I-Arthritis Psoriatic

Okubalulekile kwe-Psoriatic Arthritis

I-arthritis ye-Psoriatic iyinhlobo yokuvuvukala kwe-arthritis ehambisana ne-psoriasis (isimo sesikhumba) nezibonakaliso ezingavamile ezingavamile. Izimpawu ze-psoriasis nokuvuvukala okuhlangene ngokuvamile zikhula ngokuhlukile. Ezingamaphesenti angu-85 zabantu abanesifo, izimpawu ze-psoriasis zandulela izimpawu ze-arthritis. I-arthritis iqala ngaphambi kwe-psoriasis ngamaphesenti angaba ngu-15 alabo abane-arthritis ye-psoriatic.

> Ukubuka i-psoriatic arthritis ngeminwe nangaphambili.

Ngokusho kwe-CDC, abantu abadala abayizigidi ezingu-6.7 e-United States bane psoriasis. Kubantu abane psoriasis, amaphesenti angaba ngu-15 akha i-psoriatic arthritis. Ukuqhathaniswa kwalo okungaziwa, kodwa kulinganiselwa ukuthi kuphakathi kwamaphesenti angu-0.3 kuya ku-1 amaphesenti wabantu. Ukuqala kwe-arthritis ye-psoriatic ngokuvamile kuphakathi kweminyaka engu-30 no-50 ubudala, kodwa ingaqala noma kunini. Amadoda nabesifazane baphathelene ngokufanayo.

• Okufanele Ukwazi Ngo-Otezla (Apremilast)

• I-Stelara Iyisidakamizwa Esinayo I-Plaque Psoriasis ne-Psoriatic Arthritis

Izimpawu Ezihlobene Ne-Arthritis Psoriatic

Izimpawu ezihambisana ne-psoriatic arthritis ziyahlukahluka kanjani ukuthi zenzeka kanjani nokuthi yiziphi amalunga ezithintekayo. Noma yikuphi ukujoyina emzimbeni kungathinteka ubuhlungu nokuzwelana. Kungase kube nobunzima nobunzima ukuhambisa amalunga afintekile ngokuhamba kwawo okuvamile. Abanye abantu abanesifo sokuqina kwesifo ekuseni esihlala isikhathi esingaphezu kwesigamu sehora. Uma i-psoriasis ihilelekile, kunezintambo ezibomvu, ezikhukhulayo, ezikhulayo noma ezikhazimulayo zesikhumba. Ukungafani kwezipikili kungase kubonakale sengathi kufakwe futhi kugxilwe noma kukhishwe izinhlamvu. Ezinye izimpawu ezivamile ezihambisana ne-psoriatic arthritis zibandakanya ukukhathala, iminwe enesibindi evuvukale nezinyosi (dactylitis), i- tendinitis , i-enthesitis, ubuhlungu be-back back , kanye ne- conjunctivitis .

• Izimpawu Nezibonakaliso Ze-Psoriatic Arthritis

Izinhlobo ze-Psoriatic Arthritis

I-arthritis yengqondo iyingxenye yezimiso ezibizwa ngokuthi i- spondyloarthropathies . Kunezinhlobo ezinhlanu ezihlonziwe ze-arthritis ye-psoriatic ezihlukaniswa yizimpawu zabo. Izinhlobo eziyisihlanu, ezingase zenzeke, ziyi:

• I-Symmetric Psychiatric Arthritis ithinta amalunga ezinhlangothi zombili zomzimba (isib., Amadolo womabili, zombili izinqulu), futhi ngokuvamile ihlasela amalunga amaningi (i-polyarthritis) . Ifana ne- arthritis ye-rheumatoid kodwa ngokuvamile isisindo esinokukhubazeka okuncane. Amaphesenti angaba ngu-25 wezilwane ze-psoriatic arthritis analo hlobo lwesifo.
• I-Asymmetric Psoratic Arthritis ayithinti amalunga afanayo emaceleni omzimba. Noma yikuphi ukuhlanganyela kungathinteka, noma kunjalo. Ukubukeka okunjenge-sausage yeminwe nezinzwani kuvamile. Amajoyina angabomvu, afudumele, avuvuke futhi abuhlungu. Ngokuvamile kubhekwa uhlobo oluthile lwe-psoriatic arthritis, lungase lukhubaza kwabanye abantu. Cishe amaphesenti angu-80 abantu abane-arthritis ye-psoriatic abathinteka yilolu hlobo lwesifo.

• I-Distal Interphalangeal Predominant (DIP) I-Psoriatic Arthritis ibhekwa ngokuthi "uhlobo lwama-classics," ngokusho kwe-National Psoriasis Foundation, nakuba kwenzeka ngamaphesenti angaba ngu-5 kuya kwangu-10 kuphela alabo abane-arthritis ye-psoriatic. Izici eziyinhloko zalolu hlobo lwe-arthritis ye-psoriatic zibandakanya izingxenyana ezihlukanisayo zeminwe nezinzwane (okuhlanganyelwe eduze kwe-nail), kanye nobufakazi bezinguquko ze-nail.
• U-Spondylitis Uhlobo lwe-Psoriatic Arthritis lunokuvuvukala komgogodla njengesibonakaliso esiyinhloko. Amaphesenti angaba ngu-5 ukuya kwangu-20 abantu abane-arthritis ye-psoriatic abathintekayo nohlobo lwe-spondylitis. Cishe ingxenye yengxenye ye-spondylitis i- HLA-B27 , i-genetic marker.
• I-Arthritis Mutilans Uhlobo lwe-Psoriatic Arthritis lubhekwa njengento enzima, ekhubaza futhi engavamile. Ngaphansi kwamaphesenti amahlanu abantu abane-arthritis ye-psoriatic bayathinteka. Ukukhubazeka okuhlangene kubonisa i-arthritis mutilans ngamalungu amancane ezandla nezinyawo ezithinteka kakhulu. Ubuhlungu bezinyosi nobuhlungu obuphansi emuva buhlobene nalolu hlobo lwe-arthritis ye-psoriatic.

Ukuxilongwa kwe-Psoriatic Arthritis

Akukho ukuhlolwa okulodwa okusetshenziselwa ukuxilonga i-psoriatic arthritis. Ukuhlolwa ngokomzimba, ama-x-rays, ne-MRI asetshenziselwa ukusiza ukudala ukuxilongwa. Ukuhlolwa kwegazi kusetshenziselwa ukulawula ezinye izinhlobo ze-arthritis ezinezimpawu ezifanayo, njenge-arthritis ye-rheumatoid, i-gout, i- arthritis esebenzayo , i- anondlosing spondylitis , ne- osteoarthritis .

Nakuba ezinye izici ze-arthritis ze-psoriatic zifana nezinye izinhlobo ze-arthritis, izilonda zesikhumba, ukungafani kwezipikili, namaphethini wokuvuvukala kuyahlukanisa nezinye izinhlobo zokuvuvukala kwamathambo. Ngokushesha uma ukuxilongwa kuqinisekiswa udokotela, ukwelashwa okufanelekayo kungaqala. Ukuxilongwa kokuqala kanye nokwelashwa kokuqala kubalulekile ukuletha lesi sifo ukulawula, okuhlinzeka ithuba elihle lokuvimbela ukukhubazeka, ukuqhubeka kwezifo, nokulimala okuhlanganyelwe okuhlala njalo.

• Ukuhlola nokuxilongwa kwe-Psoriatic Arthritis

Ukwelashwa kwe-Psoriatic Arthritis

Ngoba i-arthritis ye-psoriatic ihilela kokubili ukubonakala kwesikhumba kanye nokubonakaliswa okuhlangene, ukuhloswe kwanoma yiluphi uhlelo lwezokwelapha kufanele lube nokugxila kokubili.

• I-Cosentyx: Option Treatment for Ankylosing Spondylitis ne-Psoriatic Arthritis

• Izinguquko Zesidlo Kungasiza Ukuphatha I-Psoriatic Arthritis

I-rheumatologist yakho izobheka ubuhlungu besifo lapho ukhetha ukwelashwa, kanye nokucabangela umphumela ongase ube khona wezokwelapha ezithile kwezinye izici zesifo. Isibonelo, ingabe imithi ekhethwe ukuphatha izimpawu ze-arthritis isiza noma ilimaze izici zesikhumba se-psoriatic arthritis? Ukwelashwa okunye nakho kuyisici ekukhetheni ukwelashwa.

Ngokuvamile, ama-NSAID (izidakamizwa ezingavimba ukuvuvukala) ayimithi yokuqala yokuthola abantu abanezimpawu zamathambo ezinobungozi obuphansi. Kulabo bantu abanezimpawu ezincane ezibangelwa isifo samagciwane , abangaphenduli kahle kuma-NSAID kuphela, ama-DMARD (izidakamizwa zokuguqula izifo) , njenge methotrexate noma i- Arava (leflunomide) , ingasetshenziswa. Izidakamizwa ze-biologic , njenge- block block TNF , zifanele abantu abanezifo ezinzima (isb., Ubufakazi bokukhulelwa, amalunga amaningana ashintshiwe, umkhawulo osebenzayo kakhulu). I-Corticosteroids ayisetshenziselwa i-psoriatic arthritis.

Uma izimpawu zesikhumba zivelele, mhlawumbe ezinzima kakhulu njengezimpawu ezihlangene, imithi engakwazi ukulawula kokubili ingcono kakhulu. I-TNF blockers ithathwa njengokwelashwa okuphumelelayo kokubili izici zesikhumba kanye ezihlangene ze-psoriatic arthritis. I-Methotrexate, photochemotherapy, i-PUVA, i-retinoic acid, ne-cyclosporine A ingasiza kokubili ukubonakaliswa kwesikhumba nokuhlanganyela.

Kunezidakamizwa ezintsha ezitholakalayo ze-psoriatic arthritis ezingase zicatshangelwe, futhi:

• I-Otezla (apremilast)
• I-Cosentyx (secukinumab)
• I-Stelara (ustekinumab)

Ukuthola Ukulawula I-Psoriatic Arthritis

Ngokuthakazelisayo, ngesikhathi esisodwa, i-psoriatic arthritis yayicatshangwa ukuthi iyisifo esincane. Eqinisweni, i-psoriatic arthritis inzima nakakhulu kunalokho okucatshangwa ekuqaleni. Ukuvumelana kwezincwadi zesayensi kuye kwembulani ukuthi, ngokuphathelene nokulimala okuhlangene okuqhubekayo, ukubikezela okubi kakhulu kuhlobene nalokhu:

• Inombolo ephakeme yamajoyina ane-inflammation esebenzayo
• Isilinganiso sedimentation ephakanyisiwe kanye ne- CRP
• Umonakalo ohlangene ubonakala kuma-x-ray
• Ukuhluleka ukuthola impendulo eyanele ngemithi ethile
• Ukulinganiselwa okusebenzayo
• Ikhwalithi engafanele yokuphila

Ukuthola ukulawula i-psoriatic arthritis, kubalulekile ukuba uhlolwe, uhlolwe futhi uphathwe yi- rheumatologist . Abantu abane-arthritis ye-psoriatic abathola ukwelashwa okusheshayo banethuba elihle lokulawula ukukhula kwesifo kanye nokulimala okuhlangene. Kuyaziwa ukuthi i-psoriatic arthritis ihlotshaniswa ne-comorbidities, ingozi eyengeziwe yokwehluleka, nokunyuka kokufa-esinye isizathu sokuthi ukwelashwa kokuqala kubalulekile.

• Izinkinga ze-Arthritis Psoriatic

Ukuphatha i-psoriatic arthritis ngempumelelo kudinga ukuba uhambisane nokuhlelwa kwemithi yakho, ukuvivinya umzimba, ukusebenzisa amasu okuvikelwa okuhlangene, ukulondoloza isisindo sakho esihle, nokulawula ukuxilongwa (isib. Isifo senhliziyo).

Izwi elivela

I-arthritis ye-Psoriatic ibizwa ngokuthi i-arthritis engavamile yokuvuvukala ngenxa yokuhlangana kwayo ne-psoriasis. Lokho, kanye nezinkinga ezingase zibe khona kanye nezimo ezihambisana ne-comorbid, zenza kubalulekile ukuthi ukwelashwa okuphumelelayo kuqhubeke ngokushesha. Umgomo wabantu abane-arthritis ye-psoriatic ukuphatha kahle lesi sifo futhi ulinganise umthelela wayo emgangathweni wokuphila. Ku-, sikunikeze amaqiniso okudingayo ukwazi nge-arthritis ye-psoriatic. Lolo lwazi luzokuvumela ukuba uqondise iziqondiso zakho, ukuxazulula imibuzo ukubuza udokotela wakho, nokukhuthazwa yizinketho zokwelashwa eziphumelelayo, kufaka phakathi ezinye izinto ezintsha.

> Imithombo:

> Gladman DD et al. I-Arthritis Psoriatic: i-epidemiology, izici zokwelapha, inkambo, nomphumela. Ama-Annal of the Rheumatic Disease. 2005; 64: ii14-ii17

> I-Gladman DD ne-Ritchlin C. Ukubonakaliswa kweMitholampilo nokuHlola kwe-Psoriatic Arthritis. Kusesikhathini. Kubuyekezwe 02/12/16.

> I-Gladman DD ne-Ritchlin C. Ulwazi Lomguli: I-Psoriatic Arthritis (Ngaphandle Kwezinto Eziyisisekelo). Kusesikhathini. Kubuyekezwa 04/13/16.

> Helmick CG et al. Ukuqhathaniswa kwe-Psoriasis Phakathi kwabantu abadala eMelika 2003-2006 no-2009-2010 National Health and Nutrition Examination Surveys . I-American Journal of Medicine Prevention . 2014.

> I-Psoriatic Arthritis, i-American College of Rheumatology. September 2013.