Izinzuzo zezeMpilo, Ukusetshenziswa, nokuningi
I-Glucosamine iyinhlanganisela etholakala ngokwemvelo emzimbeni, eyenziwe nge-glucose kanye ne-amino acid glutamine. I-glucosamine iyadingeka ukukhiqiza i-glycosaminoglycan, i-molecule esetshenziselwa ukwakheka nokulungiswa kwe-cartilage nezinye izicubu zomzimba.
I-Glucosamine Sebenzisa i-Osteoarthritis
Njengoba ukukhiqizwa kwe-glucosamine kunciphisa iminyaka, abanye abantu basebenzisa izithako ze-glucosamine ukulwa nezimo zezempilo ezihlobene nokuguga, njenge- osteoarthritis .
Ukuthatha i-glucosamine njengengxenye yokudla okunomsoco kucatshangwa ukuthi kugcine i-osteoarthritis ekuhloleni ngokubuyisela ukuhlinzekwa kweglucosamine yomzimba nokulungisa i-cartilage ewonakele.
Glucosamine With Chondroitin noma MSM
I-glucosamine ivame ukuhlanganiswa ne-chondroitin sulfate, i-molecule ngokwemvelo ikhona ku-cartilage. I-Chondroitin inikeza u-cartilage elasticity futhi ikholelwa ukuthi ingavimbela ukubhujiswa kwe-cartilage nge-enzyme.
Kwezinye izimo, i-glucosamine iphinde ihlanganiswe ne-methylsulfonylmethane (noma i- MSM ) ekufakeni izondlo.
Ukusetshenziswa kwe-Glucosamine
Ngokwezinye izindlela zokwelapha, abagqugquzeli bathi i-glucosamine ingasiza ngezinkinga zempilo ezilandelayo:
- Isifo sikashukela
- I-cholesterol ephakeme
- Ukuvuvukala
- Isifo sesifo sofuba (njengesifo soccer ulcerative )
- I-osteoarthritis
- I-rheumatoid arthritis
- Isifo esihlangene se-Temporomandibular (esaziwa nangokuthi "TMD" noma "TMJ")
I-Science Behind Glucosamine
Ucwaningo lubonisa ukuthi i-glucosamine inganikeza izinzuzo ezithile zezempilo.
Nakhu ukubuka okufundwayo okufundwayo:
I-osteoarthritis
I-Glucosamine ingaba yinzuzo ekwelapheni i-osteoarthritis (ikakhulukazi i-osteoarthritis yamadolo), ngokusho kweNational Institutes of Health (NIH).
Ngempela, umbiko wango-2005 oshicilelwe kwiDatabase yeChrisrane Yokuhlola Okuhlelekile waphetha ngokuthi amanye amalungiselelo e-glucosamine anganciphisa ubuhlungu futhi asebenze kubantu abane-osteoarthritis.
Ngombiko, abacwaningi bahlaziya izifundo ezingu-20 (ngeziguli ezingu-2 570) ekusetshenzisweni kwe-glucosamine ekwelapheni i-osteoarthritis.
Kukhona nobufakazi bokuthi i-glucosamine inganciphisa ukuqhubeka kwe-osteoarthritis. Ngokwesifundo se-2002 esivela ku-Archives of Internal Medicine, isibonelo, abantu abangu-202 abanesifo se-osteoarthritis esine-mild-to-moderate bathatha ama-1,500 mg we-glucosamine noma i-placebo nsuku zonke iminyaka emithathu.
Ekupheleni kwalolu cwaningo, abacwaningi bathola ukuthi i-glucosamine yanciphisa ukuqhuma kwe-knee ostoarthritis nokunciphisa ubuhlungu nokuqina. Ngaphezu kwalokho, ama-X ray awazange aveze ushintsho olubanzi noma ukugxila kwezikhala ezihlangene emadolweni (isibonakaliso sokuwohloka) phakathi kwamalungu eqembu le-glucosamine. Ngokuphambene nalokho, izikhala ezihlanganyelwe kwabahlanganyeli be-placebo zancipha ngaphezu kweminyaka emithathu.
Esinye sezifundo ezinkulu kakhulu kwi-glucosamine ye-osteoarthritis kwakuyizingxoxo zenyanga ezingu-6 ezixhaswe yiNational Institutes of Health futhi zanyatheliswa eNew England Journal of Medicine ngonyaka ka-2006. Ebizwa nge-GAIT, ucwaningo lwaqhathanisa ukusebenza kahle kwe-glucosamine, i-chondroitin sulfate, inhlanganisela we-glucosamine ne-chondroitin sulfate, i-celecoxib yezidakamizwa, noma i-placebo kubantu abane-knee-osteoarthritis.
I-Glucosamine noma i-chondroitin yodwa noma inhlanganisela ayizange iyanciphise ubuhlungu eqenjini lonke, nakuba abantu abasesimweni esifundazo bebuhlungu obukhulu bokubukeka kwamadolo cishe bebengasabela ku-glucosamine.
Esinye isici esikhulu se-GAIT Trial kwaba ukuthi i-glucosamine hydrochloride yayisetshenziselwa esikhundleni se-glucosamine sulfate (uhlobo olusetshenziselwa kakhulu nokucwaninga lwe-glucosamine).
Ngombiko wango-2007 oshicilelwe ku-Arthritis neRheumatism, uphenyo bahlaziya ucwaningo olwedlule ku-glucosamine (kufaka phakathi i-GAIT Trial) futhi baphetha ngokuthi i-glucosamine hydrochloride ayiphumelelanga. Ukuhlaziywa kwaphinde kwathola ukuthi izifundo ze-glucosamine sulfate zazihluke kakhulu komunye nomunye futhi azizange zenziwe ngendlela efanele, ngakho-ke azikwazi ukudweba kahle. Ucwaningo olungaphezulu luyadingeka.
I-Osteoarthritis Joint Temporomandibular
I-Glucosamine kungenzeka isebenza kahle nge-osteoarthritis yama-temporomandibular, ngokusho kwe-NIH. Esifundweni sika-2001 esivela kuyi-Journal of Rheumatology, abacwaningi bathola ukuthi i-glucosamine yanciphisa ubuhlungu phakathi kweqembu labantu abadala abanalo nalesi simo.
Ukuze kuhlolwe, iziguli ezingu-45 zithatha i-glucosamine noma ibuprofen izinsuku ezingu-90. Kubantu abangu-39 abaqeda ukutadisha, amalungu angu-15 eqembu le-glucosamine namalungu angu-11 eqembu ibuprofen babonisa ngcono okukhulu.
Ubuhlungu Emuva Emuva
I-Glucosamine ingase ingabasizi abantu abanezinhlungu ezingapheli ezinqolobaneni eziphansi kanye ne-osteoarthritis ye-degenerative lermar, ngokusho kocwaningo lwango-2010 oluvela kuyi-Journal of the American Medical Association.
Ezinyangeni eziyisithupha, iziguli ezingu-250 zombili lezi zimo zithatha ama-glucosamine supplements noma i-placebo. Imiphumela yokufundwa yembula ukuthi i-glucosamine ayizange ihlise ubuhlungu obuphansi bokubuyela emuva noma ukukhubazeka okuhlobene nobuhlungu.
I-glaucoma
Ubufakazi obukhawulelwe kakhulu bubonisa ukuthi i-glucosamine ingaba ukwelashwa kwe- glaucoma , ngokusho kombiko we-2001 ovela ku-Alternative Medicine Review. Nokho, ngenxa yokuntuleka kokuhlolwa kokuhlolwa kwe-glucosamine yokusebenza kweglucosamine njengokwelapha kwe-glaucoma, kusheshe kakhulu ukutusa i-glucosamine njenge-glaucoma therapy.
Ukutholaphi i-Glucosamine
I-Glucosamine itholakala njengengxenye yokudla okunomsoco ezitolo zezokudla nezitolo eziningi zezidakamizwa. I-Glucosamine iphinde isetshenziswe kwezinye iziphuzo zezemidlalo naseziqhumini.
Ama-glucosamine supplements akhiqizwa ebhokisatri evela ku-chitin, into etholakala emagobolondo ama-shrimp, crab, lobster nezinye izidalwa zasolwandle.
Amapulangwe
Ucwaningo oluningi olubandakanya abantu luye lwabona ukuthi ukusetshenziswa okwesikhashana kwe-glucosamine kuvunyelwe kahle. Funda ngemiphumela emibi ye-glucosamine .
Izithako, ngokuvamile, azihloliswanga ukuphepha futhi zigcine engqondweni ukuthi ukuphepha kwezidakamizwa kwabesifazane abakhulelwe, omama abahlengikazi, izingane, nalabo abanezimo zezokwelapha noma abaphuza imishanguzo akuzange kusungulwe.
Ungathola amathiphu okuphepha ekusebenziseni izithako lapha , kodwa uma ucabangela ukusetshenziswa kwe-glucosamine, khuluma nomhlinzeki wakho oyinhloko wokunakekelwa kuqala.
Ukusebenzisa i-Glucosamine yezeMpilo
I-Glucosamine ingaba yinzuzo ethile kubantu abane-osteoarthritis. Kubalulekile ukuqaphela ukuthi abahlinzeki bezempilo bavame ukuphakamisa ukuhlolwa kwezinyanga ezintathu ze-glucosamine futhi beyeke uma kungekho ukuthuthuka ngemva kwezinyanga ezintathu.
Uma ucabangela ukusetshenziswa kwe-glucosamine ekwelapheni kwanoma yisiphi isimo, khuluma nodokotela wakho ngaphambi kokuqala isimiso sakho sosizo.
> Imithombo:
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> Inhloko KA KA. "Ukwelashwa Kwemvelo Yezinkinga Zama-Ocular, Ingxenye Yesibili: Isifo Sengqondo Ne-Glaucoma." I-Altern Med Rev. 2001 Apr; 6 (2): 141-66.
> Izikhungo Zikazwelonke Zempilo. "I-Glucosamine Sulfate: Ama-MedlinePlus Supplements". April 2011.
> Pavelka K, Gatterova J, Olejarova M, Machacek S, Giacovelli G, Rovati LC. Ukusetshenziswa kwe-Glucosamine Sulfate Nokunciphisa Ukuqhubekela phambili Kwe-Knee Osteoarthritis: Ukufunda Okungama-3, Okungahleliwe, Okulawulwa Kwendawo, UkuPhuphuka Okubili. 2002 Oct 14; 162 (18): 2113-23.
> Thie NM, Prasad NG, Major PW. "Ukuhlolwa kwe-glucosamine sulfate kuqhathaniswa ne-ibuprofen ekwelapheni i-osteoarthritis yokuhlangana kwe-temporomandibular. J Rheumatol. 2001 Jun; 28 (6): 1347-55.
> Towheed TE, Maxwell L, Anastassiades TP, Shea B, Houpt J, Robinson V, Hochberg MC, Wells G. "I-Glucosamine Therapy yokwelapha i-Osteoarthritis." Cochrane Database Syst Rev. 2005 Apr 18; (2): CD002946.
> Vlad SC, LaValley MP, McAlindon TE, Felson DT. Glucosamine for Pain ku-Osteoarthritis: Kungani Ukulingwa Kwemiphumela Kungavamile? I-Arthritis Rheum. (2007) 56.7: 2267-2277.
> Wilkens P, Scheel IB, Grundnes O, Hellum C, Storheim K. "Umphumela we-Glucosamine ngokukhubazeka okuhambisana nobuhlungu kubantu abaneziguli ezinezinkinga ezingapheliyo ezibuhlungu kanye nezidakamizwa ezibuhlungu ezenziwe yi-Lumbar Osteoarthritis." I-JAMA. 2010 Jul 7; 304 (1): 45-52.