Ukusetshenziswa Okufanele Kuchazwe Ngokukhulu Ngemihla Eceleni
I-Tylenol (i-acetaminophen) wuhlobo lwemithi yokwelapha enezici ezimbili ze- analgesic ne-antipyretic. I-analgesic isetshenziselwa ukuhlinzeka ngosizo lwezinhlungu, kuyilapho i-antipyretic isisiza ukunciphisa umkhuhlane.
Kukhona abantu abaningi abakholelwa ukuthi iTylenol inhle kakhulu into efana ne- aspirin , i- Advil (ibuprofen) , noma i- Aleve (naproxen) , kodwa kukhona umehluko owodwa oyisihluthulelo: lezi zintathu zokugcina ziyingxenye yezidakamizwa ezaziwa njenge- nonsteroidal anti-inflammatory izidakamizwa (ama-NSAID) .
Ngenkathi i-NSAID nayo ine-analgesic kanye ne-antipyretic, inganciphisa ukuvuvukala okubangelwa izimo ezifana ne-arthritis, bursitis, ne-tendinitis. I-Tylenol ayikwazi.
Naphezu kwalokhu nokuhlomula okungeziwe, ama-NSAID anemiphumela emibi kakhulu engaba yingozi ekunciphiseni ukusetshenziswa kwabo. Ngakho-ke, futhi iTylenol noma i-NSAID ingabhekwa ngokuthi "ingcono" kunomunye; bavele basebenzise ngendlela efanele.
Indlela iTylenol ne-NSAID ehluke ngayo
I-Tylenol isetshenziswa ngokuyinhloko ukuphatha izinto ezinjengokukhanda ikhanda, umkhuhlane, ukuphuza imisipha, i-backache, amazinyo, nokubandayo. Ngenkathi uhlelo oluqondile lwezenzo lungasaqondakali, iTylenol ikholelwa ukuthi inqanda i-enzyme ebizwa nge- COX-2 ngendlela eqinile kune-NSAID. Ngokwenza kanjalo, kuvimbela ubuchopho ukuthi bukhulule amakhemikhali asebenze izinkinga zokubuhlungu.
Ngenkathi i-NSAID yenza izinto eziningi ezifanayo, iyakhuthaza ukukhiqizwa kwe- prostaglandin , i-hormone-like compound ekhuthaza ukuvuvukala.
I-Prostaglandin nayo inehluke ekuvikeleni isisu emiphumeleni eyingozi ye-aces digestive.
Futhi, kukhona okunye kwezinselelo ezinkulu zokusetshenziswa kwe-NSAID: njengoba amazinga e-prostaglandin anciphisa kanjalo, futhi, ukuzivikela kuyazuzisa esiswini. Ngenxa yokuthi iTylenol inomthelela omncane ku-prostaglandin, imiphumela yaso emibi yemathunjini ayinzima kakhulu.
Ukuqhathanisa imiphumela emibi
Ukusetshenziswa kweTylenol ne-NSAID ikakhulukazi kuchazwe ngemiphumela yabo emibi.
Imiphumela emibi ye-Tylenol ayincane kakhulu futhi ingafaka ukukhushulwa kwesisu, isicashu, ukulahlekelwa kwesifiso, nokukhanda ikhanda. Ngesinye isikhathi, ukuchithwa nokugqwala kungabuye kuthuthuke.
Ngokuphambene, ama-NSAID angabangela ukugubha, ukuzwa kwesisu, nezilonda zamapulpress . Ukusebenzisa isikhathi eside noma ngokweqile kungathinta ukucindezeleka kwegazi nokugaya futhi kwandise ingozi yokuphuma kwegazi, umfutho wegazi ophakeme, i- edema ye-edema (ukuvuvukala komlenze), ukuhlaselwa yinhliziyo, nokushaya isisu.
Ngokwengxenye yayo, i-Tylenol ayihlotshaniswa nengozi ye-cardiovascular noma peptic ulcer. Kodwa-ke, kungabangela ukulimala okukhulu kwesibindi uma kusetshenziselwa ngokweqile (ngaphezu kuka-4 000 milligrams ngosuku) noma kuthathwe utshwala.
Ngenkathi ama-NSAID angabangela ubuhlungu kwesibindi uma isetshenziswe ngokweqile, ingozi iyinto encane kakhulu. Okufanayo kusebenza ezinso kodwa kuvame kuphela uma kunesifo esiyinkimbinkimbi yengqondo.
Ukuphikisana nama-Painkillers
Njengomthetho, awukwazi ukuphindaphinda kabili kuma-NSAID ngenxa yengozi eyengeziwe yemiphumela emibi yamathunjini kanye nenhliziyo. Ngokufanayo, ngeke ufune ukwenza umkhuba wokuphindaphinda umthamo wakho we-Tylenol kusukela ubuthi obunobindi obungathuthuka ngomthamo wansuku zonke okungenani ama-milligram angu-3 000 (noma ayisithupha ama-caplett Tytenol Extra Strength).
Uma kuthiwa, akukho lutho olungalungile uma unquma ukwengeza ama-NSAID akho nsuku zonke nge-Tylenol. Uma, isibonelo, i-Advil noma i-Aleve yakho ingakunikezi usizo lwe-arthritis oludinga, ungathatha iTylenol kamuva ngosuku uma uhlala ngaphakathi kwesilinganiso esinconywayo.
Ngakolunye uhlangothi, uma unesifo sokukhubazeka kwezinso noma isifo senhliziyo (njenge-hepatitis B noma C), kuzodingeka usebenze nodokotela wakho ukuze usebenzise ukusetshenziswa kwakho noma uthole ezinye izindlela ezingeke zibe nomthelela ekulimaleni komzimba.
Izwi elivela
Ngesikhathi sekuqala izimpawu ze-arthritis , abantu bazovame ukuzisebenzisa imithi futhi basebenzise ubuhlungu njengendlela eyodwa kuphela yokwelashwa okuncane noma okuncane.
Nakuba lokhu ngokuvamile kungabangeli izinkinga ezinyathelweni zokuqala, kungaba yinkinga uma isimo sidlulela futhi ukunakekelwa kahle kwezokwelapha akufunwa.
I-arthritis yisifo esidinga ukuphathwa. Ngokusebenza nodokotela, ungagwema ukubhekana nezinkinga zokwelapha futhi uthole izixazululo eziphathelene nemithi futhi ezingekho emithi ezinganikeza usizo ngaphandle kokulimaza impilo yakho.
> Imithombo:
> Bally, M .; Dendukuri, M .; Rich, B. et al. "Ingozi ye-infarction eyingozi ye-myocardial nama-NSAID ekusetshenzisweni kwezwe langempela: ukuhlaziywa kwe-betaesi ye-Bayesian yedatha yesiguli ngasinye." BMJ . 2017; 357: j1909. I-DOI: 10.1136 / bmj.j1909.
> Scheiman, J. "Ukulimala Kwamazinyo Okubangelwa NSAID: Ukuvuselelwa Okugxilwe Kogokotela." J Clin Gastroenterol. 2016; 50 (1): 5-10. I-DOI: 10.1097 / MCG.0000000000000432.
> Yoon, E .; I-Babar, A .; Choudhary, M. et al. "I-Acetaminophen-Yenza I-Hepatotoxicity: Isibuyekezo Esizwakalayo." J Clin Transliter Hepatol. 2016; 4 (2): 131-42. I-DOI: 10.14218 / JCTH.2015.00052.