Njengoba kunemiphumela emibi ye-niacin ehambisana nokuthatha imikhiqizo ye-nicotinic acid, ungase uthande ukusebenzisa i-noacin ye-flush, noma usule i-niacin yamahhala, ukuze unciphise i-cholesterol yakho.
Amafomu e-Niacin
I-Niacin , noma i-vitamin B-3, iyisekeli eliziwa ngekhono layo lokunciphisa i-cholesterol nokuvimbela isifo senhliziyo. Kunezinhlobo ezintathu ezinkulu ze-niacin ezitholakalayo emakethe: i-nicotinic acid, i-nicotinamide, ne-inositol hexaniacinate.
Zonke lezi zinhlobo ze-niacin zitholakala ngaphezu kwe-counter, noma ngokwazo noma zifakwe ku-multivitamin, ngokulingana okuhlukile.
I-Nicotinic acid yindlela ye-niacin ecwaningiwe kakhulu ngekhono layo lokunciphisa i-cholesterol. Eqinisweni, i-nicotinic acid iboniswe ukuthi ithinte zonke izici zephrofayili yakho ye- lipid : ingaveza i-lipoproteins ephezulu ("okuhle" i-cholesterol, i-HDL) kanye ne-lipoproteins ephansi (ukhwaliti "cholesterol", i-LDL) kanye ne- triglycerides .
Nakuba i-nicotinic acid ithinta zonke izingxenye zephrofayili yakho ye-lipid, ibuye ibonakale ngemiphumela yaso emibi kakhulu, efaka ukushaywa, ukuqhuma nokushisa okushisayo. Lemiphumela emibi ingenakubekezeleleka futhi iyisisusa esivame kakhulu ukusetshenziswa kwe-nicotinic acid kuphelile.
I-Flush-Free noma Ayi-Flush Niacin
I-nicotinic acid eyaziwa ngokuthi i-inositol hexaniacinate. I-niacin engenazimpukane ithola igama layo kusukela ekukhoneni kwayo ukunciphisa imiphumela emibi njenge-flushing ebonakala ngezinye izinhlobo ze-niacin.
Ngeshwa, akuyona into eyaziwa kakhulu nge-niacin engenamanzi, futhi abacwaningi bathola ukuthi ifomu layo elisebenzayo lingase lingangeni ngisho negazi. Ngakho-ke, akunakwenzeka ukuthi i-niacin engenamahlumela ehlisa i-cholesterol.
I-niacin engenamapulangwe inamakhemikhali ayisithupha e-niacin axhunyiwe ndawonye yi-inositol yamakhemikhali.
Kunconywa ukuthi, emzimbeni, leli khemikhali lidilizwe libe yi-nicotinic acid futhi lingena egazini. Njengoba le nqubo ithatha isikhathi eside, kuyacatshangwa ukuthi lokhu kuyimbangela yemiphumela yaso emibi. Kodwa-ke, uma inani eliphezulu le-niacin elingenalutho lingeniswa, ungase uzwe nemiphumela emibi ye-niacin.
I-niacin engenamapulangwe iyakwazi ukwehlisa imithwalo yegazi futhi isetshenziswe ukwelashwa kwezifo, ezifana nesifo sikaRaynaud . Ukuhlola ukusebenzisa i-nicotinic acid kuningi; Kodwa-ke, ukuhlola ukuhlola ukusebenza kwe-inositol hexaniacinate yedwa ekunciphiseni amazinga e-cholesterol kuncane.
Eqinisweni, kube khona ingxabano mayelana nokuthi i-niacin engenayo noma ayihluthuli yini ehlisa amazinga e-cholesterol - akuzange kube nezifundo ezanele zokusekela noma ukuphika lokhu. Ucwaningo olunye luye lwabonisa ukuthi kuze kufike ku-2,400 mg we-niacin engenamanzi ngosuku (ngokulinganisa okulinganiselwe) okudingekayo ukuze kunciphise amazinga e-cholesterol, kanti ezinye izifundo ziye zabonisa ukuthi i-niacin engenamanzi ayiphumeli ekunciphiseni i-cholesterol.
Ukuhlola okuphawulekayo ukuhlola izinhlobo ezahlukene ze-niacin kulinganisa inani lemali yama-nicotinic ekhululekile, i-niacin ehlisa i-cholesterol, etholakala egazini ngemva kokuba umkhiqizo usungisiwe.
Ucwaningo lwathola ukuthi ngemva kokuba kuthathwe ama-gram angu-1.6 e-inositol hexaniacinate, yi-0.6 micromoles / L kuphela ye-nicotinic acid eyatholakala egazini.
Uma kuqhathaniswa, ukuthatha igramu eyodwa ye-nicotinic acid ngokushesha-kukhishwe ama-micromoles angu-240 / L egazini ngenkathi ithatha amagremu amabili okukhululwa kwe-nicotinic acid okwenziwe ngokuqhubekayo kwaholela ekulinganisweni kwama-micromoles angu-31 / L egazi, okubili kokubili akwanele ukwehlisa i-cholesterol.
Ngakho-ke, nge-nicotinic encane kakhulu egazini elibonwe kulolu cwaningo, kanye nokuntuleka kobufakazi obonwe kwezinye izifundo, akungabazeki ukuthi i-niacin engenamanzi iyasebenza ekunciphiseni i-cholesterol.
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