Ezimweni eziningi, umehluko phakathi kwe- atopic dermatitis no- contact dermatitis kusobala. Kwezinye izimo, akusobala. Ezinye iziguli zingaba nazo zonke zombili ezingeni eliphezulu futhi zixhumana no-dermatitis ngesikhathi esifanayo, okuyinto enzima kakhulu ukuyihlola. Nakuba kunezimo eziningi ezifanayo phakathi kwalezi zimo ezimbili ezivamile, kunezinto ezihlukile ezibalulekile ikakhulukazi uma kuziwa ezimbangela ze-dermatitis.
Ukufana Phakathi kwe-Atopic ne-Contact Dermatitis
Kokubili i-atopic ne-contact dermatitis yizinhlobo ze- eczema . I-eczema ayitholakali. Kunalokho, i-eczema ibhekisela ekugqibeleni okwenzekayo ngenxa yalezi zimo. Ngokuvamile kunezigaba ezintathu ezahlukene ze-eczema:
- I-eczema enhle ibhekwa ngamabhansela amancane (ama-vesicles) esikhumba esikhulayo, esibomvu.
- I-eczema encane yilezi zinhlamba, ezomile, ezinamakhaza, ezikhukhulayo, noma ezikhukhulayo.
- I-eczema engapheli ibonakala ngokucwiliswa, ukuqina kwesikhumba esikhumbeni esenziwa ngenxa yokutshala okungapheli.
I-biopsy yesikhumba kokubili i-atopic neyokuxhumana ne-dermatitis izobonisa izici ezifanayo-okungukuthi ushintsho lwe-epidermis, ukuvuvukala kwamaseli esikhumba e-epidermal avela njengesiponji ngaphansi kwe-microscope. Ngakho-ke, i-biopsy yesikhumba ngeke ihlukanise phakathi kwalezi zimo ezimbili.
Umehluko Phakathi kwe-Atopic ne-Contact Dermatitis
Kukhona umehluko obalulekile phakathi kwe-atopic ne-contact dermatitis, okubaluleke nakakhulu ukubekwa komuntu ukuthuthukisa isimo.
Umuntu onesifo se-atopic dermatitis uvame ukushintshashintsha kwezakhi zofuzo kumaprotheni esikhumbeni sabo esibizwa ngokuthi i-filaggrin.
Ukuguqulwa kwe-filaggrin kubangela ukuphazamiseka kwezithiyo phakathi kwama-cell skin epidermal. Lokhu kuholela ekukhuculeni kwesinye isikhumba kanye nokukwazi ukuthola ama-aerallergens, njenge-pet dander nezidakamizwa, ukuze ungene esikhunjeni.
Ama-aerallergens anjalo abangela ukuvuvukala kwe-allergen nokuzwa okunamandla okubamba. Ukukhipha kungaphazamisa isikhumba futhi kubangele ukuvuvukala nokubamba ngaphezulu.
Isisindo esiyinhloko sokungalingani kahle singabangela futhi ukuthi i-eczema ithuthuke njengomphumela wokudla ukudla umuntu ayenakho ukugula, okwenza ukuthi i-T-lymphocytes (uhlobo lwegciwane legazi elimhlophe) libuyele esikhumbeni futhi liholele ukuvuvukala kwe-allergen . Ngaphandle kwalezi zinto ezibonakalayo, umuntu akakwazi ukuthuthukisa i-dermatitis ye-atopic.
Uxhumano lwe-dermatitis, ngakolunye uhlangothi, lubangelwa ukusabela kokuchayeka kwamakhemikhali ngqo esikhumbeni. Kubonakala phakathi kweningi labantu kusukela ekusebenzisaneni ne- poison oak (cishe amaphesenti angama-90) futhi kuvamile uma kuvezwa i- nickel , ama-cosmetic agents, nezinwele zoboya . Umuntu namanje kufanele abe namandla amathenda okuthiwa i- T-lymphocytes ukuze aqaphele amakhemikhali njengento yangaphandle futhi asebenze kuwo ukuze athuthukise ukuxhumana nodokotela.
Ubudala bomuntu obhekene ne-atopic dermatitis kubaluleke kakhulu phakathi kwale mibandela emibili. Iningi labantu abathuthuka i-atopic dermatitis baneminyaka emihlanu noma encane, kuyilapho ukuxhumana nodokotela kungavamile kakhulu ezinganeni ezincane.
Indawo ye-eczema iyisici esibaluleke kakhulu uma uhlukanisa phakathi kwe-atopic noxhumana nodokotela.
I-apium dermatitis ngokuvamile ihilela izindawo eziguquguqukayo zesikhumba, njengezimpande zezintambo (antecubital fossa), ngemuva kwamadolo (popliteal fossa), phambi kwentamo, amahlombe ezinsikeni, izinsikazi, futhi ngemuva kwezindlebe.
Izindawo ze-flexural zivame ukuhileleka kubantwana abadala nakubantu abadala ngoba lezi zindawo zilula ukuqala. Njengoba i-atopic dermatitis iyinhlanhla, ukuthi lapho ihlungiwe, ibangela ukuqhuma, kunengqondo ukuthi izindawo ezilula ukuqala kuzoba yizindawo ezakha ukuqhuma. Ngakolunye uhlangothi, uxhumano lwe-dermatitis lwenzeka esakhiweni sokuchayeka kwamakhemikhali, ngakho-ke kungaba khona noma kuphi emzimbeni.
Ukuxilongwa
Ukuxilongwa kwe-dermatitis ye-atopic kuhilela ukutholakala kwe-eczema, ukutholakala kokushaywa (pruritus) , nokutholakala kwemithi. Ukutholakala kwamagciwane kutholakala ukuthi kusetshenziswa ukuhlolwa kwesilonda noma ukuhlolwa kwegazi, ngakho-ke i-atopic dermatitis iyingozi yokugula.
Ukuxilongwa kwe-contact dermatitis kuhilela ukuba khona kwe-eczema, okuvame ukuba yinkinga, kanye nekhono lokunquma ukuqala ngokusetshenziswa kokuhlolwa kwe- patch . Uxhumano lwe-dermatitis alubangelwa inqubo yokwelapha, kepha ngenxa yomphumela wokuxilisa uhlobo lwe-T-lymphocyte eliphuthumayo.
Kungakhathaliseki ukuthi i-eczema ivela ku-atopic dermatitis noma uxhumano lwe-dermatitis, ukuhlonza nokugwema imbangela uma imodi yokwelashwa eyinhloko.
> Imithombo:
> Atopic Dermatitis Practice Parameters. Ann Ukuzivocavoca Isifo Somoya Immunol; 93: S1-21.
> Beltrani VS, Bernstein IL, Cohen DE, Fonacier L. Ukuxhumana ne-Dermatitis: I-Parameter Yokusebenza. Ann Ukuzivocavoca Isifo Somoya Immunol; 97: S1-38.