I-mesothelium iyisisindo samathambo (amakhemikhali) azungeze futhi avikele izitho zesifuba, isikhumba esiswini nesisu.
Isakhiwo
Amaseli aseMesothelial aqala njengama-mesoderm ngesikhathi sokuthuthukiswa (amaphaphu aphuma e-endoderm) futhi ngokusobala adlala ingxenye ebalulekile ekuthuthukiseni amaphaphu.
I-mesothelium ihlukaniswe ngezifunda ezintathu eziyinhloko:
- I- pleura yilezi zingxube ezimbili ezakha amapulangwe emaphashini. Lokhu, futhi, ihlukaniswe nge-plecer visceral elele ngqo emaphashini, kanye ne-parietal pleura, okuyizingxenye zangaphandle zamaphaphu.
- I-pericardium ibhekisela ku-mesothelium eyenza uhlaka oluzungeze inhliziyo kanye ne- mediastinum , indawo esifubeni phakathi kwamaphaphu.
- I-peritoneum ihlanganisa izingxube ze-mesothelium ezifaka isikhumba esiswini. Lesi sifundazwe sihlukaniswe sibe izingqimba ezimbili. I-perceroneum ye-visceral igxila izitho zangaphakathi, ne-parietal peritoneum, ebeka izindonga zamathumbu nesisu.
Umsebenzi
Kwake kucatshangwa ukuthi injongo eyodwa kuphela ye-mesothelium kwakuwukuhlinzekela indawo elula, engenamathela ukuze ivikele izitho zesifuba nesisu esiswini ngesikhathi sokunyakaza nokuphefumula.
Manje sifunda, okufana namathoni kanye nesithasiselo, i-mesothelium ineminye imisebenzi ebalulekile futhi, futhi isebenza njengekhanda eliguquguqukayo kunokumane nje libe umngcele ovumela ukunyakaza okushelelayo.
Lokhu kufaka:
- Ukuthuthwa nokuhamba kwamanzi okushisa kanye nodaba kulo lonke i-membrane ezivela ezingxenyeni zangaphandle zesifuba nesisu esiswini ezingxenyeni zangaphakathi. Ekulawuleni le misebenzi, izicubu ze-mesothelial zingadlala indima ebalulekile kwi-homeostasis (ibhalansi) yomzimba.
- I-coagulation (i-clotting yegazi)
- Ukuphulukisa
- Umsebenzi we-immune - I-mesothelium ibonakala inendima yokuzivikela ngokumelene nokutheleleka kanye nokusabalalisa izidumbu. Amaseli we-mesothelial e-Pleural akha izinto ezisebenza ngokumelene nama-bacteria, kuhlanganise nalabo abathintekayo ngesifo sofuba.
- Ukuvikeleka ngokumelene nezicubu - Amangqamuzana aseMesothelial avela ezintweni eziphathekayo ezivimbela ukukhula kwezicubu zokugaya ukudla. Lezi zinto zibonakala zivimbela ikhono lomdlavuza wamangqamuzana ukuba "anamathele" kumama-mesothelium, futhi ngaleyo ndlela, ukunciphisa ukusakaza noma imetastasis yezifo ezithile.
Imibandela Yezokwelapha
I-Mesothelioma uhlobo lomdlavuza oluqala emasethlium (kunoma yisiphi isifunda lapho i-mesothelium ikhona khona) Lo mdlavuza uvame kakhulu kubantu abaye bavezwa yi-asbestos ( bheka izingozi ze-asbestos ,) futhi uyaqhubeka nokwanda kwezigameko emhlabeni jikelele.
Izimpawu ze-mesothelioma zingabandakanya ukukhwehlela, ubunzima bokugwinya, ubuhlungu besisu nokubhubhisa, nezinye izimpawu kuye ngokuthi indawo ye-tumor. Inqubo yokuhlinzwa ebizwa nge- pleurodesis (ukususwa kwe-pleura) ngezinye izikhathi isenziwa ukuze isuse lesi sifo, nakuba ukubikezelwa kwesibindi kuvame ukungalungi ngenkathi lo mdlavuza utholakala.
Ukuxhaswa kuyinkinga evamile yokuhlinzwa kwesisu.
Izicubu ezincane ezibandakanya i-mesothelioma emgodini wesisu zingase zenze ama-band of tishu, okuzokwazi ukubopha isilwane futhi zidale ukuvinjelwa. Izimpawu zokubambelela zivame ukuzwa ubuhlungu besisu, ukuphazamiseka nokubhubhisa. Uma ukunamathela kunobumnene (kungabangeli ukuvimbela okuphelele) abantu bangase bahlushwa iziqephu ezingapheli zezihlungu zesisu, ikakhulukazi ngemva kokudla ukudla okukhulu.
I-Fibrosis - Abacwaningi okwamanje baphenyisisa indima okungenzeka ukuthi i-mesothelium enxusayo ingadlala ku-fibrosis, ikakhulukazi izimo ezifana ne- idiopathic pulmonary fibrosis .
Ukusebenza kwamapulangwe noma ukwakheka kwamanzi emzimbeni phakathi kwezingxenye ezimbili ze-pleura (i-mesothelium enesisindo) kuthonywa izinto ezifihliwe ngamangqamuzana omzimba we-mesothelial.
Imithombo:
Batra, H., no-V. Antony. Ama-cell Messelial Pleural in Pleural and Lung Diseases. I-Journal ye-Thoracic Disease . 2015. 7 (6): 964-80.
Kasper, uDennis L .., u-Anthony S. Fauci, noStephen L .. Hauser. Izimiso zikaHarrison zeMithi yangaphakathi. ENew York: imfundo kaMc Graw Hill, 2015. Print.
Kumar, Vinay, Abul K. Abbas, noJon C. Aster. I-Robbins ne-Cotran Pathologic Basic of Disease. I-Philadelphia: Elsevier-Saunders, 2015. Phrinta.
IMikula-Pietrasik, J., Uruski, P., Kucinska, M., Tykarski, A., no K. Ksiazek. Umsebenzi Wokuvikelwa Wamaseli E-Mesothelial Ukulwa Nokukhula Kwama-Peritoneal of Tumorous Tumors: Indima Ye-Soluble ICAM-1. I-International Journal ye-Biochemistry ne-Cell Biology . 2017. 86: 26-31.
I-Mutsaers, S., Prele, C., Pengelly, S., no-S. Herrick. Amaseli Mesothelial ne-Peritoneal Homeostasis. Ukuzala nokuhlunga . 2016. 106 (5): 1018-1024.