Ikakhulukazi Kwabesifazane Abasha Abancane, Ukuhlaselwa Inhliziyo Kungenzeka Kungenxa Yezinhlekelele
Sekuyiminyaka eminingana, izazi ze-cardiologists ziye zazi ukuthi izifo ze-coronary artery (CAD) kwabesifazane zingahluka kakhulu kunamadoda. Izimpawu zabesifazane zingase zihluke , izivivinyo zokuxilonga ezisetshenziselwa i-CAD zinganikeza impendulo "engalungile" kwabesifazane , futhi isifo esiyisisekelo ngokwayo singase sihluke kakhulu .
sekuye kwacaca ukuthi kukhona omunye umehluko endleleni i-CAD "eziphatha ngayo" kwabanye besifazane.
Kwabesifazane abasebasha abane- infarction ye-myocardial (ukushaya kwenhliziyo) , i-coronary thrombosis (i-clot i-blood in a coronary artery) eyenza umonakalo we-cardiac ingabangelwa ukuguguleka kwe- plaque ye- atherosclerotic , kunokuba kube nokuqhekeka okuvamile kwesibalo . Uma ukuhlaselwa kwenhliziyo kubangelwa ukukhukhula kwamanzi, izimpawu zingase zibe ezicashile futhi zingavamile kunokuba zihlaselwe yinhliziyo "evamile". futhi angase aphuthelwe (noma axhunyiwe) udokotela. Ngenxa yalokho, ukwelashwa kungase kubambezeleke futhi imiphumela ingaba yimbi kakhulu.
Indlela Inhliziyo Ehlasela Ngayo Ngokuvamile
Ngokujwayelekile, i-coronary syndrome eyingozi (i-ACS) ibangelwa ukuqubuka kwesikhala. Ukuqhekeka kwe-plaque ngokuvamile kuyisenzakalo esibucayi nesicacile esibangela imiphumela ngokushesha. Ukuphuka kuveza "i-gunk" ngaphakathi kwe-plaque (i-cholesterol, i-calcium, amaseli avuthayo, nezinye izinto) ukuya egazini - futhi lokhu kuvame ukudala ukwakheka okusheshayo kwe-clot.
Ngokuvamile, i-clot ibangela ukuvinjelwa okuphelele (noma okucishe kuqedile) kwe-artery coronary, futhi ukugeleza kwegazi kuya engxenyeni ye-muscle yenhliziyo ehlinzekwa yilo mshini uvaliwe. Lokhu kuvimbela kuvame ukuholela ezimweni eziphuthumayo futhi eziphawulekayo ezihambisana ne-ACS - izimpawu zesifo senhliziyo noma i- angina engazinzile , noma ngisho nokufa okungazelelwe komzimba .
Yini Eyenza I-Aron Coronary Erosion ihluke?
Kubonakala sengathi, ikakhulukazi kwabesifazane abanesifo senhliziyo ngaphambi kweminyaka yobudala engama-50 (ikakhulukazi, kubesifazane besifazane abangaphambi komama), ukubhuka kwamapayipi ngokuvamile akuyona imbangela ye-clot yegazi. Esikhundleni salokho, i-clot ingase ibangelwe ukuguguleka kwesidonga segazi.
Uyini umehluko phakathi kokuphuka nokukhukhula? Yebo, ukuphuka kwe-plaque kufana ne-pimple evulekile. (Eqinisweni, izinto ezingaphakathi ngaphakathi kwezinto ezijwayelekile azifani neze nezinto ngaphakathi kwe-plaque ye-atherosclerotic.) Kodwa ukuguguleka komzimba kufana nesilonda esingenalutho. I-plaque ehlobene nokuguguleka kungenzeka ibe encane kakhulu, noma kungase kube khona i-plaque ngaphansi kokuguguleka nhlobo.
Ukuguguleka, njengokuqhekeka kwe-plaque, kungabangela ukwakheka kwegazi legazi. Kodwa-ke, ngoba ukuguguleka (ngokungafani nokuphuka), akusona umcimbi omubi, i-clot ngokuvamile idala kancane kancane. Ngakho-ke, izimpawu zingase zithuthuke kancane kancane, zibe nobuqili obuningi, futhi ngokuvamile ziba "ezingokoqobo."
Kungani Lokhu Kubalulekile?
Kuye kwaziwa iminyaka eminingi ukuthi, ngenkathi ukuhlaselwa yinhliziyo kwabesifazane abasebasha kuyinto engavamile, lapho kwenzeka laba besifazane bavame ukuba nemiphumela emibi kunamadoda aneminyaka efanayo. Lezi zimbi ezimbi kakhulu, manje zivela, zingase zibe okungenani ingxenye ngenxa yokuthi eziningi zalezi zifo zenhliziyo zibangelwa ukuguguleka komthambo we-coronary.
Akukhona nje kuphela ukuthi izimpawu ezine-artery coronary ukukhukhula okungenzeka ukuthi zixoshwe njenge-heartburn, ukukhathazeka noma ezinye izimbangela ezingezona zomzimba, kodwa futhi ama-clots ngokwawo angagcina abe yingozi ngaphezu kwamaqabunga akhayo ngenxa yokuphuka. Njengoba kuphawuliwe, ama-clots afana nokukhukhula ajwayele ukuthuthukisa kancane kancane. Ngenxa yalesi sizathu (futhi ngenxa yokuthi izimpawu ezibangelwayo ngokuvamile azivezi kakhulu) lawa macwecwe anesikhathi sokuvuthwa. Ngakho-ke, ngenkathi kutholakala ukuhlaselwa kwesifo senhliziyo, ama-clots ayakhula, aqinile, futhi kunzima kakhulu ukubuyela emuva.
Ukubona i-Coronary Artery Erosions
Ngeshwa, umthambo we-coronary ukuhlukunyezwa kunzima kakhulu ukuyihlolisisa ngaphambi kokuba kubangele i-thrombosis.
Ngokuvamile abakwazi ukubona, ngokwesibonelo, ngesikhathi sokugaya inhliziyo noma ukucindezeleka / ukuhlolwa kwe-thallium . Ngakho-ke umthambo wokuguguquka komzimba ungomunye uhlobo lwe- coronary artery disease ehlotshaniswa nemithambo ye- coronary "evamile" .
Ubani othola i-Coronary Artery Erosions?
Ngesikhathi noma ubani engakwazi ukuhlakulela umthambo we-coronary, lokhu kubonakala sengathi yisimo esiningi kakhulu sokubonakala kubesifazane besandulela, ikakhulukazi ababhemayo be-premenopausal. Ngakho-ke, ngenkathi ukubhema kuyinto engozini kunoma ubani, kuyisimo esiyinhloko esicindezelayo engozini ye-coronary artery erosions. Yisizathu esihle kakhulu sokuthi kungani abesifazane abasha ababhemayo kufanele bayeke.
Kukhona nobufakazi bokuthi ukuguqulwa kwe-coronary emva kokuhlukunyezwa kungahle kubonakale kaningi kulabo besifazane abaye baphazamiseka ngokuphindaphindiwe kwemithambo ye-coronary, efana ne- Prinzmetal's angina .
Isifingqo
I-CAD yabesifazane abasebancane kaningi isifo esihlukile kakhulu kune "i-CAD yakudala" ebonakala emadodeni nakwabesifazane abadala. Ukuqaphela leli qiniso kuholele emizamweni yokuthola ukuqonda okugcwele kwalezo zingxabano nokuthuthukisa amasu aphumelele kakhulu ekwelapheni.
> Imithombo:
> Genuardi L. Burzotta F, Veralio R, et al. Ukushisa kwe-Plaque kubangelwa isigaba se-ST Ukuphakama kwe-Myocardial Infarction: Umbiko we-Optical Coherence Ichungechunge olubhaliwe lwe-Tomography nokubukezwa kwezincwadi ze-Concise. I-Coronary Artery Disease 2017; I-Doi: 10.1097 / MCA.0000000000000463
> Kramer MCA, Rittersma SZH, de Winter RJ, et al. Ukuthintana Kwe-Thrombus Ukuphulukisa Kuya Ngokwemvelo I-Plaque Morphology Ekufeni Kwe-Coronary Okungazelelwe. J Am Coll Cardiol 2009; I-DOI: 10.1016 / j.jacc.2009.09.007.
> Zoccai G, Peruzzi M, Romagnoli E. Ingabe i-Pathophysiology ye-Plaque Injury ku-Acute MI eguqukayo? Ukubukezwa kabusha kwe-Plaque Erosion vs. Ukukhishwa. Kamuva ku-Cardiology. I-American College of Cardiology 2016; http://www.acc.org/latest-in-cardiology/articles/2016/02/26/09/34/is-the-pathophysiology-of-plaque-injury-in-acute-mi-changing (eyatholakala ngoFebhuwari 26, 2017)