Ukuhlukana Phakathi Kwama-Niacin Supplements
I-Niacin isisongezelo esithandwa kakhulu kulabo abazama ukugcina amazinga abo e-lipid ngaphakathi kwezinga elihle. Ucwaningo lubonise ukuthi i-niacin inganciphisa i-cholesterol ye- LDL ne- triglycerides futhi ingaphakamisa i- cholesterol ye- HDL . Ngenxa yokuthi unamandla okuthinta zonke izici zephrofayili yakho ye-lipid, kungase kube nzima ukuya ekhemisini yangakini noma esitolo sokudla ukuze uthole ibhodlela.
Kodwa-ke, uma ufika engxenyeni ye-niacin ye-supplement esitelekeni, ungase uhlangabezane nezinqwaba ze-niacin supplements. Ngaphambi kokuba ufinyelele leli bhodlela le-niacin, funda indlela yokuhlukanisa phakathi kwezinhlobo ezahlukene ze-niacin ongazithola emashalofini.
Khuluma noMhlinzeki Wezempilo Wakho Okokuqala
Ngaphambi kokuba uthenge futhi uqale ukuthatha isandulisi se-niacin-noma noma yimuphi umnikelo-kufanele ukhulume nomhlinzeki wakho wezempilo. Nakuba i-niacin ibonakala ithuthukisa iphrofayili yakho ye-lipid, ukubuyekezwa kwe-niacin ka-2017 ka-2017 kutholakale ukuthi izinzuzo zokwelashwa kwe-niacin ukuvimbela isifo senhliziyo noma ukunciphisa ukufa kwakungenakwenzeka, ngokulinganisela ukuze kube nobufakazi obuphezulu ngokumelene nalo.
Ucwaningo olulodwa olubanzi (isifundo se-AIM-HIGH) sibonise ukuthi ukuthatha i-niacin enwetshiwe enwetshiwe akuvimbeli isifo senhliziyo noma ngaphezulu kokuthatha isitatimende sodwa. Ukwengeza, abantu abathatha i-niacin kulolu cwaningo babe nesigameko esiphezulu sokubhekana nesifo socwaningo lwe- ischemic .
Ngisho noma iningi lama-niacin supplements lidayiswa phezu kwe-counter, lokhu akusho ukuthi angeke kuthinte kabi impilo yakho. Ngokwesibonelo, i-niacin ingase ihlanganyele neminye imithi oyithathayo. Ukwengeza, i-niacin ingabangela imiphumela emibi noma ifinyelele izimo ezithile zezokwelapha.
Imihlahlandlela yamanje ayincoma ukusetshenziswa kwe-niacin ekwelapheni amazinga e-cholesterol.
Uma umhlinzeki wakho wezezempilo ethi kulungile ukuthi ungeze i-niacin ekwenzeni i-cholesterol-ukwehlisa umgomo, kufanele usazise ukuthi uthatha i-niacin, kanye nanoma yiziphi ezinye izithako kanye nemithi oyithathayo, kubo bonke abahlinzeki bakho bezempilo. Lokhu kuzobasiza ukuba bahlole noma yikuphi ukusebenzisana kwezidakamizwa noma izimo zezokwelapha ezingase zithuthuke.
Akuzona zonke izakhi ze-Niacin Ezidalwa Ezilinganayo
Kunezinhlobo ezintathu eziyinhloko ze-niacin ezitholakala ngaphezu kwe-counter njenge-supplement:
- I-Nicotinic acid
- Nicotinamide
- I-inositol hexanicotinate (i -niacin engenamanzi )
Ucwaningo oluningi oluhlola umphumela we-niacin ekunciphiseni amazinga e-lipid kuhilelekile ukusetshenziswa kwe-nicotinic acid. Nakuba i-nicotinamide ne-inositol i-hexanicotinate yizinhlobo ezithandwayo ze-niacin ngenxa yokuntuleka kwe-flush ehambisana ne-nicotinic acid, kukhona ubufakazi obuncane kakhulu bokuthi lezi zinhlobo ze-niacin zinganciphisa amazinga we-lipid. Ngisho noma amabhodlela amaningi angase abizwe ngokuthi i-niacin, kufanele uhlole ilebula lebhodlela ukuqinisekisa ukuthi yiliphi uhlobo le-niacin.
Izinhlobo Ezihlukile ze-Nicotinic Acid
I-Nicotinic acid, ekhonjiswe kwizifundo ukuba nomthelela omuhle kuphrofayela yakho ye-lipid, itholakala nangezinhlobonhlobo ezahlukene:
- Ukukhululwa ngokushesha (i-IR) i-nicotinic acid yindlela ye-nicotinic acid efaka igazi elilodwa ngesikhathi esisodwa. Nakuba uthola lo mlingo we-nicotinic acid ngesikhathi esifanayo, lokhu kungakwenza ube nemiphumela emibi kakhulu, njengokuhlwitha nokuhlushwa.
- Ukukhululwa okuqhubekayo (SR) i-nicotinic acid kukhishwe kancane kancane egazini futhi kunganciphisa ezinye zezinto ezingathandeki ezithinta i-nicotinic therapy.
- Ukukhululwa okwehlisiwe (ER) i-nicotinic acid nakho kukhishwe isikhathi esincane kodwa kuyatholakala kuphela ngomuthi odokotela.
Amandla we-Niacin Supplements aphephile
Ukubunjwa kwe-niacin okungaphezu kwamakhompiyutha kungahlukana ngamandla futhi kungaqukatha amanye amavithamini, amaminerali, namakhambi. Kubaluleke kakhulu ukuthi ubheke ilebula lomkhiqizi ebhodleleni mayelana nezinkomba zokuthi ungathatha kanjani umkhiqizo nezinye izithako ekugcineni ukuze uvikele imiphumela emibi-futhi kungenzeka ukulondoloze imali.
Umhlinzeki wakho wezezempilo angakusiza ukuba unqume ukuthi ingakanani umthamo ongayithatha nokuthi ungavimbela kanjani imiphumela emibi lapho uqala ukwelashwa kwe-niacin.
> Imithombo:
> Abaphenyi be-AIM-HIGH, iBoden WE, Probstfield JL, Anderson T, Chaitman BR, Desvignes-Nickens P, Koprowicz K, McBride R, Teo K, Weintraub W. Niacin ezigulini ezinamazinga aphansi e-HDL ama-Cholesterol athola ukwelashwa kwe-Statin ejulile. I-New England Journal of Medicine . 2011; 365 (24): 2255-2267. i-doi: 10.1056 / nejmoa1107579.
> Mackay D, Hathcock J, Guarneri E. Niacin: amafomu amakhemikhali, ukutholakala kwemvelo kanye nemiphumela yezempilo. Ukubuyekezwa kokudla . 2012; 70 (6): 357-366. i-doi: 10.1111 / j.1753-4887.2012.00479.x.
> Ukuphatha i-Blood Cholesterol kuBantu abadala: Ukubukezwa kobufakazi obuhle obuvela ku-Panel Expert Panel, 2013. I-National Heart, i-Lung ne-Blood Institute.
> Schandelmaier S, Briel M, Saccilotto R, et al. I-Niacin yokuvimbela okuyisisekelo kanye nokwesibili kwemicimbi yenhliziyo. I-Cochrane Database yezibuyekezo ezihleliwe . 2017. ini: 10.1002 / 14651858.cd009744.pub2.