I-Ankylosing Spondylitis

Okubalulekile kwe-Ankylosing Spondylitis

I-ankylosing spondylitis uhlobo lwe- arthritis elibhekene nokuvuvukala okungapheli okuthinta ngokuyinhloko emuva nangentamo (okungukuthi, umgogodla). Ezimweni ezimbi, amathambo emgogodini angase aqhubeke (okubizwa nangokuthi i-ankylosis) okwenza umgogodla oqinile futhi ongapheli kahle. Ukuma okungajwayelekile kungaba umphumela. Amanye amalunga angase ahileleke, kufaka phakathi izinqulu, amadolo, amaqaqa, noma amahlombe. Lesi sifo singase sihlangane nemiphumela yesistimu , sithinta izitho ezihlukahlukene zomzimba.

> Bona indlela i-spondylitis e-ankylosing, uhlobo lwe-arthritis, ethinta ngayo umgogodla.

I-anondlosing spondylitis ingokwesigaba sezimiso ezibizwa ngokuthi i- spondyloarthropathies . Amanye ama-spondyloarthropathies afaka:

• I-arthritis esebenzayo
• I-arthritis yengqondo
• I-arthritis ehambisana nezifo ezifuywayo zezifo (isifo sokulonda i-ulcerative noma isifo sikaCrohn)
• I-arthritis ye-enteropathic

I-Spondyloarthropathies ihlukaniswa njenge-axial noma i-peripheral, kuye ngokuthi yiziphi amalunga ahilelekile.

• Okudingeka Ukwazi Ngokuthola Ukuxilongwa Kwe-Anondlosing Spondylitis

• Ukwelashwa kwe-Ankylosing Spondylitis

I-Axial ibhekisela ekubandakanyekeni komgogodla. I-Peripheral ibhekisela kwamanye amalunga engaphandle komgogodla. I-ankylosing spondylitis iyi-spacyloarthropathy ye-axial.

Isizathu se-Ankylosing Spondylitis

Isizathu salesi simo asikwazi, kepha i- HLA-B27 ifulethi ikhona ngamaphesenti angu-90 abantu abanesifo, ephakamisa ukuxhumeka kofuzo. Noma kunjalo, kubalulekile ukuqaphela ukuthi akuwona wonke umuntu onesifo se-HLA-B27 okhulisa i-spondylitis e-ankylosing. Ngokusho kweSpondylitis Association of America, kungenzeka ukuthi izakhi zofuzo ezinhlanu noma eziyisithupha ezihileleke ekuthandweni kwe-ankylosing spondylitis. Abacwaningi bakholelwa ukuthi umcimbi obangela ukukhulelwa kwemvelo uhlangene nokukhunjulwa yilokho okubangela ukuthi lesi sifo sikhule.

Ubani othola i-Anondlosing Spondylitis?

Lesi simo sithinta kakhulu amadoda. Amadoda amabili kuya kathathu amadoda angaphezu kwabesifazane abakha lesi sifo. Noma kunjalo, noma ubani angakwazi ukuhlakulela i-anondlosing spondylitis. Isikhathi sokuqala kwesifo ngokuvamile siphakathi kweminyaka engu-17 no-35 ubudala. Ngokusho kwe-CDC (Izikhungo Zokwelashwa Nokuvimbela I-NHANES Yezifo), okungenani abantu abadala abayizigidi ezingu-2,7 e-US bane-spacyloarthritis ye-axial.

Izimpawu Ezihlobene Ne-Ankylosing Spondylitis

Izimpawu zokuqala ze-anondlosing spondylitis zivame ubuhlungu nokuqina esifundeni esingaphansi ngemuva. Izimpawu ngokuvamile ziqala ngaphambi kweminyaka engama-45. Ubuhlungu nokuqina kuguqukela futhi kuthuthuke zibe izimpawu ezingapheli. Ngokuvamile, ubuhlungu obunamaphilisi abuhlungu bukhumbuza ukuphumula okulandelayo noma ukungasebenzi futhi kuthuthukisa nomsebenzi. Kungabangela ukuqina kosa ekuseni okugcina imizuzu engaphezu kwengu-30.

Ubuhlungu nokuqina, ngokuhamba kwesikhathi, kungathuthuka umgogodla entanyeni. Amathambo omgogodla nentamo angase aqhubekele, enze ukuhamba okulinganiselwe futhi ahlehlise ukuguquguquka komgogodla.

Njengoba sekushiwo kakade, amahlombe, izintambo, namanye amalunga angabandakanyeka. Ubuhlungu be-Hip buvame kakhulu nge-anondlosing spondylitis futhi kungahle kuhlotshaniswe nobuhlungu ku-groin noma emathangeni, kanye nobunzima bokuhamba. Uma kubanjwe umhlanga wezintambo, ukwandiswa kwesifuba okungavamile kungabangela ubunzima bokuphefumula. Ama-tendon kanye nemigqa ingathinteka (isb., Ukubandakanyeka kwesithende ne- Achilles tendonitis kanye ne- plantar fasciitis ).

I-ankylosing spondylitis iyisifo se-systemic, okusho ukuthi abantu bangase bahlakulele umkhuhlane, ukukhathala, iso, noma ukuvuvukala kwesibilini. Ukubandakanyeka kwenhliziyo noma yamaphaphu akuvamile kodwa kungenzeka.

Ukuxilongwa kwe-Ankylosing Spondylitis

Ukuxilongwa ngokuyinhloko kusekelwe ezimpawu, ukuhlolwa ngokomzimba, ukuhlolwa kwegazi, nokuhlola izithombe. Izimpawu zokuqala ze-spondylitis e-ankylosing zingalingisa ezinye izimo, ngakho-ke izivivinyo zokuxilonga zisetshenziselwa ukulawula ezinye izifo ze-spondyloarthropathies nezinye izifo ze-rheumatic . Ukungabikho kwesifo sofuba kanye nama- nodules we-rheumatoid kusiza ukuhlukanisa phakathi nesifo samathambo .

Nakuba kungekho ukuhlola okukodwa kwegazi okungahlolisisa ngokucacile ukuthi i-spondylitis e-ankylosing, ukuhlolwa kwe-HLA-B27 inikeza inkomba ebalulekile yokuxilonga, ikakhulu emaqenjini athile abantu. Isibonelo, i-ankylosing spondylitis ingukuthi ukuxilongwa okungenakwenzeka kumuntu omhlophe, wezwe laseYurophu, futhi okungahambi kahle nge-HLA-B27. Izivivinyo zokuvuvukala okungavamile ( izinga lokudabuka kanye ne- CRP ) ziwusizo ekwenzeni isithombe somtholampilo, kodwa asihlolisi.

Ukucwaninga izici zesifundo se-ankylosing spondylitis shintsha izinguquko ezinhlangothini ze- sacroiliac . Ngenkathi izinguquko zingabonakala kuma-ray-ray, kungathatha iminyaka emva kokuqala kwezimpawu ukubonakala. I-MRI ingabuye isetshenziselwe ukubheka ukuthi izici zishintsha kumalungu e-sacroiliac. I-X-rays isetshenziselwa ukuhlola ubufakazi bokulimala emgodini.

Ukwelashwa kwe-Ankylosing Spondylitis

Ukwelashwa kwalesi simo ngokuyinhloko kugxile ekwehliseni ubuhlungu, ukuqina, nokuvuvukala. Ukuvimbela ukukhubazeka, ukugcina umsebenzi, kanye nokuqeqesha ukuqeqeshwa kuyimigomo yokwelashwa.

• I-Axial Spondyloarthritis ne-Ankylosing Spondylitis ihlobene kanjani?

• Ziyini Izimpawu Ze-Ankylosing Spondylitis?

Imithi esetshenziselwa ukwelapha i-ankylosing spondylitis ihlanganisa okulandelayo:

• Izidakamizwa ezingezona ukuvuvukala (ama-NSAID) yiyona ndlela yokuqala yokwelashwa kwe-pharmacologic. Abantu abaningi basebenzisa imithi ye-NSAID kuphela ukuze bayiphathe.
• Ama-analgesics noma imithi yobuhlungu ingasetshenziswa uma ubuhlungu bungalawulwa kahle yi-NSAID kuphela.
• I-TNF-blockers (i- Humira (i-adalimumab) , i- Remicade (i-infliximab) , i- Enbrel (etanercept) , i- Cimzia (certolizumab pegol) , ne- Simponi (golimumab) ivunyelwe ukuphatha i-spondylitis e-ankylosing futhi ibonise ukuthuthukiswa okukhulu emisebenzini yesifo.
• I-Cosentyx (secukinumab) , i-IL-17 inhibitor, yavunywa nje ngoJanuwari 2016 ngesimo.
• Ama-DMARD (izidakamizwa eziguqulwa izifo-anti-rheumatic) zingasetshenziswa ukunciphisa ukuqhubeka kwesifo. Ngokuvamile, i- sulfasalazine isetshenziselwa iziguli ezingenayo i-spondylitis ene-arthritis ye-peripheral engakwazi ukusebenzisa i-blocker ye-TNF. I-Methotrexate yedwa ingasiza abanye abantu, kodwa ngokuvamile akubhekwa njengendlela ephumelelayo ku-ankylosing spondylitis. Enye i-DMARD, i- Arava (i-leflunomide) , ithathwa njengenenzuzo encane noma engekho.
• Ama- corticosteroids omlomo ayasetshenziswa kaningi, kodwa uma ethathwa, kufanele kube yisikhathi esifushane, hhayi isikhathi eside.

Ukwelapha umzimba nokuzivocavoca kuyisici esibalulekile kunoma yiluphi uhlelo lwezokwelapha lwe-ankylosing spondylitis. Ukubaluleka kokuzivocavoca, njengengxenye yokuphatha lesi sifo nokulondoloza ukuhamba nokusebenza, akunakwenzeka.

Ukubikezelwa kwe-Ankylosing Spondylitis

Abanye abantu abanesimo sinenkinga yezifo ezincane futhi bayakwazi ukusebenza futhi basebenze ngokujwayelekile. Abanye bakhula izifo ezinzima futhi bahlala nemingcele eminingi ngenxa yesifo se-axial. Abanye abantu abane-spondylitis e-ankylosing bathuthukisa izinkinga ezingezona ezingozini zokuphila-kodwa akunjalo nakakhulu.

Ngokuvamile, isiguli ngasinye sibhekana nomsebenzi wesifo oguqukayo, okuyingxenye enkulu, ephathekayo. Mayelana namaphesenti angu-1 abantu abanesifo ngempela bafinyelele esiteji lapho izimpawu ziyancipha futhi zibhekwa njengokukhululwa.

Qaphela lezi zinto

Umgogodla owenziwe, noma ongaguquguquki kakhulu, uyingozi kakhulu. Lokho kusho, kufanele ukhumbule ingozi eyengeziwe futhi uthathe izinyathelo zokuqapha. Kumele ulinganise noma ugweme noma yikuphi ukuziphatha okungakwandisa ingozi yokuwa. Lokhu kungabandakanya noma yini ekunciphiseni inani lophuza utshwala obuthelayo ukufaka imishayo yokubamba futhi uqoqa uphonsa amathrekhi endlini yakho. Gwema umsebenzi ophezulu. Ngokuyinhloko, sebenzisa umqondo ovamile futhi ube yisivikelo somgogodla wakho.

Kufanele usebenzise umcamelo obeka intamo yakho bese ubuyela ngokuvumelana kahle ngenkathi uphumula noma ulala. Njalo sebenzisa ibhande lakho lesikhathi lapho ushayela noma njengomgibeli emotweni. Futhi, abantu abane-spondylitis e-ankylosing abashayayo bayacelwa ukuba bayeke ukuze banciphise ingozi yokuphefumula. Futhi ungakhohlwa ukubaluleka kokuhlanganyela iqhaza ohlelweni lokuzivocavoca ukuqinisa umgogodla wakho nokuthuthukisa impilo yakho ehlangene jikelele.

Izwi elivela

Ukuphila kahle nge-anondlosing spondylitis kuyoxhomeka ebubini besifo sakho, kanye nokuthi uzibophezele kangakanani ohlelweni lwakho lokwelapha, ukuvivinya umzimba njalo, nokuvikela umgogodla wakho. uye wakunikeza amaqiniso ayisisekelo mayelana nesimo futhi ungumthombo ongabuyela emuva kumacebiso okuphatha isifo oyidingayo.

> Imithombo:

> I-Ankylosing Spondylitis. I-Spondylitis Association of America. Kufinyelelwe ngo-07/16/2016.

> I-Spondyloarthritis. Umtholampilo waseCleveland. 11/04/2014.

> Van der Linden S et al. I-Ankylosing Spondylitis. I-Kelley's Bookbook of Rheumatology. Isahluko 75. Elsevier. Umagazini wesishiyagalolunye.

> Yu DT. Ukuhlola nokuphathwa kwe-Ankylosing Spondylitis kubantu abadala. Kusesikhathini. 04/21/2016.

> Yu DT. Ukwaziswa kwesineke: I-Ankylosing Spondylitis nezinye i-Spondyloarthritis (Ngaphandle Kwezinto Eziyisisekelo). Kusesikhathini. Kubuyekezwe i-04/12/2016.