhathala nokuqina.
Lesi yisibonelo esihle sokuthi isifundo sokuqala singaba nomthelela omkhulu kangakanani kodwa nokho sinomthelela omncane noma awukho. Yebo, abanye odokotela baye basebenzisa i-IVIg ngeziguli, kodwa akude kakhulu nokwelapha okusabalalisa nokudonswa komzimba ku-fibromyalgia cishe akukhulunywa ngaso.
Ukusheshisa iminyaka eyisithupha, futhi ekugcineni sinezifundo ezilandelwayo ezibonakala ziqinisekisa ukutholakala kwangaphambili kanye nokuthuthukiswa kwazo. Iphinde isekelwe omunye umsebenzi okwenziwe eminyakeni embalwa edlule.
Okuthola Okusha
Okokuqala, abacwaningi babefuna ukuhlola ukuthi ukuchithwa kwezintambo ezinkulu (izinzwa ezinkulu), ezitholakala ekufundweni kwangaphambili, kubangelwa ukuzimela. Khona-ke, babefuna ukuhlola i- fiber encane ye-neuropathy , okunye okuye kwaphakanyiswa ukuthi kuhilelekile ku-fibromyalgia.
I-fibre encane ye-fiber isimonakalo esibuhlungu ezakhiweni zesikhumba, izitho, nezinzwa ezikuvumela ukuba uzizwe unesizathu sokulawula imisebenzi ezenzakalelayo njengezinga lenhliziyo nokushisa komzimba. Abacwaningi banesithakazelo kulolu hlu lokubuza imibuzo ngoba ngezinye izikhathi i-fibre neuropathy encane ihlotshaniswa nezilonda zokudonswa komzimba emagqumeni amakhulu.
Baye bathola izinkomba ze-fiber ezincane ze-neuropathy, kufaka phakathi nomuzwa wokunciphisa emilenzeni engezansi.
Futhi kuhlolwe kwakukhona amamaki amaningi wokusebenza kwe-immune nokusebenza okuzenzakalelayo.
Bathi bathola izinkomba eziphezulu ze-fibre neuropathy encane, ngakho-ke izilonda ezinkulu ze-fibre, emilenzeni yabantu abane-fibromyalgia. Baphinde bathole ukuthi lezi zinkomba, ikakhulukazi ithole, zibonakala zixhunyaniswe nomaka wokusebenza komzimba okubizwa nge-interleukine-2R.
Baphetha ngokuthi inhlanhla encane ye-fibre neuropathy ingase ibe negalelo ebuhlungu bethu, nokuthi ezinye zezinhlungu zethu zivela emisebenzini ye-immune-system, engabandakanya ukuzimela.
Ukubeka Kokuqukethwe
Lolu cwaningo olulandelayo lufika ngesikhathi lapho umphakathi wesithakazelo we-fibromyalgia ubonakala ushintshela ekubhekaneni ne-fiber encane ye-neuropathy, ukuvuvukala, kanye nokwenzeka komuntu ngamunye.
Kuthathwa ngomongo, lo msebenzi wanezela esithombeni esiphuthumayo ukuthi sinezinzwa ezonakele emva kwakho konke, ukuthi izinhlelo zethu zokuphazamiseka zomzimba zihileleke nakanjani, nokuthi ukuzimela noma esinye isici sokuzivikela sisasebenza.
Lokhu kwakusencane isifundo esifushane, kodwa iqiniso lokuthi liye lasiza umsebenzi wangaphambili futhi libonakala likwazi ukugcoba nezinye izinto ezitholakala kamuva kungasho ukuthi kuzoba nomthelela omkhulu kunezigaba zayo. Okungenani, kubonakala sengathi lokhu kuyindlela efanele yokutadisha okufanele iqhubeke.
Ucwaningo olwenziwe kuyi- Medical Science Monitor , olwanyatheliswa ngo-2014, lwathola ukuthi abantu abane-MS banamanani aphakeme kakhulu e-fibromyalgia kunabantu abaningi. Lokhu kungenza kube lula ukuphikisana kwezimo ezisekelwe emsebenzini.
Izwi kusuka
Ukufunda ukuthi isimo sabo sifana ne-MS singaba nezinzuzo zangempela kubantu abane-fibromyalgia. Okokuqala, abantu abaningi bayazi ukuthi yi-MS futhi bayayihlonipha njengesimo esibi. Lokhu kungaholela ekwamukeleni okungcono komphakathi kanye nokwamukelwa kwezwe jikelele emphakathini wezokwelapha. Lokho, kungaholela ekucwaningeni okwengeziwe.
Okwesibili, kunganikeza indlela entsha yokwelapha i-fibromyalgia phakathi kwemithi eyenzelwe i-MS.
Ukufana kufana nengqondo, ngoba zombili izimo zingabandakanya ama-flares nama-remission futhi izimpawu zifana kakhulu. Kungenzeka ukuthi sizoqhubeka nokufunda kabanzi ngalesi sihloko nokuthi izinto ezijabulisayo zingase zifike kuwo.
> Imithombo:
> Caro XJ, Winter EF. Ubufakazi be-fidalal nerve fiber mass ejwayelekile kwi-fibromyalgia: izinkinga zemitholampilo kanye ne-immunological. I-arthritis ne-rhuematology. 2014 Jul; 66 (7): 1945-54. i-doi: 10.1002 / ubuciko.38662.
> Caro XJ, Winter EF, uDumas AJ. I-subset yeziguli ze-fibromyalgia ziye zathola ukusikisela kwesifo sokuphefumula esingapheliyo sokudonswa kwe-polyneuropathy futhi sibonakale siphendula ku-IVIg. I-rheumatology. 2008 Feb; 47 (2): 208-11. i-doi: 10.1093 / i-rheumatology / kem345.
> Clemenzi A, Pompa A, Casillo P, et al. Ubuhlungu obungapheliko ebuchosheni abaningi: ingabe kukhona ne-fibromyalgia? Isifundo sokuhlola. Ukuqapha kwesayensi yezokwelapha. 2014 Meyi 9; 20: 758-66. i-doi: 10.12659 / MSM.890009.