Indlela i-RTMS engase ikwazi ukuphatha ngayo i-Dementia
Ukuguqulwa Kwama-Transcranial Magnetic (TMS) yindlela entsha kakhulu yokusebenzisa i-magnetism ukuze ithinte ubuchopho. Akuyona into engavamile, okusho ukuthi inqubo ayidingi uhlobo lokuhlinzwa; kunalokho, kuqhutshwa ngokudlulisela izimpande zamagnetic ngokusebenzisa ubuchopho ngokucindezela umshini ngokumelene nekhanda. Kungenzeka yini ukuthi le nqubo efana nesayensi-fiction ingasiza abantu abane-Alzheimer's disease?
Ngokuvamile, i-TMS ifundwe njengendlela yokuphatha ukucindezeleka okungeke kuphendule imithi yokucindezeleka noma ukwelulekwa kokwelapha. Ucwaningo oluthile lwenziwe futhi lubonise i-TMS ukuba iphumelele kakhulu ekunciphiseni izinga lokucindezeleka kubantu abangaphenduli emithini.
I-TMS isacwaningwa okwamanje ezinhlokweni ezihlukahlukene, kuhlanganise ne- Alzheimer's , i- Parkinson , isifo , ukucindezeleka, ukukhathazeka okucindezelayo nokucindezela nokuningi, ngezinga elihlukile lokuphumelela.
Iyini i-TMS ephindaphinda?
I-TMS ephindaphinda (i-rTMS) lapho uchungechunge lwe-TMS lwenziwa ngokuhamba kwesikhathi.
Izifo ze-TMS ne-Alzheimer's
I-TMS, ikakhulukazi i-TMS ephindaphinda (i-rTMS), iye yacwaningwa njengendlela yokungenelela kubantu abane-Alzheimer's disease. Ucwaningo oluthile luye lwahlola umphumela we-TMS kubantu ababenokukhubazeka kokusebenza kwengqondo, kungakhathaliseki ukuthi yi- mental dementia , i-Alzheimer's, ukukhubazeka okunengqondo noma ezinye izinhlobo zokucindezeleka komqondo .
Ngokuvamile, ukusebenzisa i-rTMS kuhlangene nokuqeqeshwa kwengqondo esikhathini esingamaviki ambalwa, ngokuhlolwa kwenziwa ngaphambi kwe-TMS nokuqeqeshwa kwengqondo, ingxenye yokuhamba, ekupheleni kwezinyanga eziningana kulandela i-TMS nokuqeqeshwa kwengqondo.
Izifundo zocwaningo
Abacwaningi benza ucwaningo oluncane olubandakanya abahlanganyeli abayisishiyagalombili abathola ama-RTMS kanye nokuqeqeshwa kwengqondo nsuku zonke amasonto ayisithupha bese kabili ngeviki ezinyangeni ezintathu ezizayo.
Ukusebenza komqondo kwabahlanganyeli kwahlolwa ngaphambi kokuqala kokutadisha, emasontweni ayisithupha ukuya ekutadisheni nasezinyangeni ezine nengxenye ngemuva kokuqala kocwaningo. Izibalo ezitholakala ku- Alzheimer's Scale Assessment Scale-Cognitive zazithuthukiswa ngamaphuzu angaba ngu-4 kokubili emasontweni ayisithupha ekutadisheni nasekupheleni kwenyanga ezine nesigamu.
Ezinye izifundo eziningana ezibandakanya ukusetshenziswa kwe-rTMS kuphela ngaphandle kokuqeqeshwa kokucabangisisa kuye kwaqhutshwa nemiphumela emihle. Ngemuva kokuthola i-RTMS, abahlanganyeli ezifundweni ezihlukahlukene babonise ukuthuthukiswa kokuqonda kwemisho yokuhlola, ukubiza amagama, nokwenza okuthile okubiza igama.
Ucwaningo oluthile lwathola ukuthi labo abanesifo sengqondo sokuqala kwengqondo babonisa ukuthuthukiswa okungcono kunokwabantu abanesiteji esiphakathi noma ukuwohloka komqondo okude kwesikhathi .
Kuze kube manje, akukho miphumela emibi kakhulu ebonakalayo, futhi izinzuzo ziboniswe kubantu abanomzimba omncane (isigaba sokuqala), okulinganiselwe (esiteji esiphakathi) nesifo esinzima se-Alzheimer's.
I-TMS njengethuluzi lokuxilonga?
Olunye ucwaningo luye lwabona ukuthi i-TMS ingase ibe yindlela enembile, engavumelekile yokuthola isifo se-Alzheimer futhi ihlukanise nokucindezeleka kwe-frontotemporal kanye nabahlanganyeli abacwaninga bezempilo abavamile.
Kudingeka Amacala Omtholampilo Oqhubekayo
Kubalulekile ukuqaphela ukuthi ukutadisha okwengeziwe kuyadingeka, njengoba lezi zifundo nge-rTMS zibandakanye izinombolo ezincane zabahlanganyeli futhi zihlelwe isikhathi esifushane. Kunezivivinyo eziningi zokwelashwa eziqhubekayo njengamanje ukuze ziqhubeke nokucwaninga okubandakanya i-rTMS. Ungabuka lezo zivivinyo zemitholampilo e-clinicaltrials.gov futhi useshe ngaphansi kwe-"transcranial magnetic stimulation Alzheimer" noma uvakashele i-TrialMatch, isevisi etholakala nge-Alzheimer's Association.
Izwi kusuka
Imithi yokwelapha i-Alzheimer's nezinye izinhlobo zokudemeka kwengqondo ziye zalinganiselwe ekusebenzeni kwazo.
Ziza nemiphumela emibi, ezinye zazo ziphawuleka kakhulu. Ukuvuselela okuphindaphindiwe kwe-magnetic ukukwazi ukuthuthukisa ukuqonda futhi ukwandise ukusebenza kwansuku zonke ngaphandle kwengozi yemiphumela emibi kakhulu.
Imithombo:
I-Beth Israel Isikhungo Sezokwelapha Se-Deaconess .: Isibhedlela Sokufundisa se-Harvard Medical School. Ukuguqulwa Kwe-Transcranial Direct Current. http://www.bidmc.org/CentersandDepartments/Departments/Neurology/NoninvasiveBrainStimulation/OLDTMS/TranscranialDirectCurrentStimulation.aspx
I-European Journal ye-Neurology. 21 MAR 2012. I-Prefrontalcortex i-rTMS ithuthukisa isenzo esiqhamukayo ekuqhakambeni okuqhubekayo okungahambisani ne-aphasia.
I-European Journal ye-Neurology. 15.12 (Dec. 2008): p1286. Ukuvuselela kwamagnetic ukudluliswa kwamandla kugcizelela ukuqamba ngeziguli ezigulini zezifo ze-Alzheimer ngezigaba ezahlukene zokuncipha kwengqondo.
I-International Journal yeSifo Se-Alzheimer. Izimo zokukhuthazwa kwe-Transcranial Magnetic ku-Alzheimer's. http://www.hindawi.com/journals/ijad/2011/263817/
I-Journal ye-Neural Transmission. 2011 Mar; 118 (3): 463-71. Umthelela omuhle wokuphindaphindiwe ukuvuselela amandla omzimba okuhlanganisa ukuqeqeshwa kwengqondo yokwelashwa kwesifo se-Alzheimer: ubufakazi bokufunda isifundo. http://www.ncbi.nlm.nih.gov/pubmed/21246222?dopt=AbstractPlus
> Lee, J., Oh, E., Sohn, E. no-Lee, A. (2017). UKUQALA KWAMAGNETIC OKUPHAKATHI OKUHLELEKILEYO OKUQHELEKILE UKUQEQESHA OKUQHELEKILE NGOKWESIKHATHI SE-ALZHEIMER .
Uhlelo lwe-Psychiatric Neurotherapeutics (PNP). Isibhedlela saseMcLean. I-Harvard Medical School Yokubambisana. Ukukhuthazwa Okumangalisayo Kwe-Transcranial Magnetic (TMS). http://www.mcleanhospital.org/programs/transcranial-magnetic-stimulation-tms-service