Isifo se-Celiac empeleni sisimweni esivamile, kodwa ngeke uqaphele ukuthi kuvame kangakanani ukuthi abantu abaningi abanalo akutholakalanga. Ngenxa yokuthi i- celiac isimo sezakhi zofuzo - ngamanye amazwi, udinga ukuba nezakhi zofuzo "ezilungile" ukuzithuthukisa - izinga lesifo se-celiac lihluka kakhulu ezweni lonke.
E-United States, cishe umuntu ngamunye kubantu abangu-133 unesifo se-celiac , okusho ukuthi cishe abantu abayizigidi ezingu-2.4 banesimo.
Kodwa-ke, ngaphezu kwezigidi ezingu-2 zalezi zingakatholakali, ngakho abazi ukuthi banesimo futhi ngakho-ke kudingeka balandele ukudla okungenalutho kwe-gluten .
Abantu abanezingane ezincane kakhulu zaseCaucasus babonakala benengozi enkulu yokuthuthukisa isimo kunalabo abanamakhosikazi ase-Afrika, aseSpain noma ase-Asia.
Isibonelo, isifundo esisodwa esisekelwe e-US sitholwe ukuthi u-1% wabantu abangewona amaSpanishi babenecala, uma kuqhathaniswa no-0.2% wabantu abamnyama abangabaseSpanishi kanye no-0.3% we-Hispanics.
Olunye ucwaningo lwathola amanani aphezulu kakhulu e-celiac - aphakathi kuka-3% - phakathi kwabantu abanezizukulwane zaseNingizimu Afrika (Punjab), namazinga aphansi kulabo abanezizukulwane zaseMpumalanga Asia, South Indian naseSpanishi. Abantu abanesizukulwane samaJuda nabaseMpumalanga Ephakathi babenezifo ze-celiac ezibangelwa isilinganiso se-US, kodwa labo abanezinzala ezingama-Ashkenazi abangamaJuda babenamazinga aphezulu we-celiac, kuyilapho labo abanesizukulwane se-Sephardic Jewish babenamazinga aphansi.
Ngokumangazayo, leso sifundo sathola amanani afanayo we-celiac kokubili amadoda nabesifazane. Ucwaningo olwedlule lwaluphakamisile ukuthi leliac isivamile kakhulu kubantu besifazane .
Izifo ze-Celiac kubhekwa njengingavamile emazweni lapho abantu abaningi bengabona khona amaSpanishi abamhlophe, nakuba abacwaningi bakholelwa ukuthi izibalo zalo zikhula emhlabeni jikelele.
Yini Engenza Ingozi Yami Iphakeme Noma Iphansi?
Ngamazwi amabili: izakhi zakho zofuzo.
Isifo se-Celiac siye sahlotshaniswa ngokuqinile namagciwane amabili athile: i- HLA-DQ2 (i-primary caliac geni geni) ne- HLA-DQ8 . Uma uthwala ikhophi eyodwa yalezi zakhi zofuzo, ingozi yakho ingaphezulu kweyabantu abaningi. Uma uthwala amakhophi amabili, ingozi yakho iphakeme nakakhulu.
Yiqiniso, ukuthwala isakhi kuphela akusho ukuthi uzokuthuthukisa i-celiac (empeleni, izinkinga zisalokhu ziphikisana nalo).
Izinto okuthiwa "izakhi zofuzo zama-celiac" zihle kakhulu, ikakhulukazi uma unesizukulwane saseCaucasus, futhi kuphela phakathi kuka-1% no-4% kulabo abanamagciwane azoqhubeka nokuthuthukisa leliacac. Kunezinye izici ezisemdlalweni, eziningi zazo abacwaningi bezokwelapha abangazange bazenze okwamanje.
Angizange ngine-Gene Test Test - Iyini Ingozi Yami?
Ngisho noma ungazi ukuthi yiziphi izakhi oziphetheyo, ungase ukwazi ukwahlulela ingozi yakho ngokusekelwe emlandweni wezokwelapha komndeni wakho, ngoba labo abanesihlobo esiseduze abaye bathola ukuthi nabo basengozini enkulu ye-celiac.
Uma unesihlobo sokuqala-umzali, ingane, umfowenu noma udade - womuntu onesifo se-celiac, ucwaningo lubonisa ukuthi une-1 ku-22 amathuba okuthuthukisa lesi sifo esikhathini sakho sokuphila. Uma ungumzali wesibili-degree - ugogo, umalume, umshana, umshana wakho, ugogo nomkhulu, umzukulu noma umntakwabo - ingozi yakho ingu-1 ngo-39.
Kungakhathaliseki ukuthi ubungozi bakho besifo saloliac, ucwaningo lwezokwelapha lubonisa ukuthi kuyinto evamile (nakuba ingaqondakali) isimo sezokwelapha esixhunyiwe. Eqinisweni, ngokusho kweWm. I-K. Warren Research Research Center ye-Celiac Disease Research e-San Diego, isifo se-celiac sifana kabili njengesifo sikaCrohn, isifo se-ulcerative colitis , ne- cystic fibrosis ehlangene.
( Ehlelwe nguJane Anderson )
Imithombo:
I-Choung RS et al. T Trends kanye nokungalingani ngokohlanga / ubuhlanga ezinkingeni ezibhekene ne-gluten e-United States: okutholakala ku-National Health and Nutrition Examination Surveys kusukela ngo-1988 kuya ku-2012. I-American Journal of Gastroenterology. 2015 Mar; 110 (3): 455-61.
Fasano A et al. Ukusabalala kwesifo se-celiac ezingxenyeni ezingozini futhi ezingekho engozini e-United States: isifundo esikhulu semithombo eminingi. I-Archives of Medicine yangaphakathi 2003; 163: 286-92.
Krigel A et al. Ukuhluka Kwezizwe E-Duodenal Villous Atrophy Ngokuvumelana Nezifo Ezibucayi E-United States. I-Gastroenterology Clinic ne-Hepatology . 2016 Meyi 4. pii: S1542-3565 (16) 30145-8.
Izikhungo zezempilo zikazwelonke. Kufinyelelwe: Februwari 2, 2009. http://digestive.niddk.nih.gov/ddiseases/pubs/celiac/index.htm#common
I-Rubio-Tapio A et al. Ukusabalala kwesifo se-celiac e-United States. I-American Journal of Gastroenterology. 2012 Oct; 107 (10): 1538-44.
Isikhungo se-University of Chicago Celiac Disease. Kufinyelelwe: Februwari 2, 2009. http://www.uchospitals.edu/specialties/celiac/
I-University of Maryland Centre for Research Celiac. Kufinyelelwe; Februwari 2, 2009. http://www.celiaccenter.org/celiac/faq.asp#common
I-Wm. K. Warren Medical Research Center for Celiac Disease Research. Kufinyelelwe: Februwari 2, 2009. http://celiaccenter.ucsd.edu/learn_more.shtml