Ukunciphisa Ukuvuvukala Ukuthuthukisa Umsebenzi Wokusebenza
Ekugcineni, iningi labantu abanoma yiluphi uhlobo lwe-chronic lung lungathola ukuthi lithatha imithi elwa nokuvuvukala ngesikhathi esithile lapho belashwa. Imithi ephikisana nokuvuvukala yenza ngcono ukuphefumula ngokunciphisa ukuvuvukala kwamavesi emoyeni. Ezinye imithi elwa nokuvuvukala ithathwa isikhathi esifushane ukusiza ukusheshisa ukuphumula uma isiguli sinesifo sokuphefumula noma enye inkinga ebangela ukuhluleka kokuphefumula.
Ezinye imithi elwa nokuvuvukala ithathwa isikhathi eside ukusiza ukuvimbela imibhalo yomoya evuvukalayo futhi ithuthukise umsebenzi wamaphaphu.
Corticosteroids vs. Anabolic Steroids
Ngaphambi kokuba siphumelele, ake sicacise ukudideka kwabantu abaningi abanakho mayelana negama elithi "steroids." I-steroids esetshenziselwa ukwelashwa kwezifo zamaphaphu yi- corticosteroids , okuyizinto ezihluke kakhulu kune-anabolic steroids esizizwa ngezinye izikhathi ngezemidlalo ezihlukumeza .
I-Corticosteroids: Imithi elingisa imiphumela ye-hormone ekhishwe kwi-adrenal gland ebizwa ngokuthi "i-cortisol," enemisebenzi eminingi emzimbeni kubandakanya ukucindezeleka kokulwa nokuncipha ukuvuvukala.
I-anabolic steroids: Izinguqulo ezihambisana namahomoni wesilisa omzimba okwandisa izici zesilisa. Ngezinye izikhathi abagijimi bawasebenzisa ngokungemthetho ukukhulisa ubunzima bamandla kanye namandla. Kunezimo zezokwelapha ezisemthethweni zokuthi i-anabolic steroids ingahle ibekwe yini, kodwa isifo samaphaphu asilona naso.
I-Oral Corticosteroids
I-oral steroids, efana ne- prednisone , i-prednisolone noma i-methylprednisone, ngezinye izikhathi inikezwa kubantu abane- cystic fibrosis (CF) yokwelapha okwesikhashana. Azinconywa ukwelashwa kwesikhathi eside ngenxa yalokho okungenzeka kube nemiphumela emibi kakhulu ebandakanya lokhu okulandelayo:
- Ukunciphisa ukukhula ezinganeni
- Isifo sikashukela
- I-cataract
- I-osteoporosis
- Ukunciphisa ikhono lokulwa nezifo zamapayipi, njengePseudomonas aeruginosin ebulalayo
I-Steroids engenayo
I-steroids engenalutho, njenge-Qvar (beclomethasone), i-Pulmicort (budesonide) ne-Flovent (fluticasone), ihanjiswa ngqo emaphashini futhi ibe nemiphumela emibi embalwa kunayo i-steroids yomlomo. Kodwa-ke, ukuhlola akubonanga nhlobo inzuzo ethile ye-steroids eside yesikhathi eside yokuthola abantu abane-cystic fibrosis; ngakho-ke, i-Cystic Fibrosis Foundation iyeluleka ngokusetshenziswa kwesimiso se-steroids engatholakali kubantu abane-CF ngaphandle uma beba nesifo se-asthma .
Izidakamizwa ezingezona ezama-anti-inflammatory (NSAIDs)
Njengoba igama lisho ukuthi, ama-NSAID ayingxenye yemithi elwa nokuvuvukala engenayo i-steroids. I-NSAID ayinayo ingozi efanayo yemiphumela emibi njengemithi yokwelapha i-steroidal anti-inflammatory. Kodwa-ke, ukusebenzisa ama-NSAID isikhathi eside kungabangela ukungena kwangaphakathi noma izinkinga zezinso.
U-Ibuprofen, okudayiswa phezu kwe-counter futhi ngomuthi wokugoma, i-NSAID eye yaboniswa ukuthi iphuze ukulahlekelwa umsebenzi wephaphu nokusetshenziswa isikhathi eside kubantu abane-cystic fibrosis. Ngenxa yokuthi inzuzo engaba khona ye-ibuprofen inkulu kunengozi yemiphumela emibi kakhulu, i-Cystic Fibrosis Foundation incoma ukusetshenziswa kwesikhathi eside kwe-odokotela-ibuprofen njengendlela yokwelashwa kubantu abane-cystic fibrosis okungenani abaneminyaka engu-6 ubudala futhi abanesifo se-FEV1 60% noma ngaphezulu.
Okubalulekile: Ungathathi ibuprofen ngaphezulu-i-counter for the long-term treatment of cystic fibrosis ngaphandle kokubonisana nodokotela wakho kuqala.
Umthombo:
I-Flume, P., et al. "Imihlahlandlela ye-Cystic Fibrosis Pulmonary Guidelines: Imithi Engapheli Yokulondoloza Impilo Yengculazi." Am. J. Respir.