Ukukhunjulwa Kwemisebe Ngemva kweKhemotherapy ne-Radiation Therapy
Kuyini ukukhumbula imisebe futhi yini okufanele uyazi uma uthola (noma uthola) kokubili i-chemotherapy kanye nokwelashwa kwemisebe yomdlavuza wamaphaphu?
Sibutsetelo
Ukukhunjulwa kwemisebe kuyindlela yokuvuvukala eyenzeka ngezinye izikhathi lapho umuntu ethola i- chemotherapy elandela ukwelashwa kwemisebe yomdlavuza. Izimpawu zingenzeka ezinsukwini ezimbalwa emva kokuba ukwelapha imishanguzo igcwaliswe, noma ngemva kweminyaka.
Akuqiniseki ukuthi lokhu kwenzeka kaningi kangakanani, kepha ucwaningo olulodwa lucatshangelwa ukuthi lwenzeka ngamaphesenti angu-9 abantu abahamba ngokubili ukwelashwa kwama-radiation kanye ne-chemotherapy yomdlavuza.
Izimpawu
Izimpawu zokukhumbula i-radiation zibangelwa ukuvuvukala esifundeni esaphathwa ngaphambilini ngemisebe.
Imisebe ikhumbula i-dermatitis - Uhlobo oluvame kakhulu lokuphendula yi-radiation recall dermatitis, ukuqhuma kwesikhumba okubandakanya ukubomvu, ukuvuvukala, kanye / noma ukuphuza isikhumba. Ukuvuthwa kuvame ukuba buhlungu futhi kungabonakala ukushisa kwelanga okukhulu. Lokhu kuvame ukulandelwa ukukhishwa okulandelwa ukulandelwa kwesikhumba ngemuva kokuphulukiswa. Ubude besikhathi ukuqhuma kuthatha kungahluka emahoreni ambalwa nje kuya ezinsukwini ezimbalwa.
Imisebe ikhumbula i-pneumonitis (ukuvuvukala kwamaphaphu) - Ukukhumbula imilayezo kungathinta amaphaphu. Njengoba ukushisa kwe-pneumonitis okungahambisani nokukhumbula kungase kwenzeke kwabanye abantu ngemuva kokwelapha imishanguzo, lokhu kungase kube nzima ekuqaleni ukuhlukanisa.
Ngokujabulisayo baphathwa ngezindlela ezifanayo.
Ezinye izifunda ezingase zithinteke zifaka umlomo (i-radiation recall mucositis), i-larynx, isisu, isisu, isisu esincane, imisipha (i-radiation recall myositis), nobuchopho.
Izimbangela
Akekho owazi kahle ukuthi yini ebangelwa ukusabela kwemisebe yokukhumbula, kanti imibono eminingi iye yahlongozwa.
Inkolelo evamile ukuthi uhlobo oluthile lwe-hypersensitive response reacted by the combination of radiation and chemotherapy.
Imithi Engaba Yimbangela
Nakuba ukukhumbula imisebe kuye kwabikwa kakhulu ngemithi yokwelapha i-chemotherapy, eminye imithi, njengama-antibiotics ngisho nama-herbal supplement, iye yaxhunyaniswa nokuphendula okukhipha imisebe.
Imithi eminingi yamakhemikhali ebizwa ngokuthi yi-chemotherapy ivunyiwe eminyakeni yamuva futhi kubalulekile ukucabangela ukukhumbula i-radiation uma othile eveza noma yiziphi izimpawu ezintsha zokuvuvukala ngenkathi ekhishwa ngamakhemikhali. Imithi ye- chemotherapy ngokuvamile ehlotshaniswa nokukhumbula imisebe ihlanganisa:
- I-Adriamycin (doxorubicin)
- I-Doxil (i-liposomal doxorubicin)
- I-taxotere (i-docetaxel)
- I-Taxol (paclitaxel)
- I-Gemzar (gemcitabine)
- I-5-FU (i-fluorouracil)
- I-Xeloda (capecitabine)
- I-Cosmegen (i-dactinomycin)
- I-rheumatrex (methotrexate)
Ngomdlavuza wamaphaphu, ukukhumbula ukushiswa kwemisebe kwabikwa futhi esigulini kulashwa okuhlosiwe iTarceva (erlotinib) emisebeni elandelayo.
Ukuxilongwa
Akukho ukuhlolwa okucacile okuchaza ukukhumbula imisebe, nakuba ukuqhuma kwesikhumba kungahle kuvelele. Njengoba kuphawuliwe ekuqaleni, noma nini lapho umuntu eqala ukuvuvukala emthonjeni omusha ngemuva kokuphulukiswa ngaphambili nge-radiation therapy lapho, kungenzeka ukuthi kucatshangelwe ukuthi ukukhumbula imisebe.
Ngokuphawulekayo ukuthi indawo ehilelekile yayijwayelekile kakhulu ngaphambi kokuvuvukala kwamanje. Ngamanye amazwi, akuyona ukuwohloka kokushona okwenziwe yimisebe ngesikhathi sokwelapha.
Ukwelapha
Ukwelashwa kwemiphumela yokukhumbula imisebe ngokuyinhloko kukunakekelwa kokunakekela-izimpawu zokuphatha kuze kube yilapho inkinga ixazulula yedwa.
Ukuqeda umthombo wokuphendula (isibonelo, ukuyeka imithi yokwelapha i-chemotherapy njengomuzwa wemfanelo) ngokuvamile kuyisinyathelo sokuqala. Ukukhumbula imilayezo kubonakala sengathi kukhona izidakamizwa ezithile ukuze ukushintshela komunye umuthi kungase kungabangeli izinkinga uma leso yisisombululo.
Imithi efana ne- corticosteroids kanye nama-anti-inflammatory amalungiselelo angasetshenziswa kwezinye izimo ukunciphisa ukuvuvukala.
Ukuze uthole i-dermatitis yokukhumbula i-radiation, ukugqoka izingubo ezingavamile okugqoke izingubo ezingenalo ukucasula kungenza ube ngcono nakakhulu. Ukucindezeleka okupholile kuye kwasiza abanye abantu ukuthi baphathe ukukhathazeka, kodwa kubalulekile ukuhlola nodokotela wakho mayelana nezincomo zakhe. Nakuba ukuqhuma kuphulukisa, kubalulekile futhi ukugwema noma yini engadala ukuqhuma, njengokungathi ukushisa kwelanga nokushisa kwelanga.
Ukuvimbela
Ngeshwa, akunakwenzeka ukubikezela ukuthi ngabe omunye uzosabela yini kumuthi othile we-chemotherapy noma enye imithi ngemuva kokwelapha imishanguzo. Uma umuntu ephendule ukukhumbula ukukhipha imisebe ngesinye isikhathi, futhi akaqiniseki ukuthi kuzokwenzeka okwesibili.
Ukukhumbula imilayezo kubonakala kungavamile uma isikhala phakathi kwe-radiation therapy kanye ne-chemotherapy sikhulu, kepha ukukhulisa isikhathi phakathi kwe-radiation therapy kanye ne-chemotherapy kungase kungabi yisinqumo esingcono uma umdlavuza ucatshangwa ukuthi uphendule kangcono ukuthi lezi zindlela zisondelane.
Imithombo:
Awad, R., noL. Nott. I-radiation ikhumbula i-pneumonitis eyenziwe i-erlotinib ngemuva kwe-radiotherapy ye-thoraic thoraic yomdlavuza wamaphaphu: Umbiko we-Case kanye nokubuyekezwa kwezincwadi. I-Asia Pacific Journal ye-Clinical Oncology . 2016. 12 (1): 91-5.
I-Azria, D. et al. Ukukhunjulwa ukukhumbula: into ehlonziwe kahle kodwa enganaki. Ukubuyekezwa kweCanscer Treatment . 2005. 31 (7): 555-70.
UBurris, H. noJ. Ukushona kwemikhumbuzo ukukhumbula nge-antiticancer agents. I-Oncologist . 2010. 15 (11): 1227-37.
I-Caloglu, M. et al. Isimo esiyinkimbinkimbi semisebe nemithi: khumbula ukuphendula. Onkologie . 2007. 30 (4): 209-14.
Kodym, E. et al. Ukuphindaphinda kwama-radiation ukukhumbula i-dermatitis kumagciwane omdlavuza omdala. Onkologie . 2005. 28 (1): 18-21.