Izinkinga Nge-Gait, Ukulinganisa Ngokweqile, Ezinye Izimpawu Ezivamile
Izimpawu ze-gluten ataxia, isimo sezinzwa ezibangelwa ukusabela kwiprotheni ye-gluten , singabhekana nobunzima obunzima bokuqhubeka nokungaqiniseki ezinyaweni zakho ezinkingeni zokugwinya. Ungase ube nombono ophindwe kabili, noma ngisho nezindaba ezilawula isisindo sakho.
Izimpawu zakho zingase zivele kancane noma zingase zivele ngokuzumayo, kodwa cishe ngeke zibandakanye izimpawu zokugaya okungabonisa isifo se-celiac .
Abacwaningi baqala ukuchaza i- ataxia ye-gluten , futhi akuwona wonke odokotela abavamile abavuma ukuthi kuyisifo esitholakalisiwe. Ngaphezu kwalokho, azikho izivivinyo zezokwelapha ezitholakalayo ukuze zihlolwe i-gluten ataxia, nakuba abacwaningi abaphezulu emkhakheni wezifo ze-celiac nokungazweli kwe- gluten okungewona we-celiac baye bahlongoza inqubo yokuthola abantu abasolwa ukuthi banalo.
Noma kunjalo, izifundo ezihlukahlukene zezokwelapha ziye zachaza izimpawu ze-acute gliten, futhi ziye zacabangela ukuthi bangaki abantu abangaba ne-gluten ataxia .
Izimpawu ze-Gluten ze-Ataxia zifaka phakathi izinkinga zezinkinga, ukungaqiniseki
Izimpawu ze-ataxia ye-gluten zifana nezolunye uhlobo lwe-ataxia, okwenze kube nzima kakhulu ukuhlinzeka ngokuxilongwa okufanele. Iziguli ze-gluten ataxia ngokuvamile zisekupheleni kweminyaka engu-40 noma eminyakeni engama-50 lapho kutholakala khona, nakuba izincwadi zezokwelapha zikhomba amacala amaningana lapho isimo sikhula ezinganeni ezincane noma ezincane. Abesilisa nabesifazane bafanelelwa ngokulinganayo (ngokungafani nesifo se-celiac, lapho abesifazane bengaphezu kwamadoda ).
Ezimweni eziningi, abantu baqaphela izinkinga ngamakhono abo amakhulu okuqala-ngamanye amazwi, bazobe behlushwa kakhulu, bazohamba ngokungahambisani nokuthambekela kokukhubeka noma ukwenza izinto ezimbi, futhi ngokuvamile bayobe bengaboni kahle.
Abantu abane-Gluten ataxia bangase babone nezinkinga ngamakhono amakhono amakhono-isibonelo, umuntu onesimo angase angakwazi ukuchofoza kalula ihembe noma asebenzise ipeni ukuze abhale isikhathi eside.
Ezinye iziguli nazo zishaya amazwi noma zinezinkinga zokukhuluma, kanti abanye banenkinga yokugwinya.
Ukuthola Izinkinga Ziza Okokuqala
Ucwaningo lwezokwelapha lubika ukuthi wonke umuntu one-gluten ataxia unempawu zokuthola i-ataitia, futhi ukuthi lezi zinkinga zivame ukuhambisana nezibonakaliso ezihlobene ne- gluten eziphathelene ne-neuropathy (okungukuthi, ukuxosha emaphethelweni akho). Cishe u-80% unezinkinga ngamehlo abo, lapho amehlo abo ahamba khona ngokungahambi emuva.
Cishe amaphesenti angama-60% abonisa ubufakazi balokho okubizwa ngokuthi "inzwa ye-axonal neuropathy," okusho ukulimala kwamagciwane okubangela ukuzwa kokukhipha, ukulahlekelwa kwesisindo ngisho nobuhlungu emaphethelweni. Kodwa-ke, lezi zimpawu ngokuvamile ziba mnene, futhi azibandakanyi kakhulu ku-ataxia, abacwaningi bathi.
Naphezu kwezinto ezibangelwa i-gluten yomonakalo emizimbeni yazo, abantu abangaba ngu-10 kuphela abane-gluten ataxia bazoba nezimpawu zamathumbu ezifana nokuhuda, ukuqothulwa , ukubhuka, ubuhlungu besisu, igesi kanye ne- reflux . Naphezu kwalesi sibonakaliso sezinga eliphansi, isifundo esisodwa sathola ukuthi iziguli ezingama-24% ze-gluten acaxia empeleni zine- atrophy ehlaselwa yizifo ze-celiac.
Izimpawu Cabanga Ukulimala Kubuchopho Bakho
Zonke lezi zimpawu ze-gluten ze-ayxia zivela emonakalweni ku-cerebellum yakho, ingxenye yengqondo yakho ekhokhiswe ngokuqinisekisa ukuthi imisipha yakho isebenza emakhonsathini omunye nomunye.
Eqinisweni, iziguli ezingu-60% ezihlolwe nge-gluten ataxia zifakazela ukuthi i-cerebellar i-atrophy-literally, i-shrinkage yaleyo ngxenye yobuchopho bayo-lapho ihlolwe yi-imagery magnetic resonance (MRI). Iziguli ezingenayo ukubonakala kwezinto ezibonakalayo ezinqolobaneni zazo zisaqhubeka zibonisa ukungavamile kwezifundo zezokwelapha ezibucayi kakhulu, ngokusho kwabacwaningi.
Lesi sifo sivame ukuqhubeka kancane, kodwa kungenzeka ukuba sisheshe sisheshe siphumelele futhi sine-cerebellar atrophy esathuthuka phakathi nonyaka wezimpawu zokuqala, ngokusho kukaDkt. Marios Hadjivassiliou, isazi sezinzwa ze-UK nomcwaningi ophezulu kule insimu ye-ataxia ye-gluten.
Ucwaningo olwenziwe uDkt. Hadjivassiliou olubheke kweziguli ezingama-68 ezine-gluten ataxia luthi 78% kulabo bantu babethwele eyodwa noma zombili izifo zengculazi eziyinhloko ze- celiac , i- HLA-DQ2 ne- HLA-DQ8 . Isisele saleso qembu sathatha i-HLA-DQ1, okuyiDkt. Hadjivassiliou eye icacile ukuthi ihilelekile ezimpawu ze-neurological ezivela ekungeneni kwe-gluten .
Izwi kusuka
Ekhasini elishicilelwe encwadini ye- BMC Medicine , uDkt. Hadjivassiliou nabanye abacwaningi abaphezulu baphakamise izimpawu ezivame kakhulu ze-acuthenysi ye-gluten futhi bahlongoza i-algorithm yokuxilonga eyenzelwe ukuhlukanisa isimo nesinye isimo se- gluten- nekolweni: isifo se-celiac, gluten ukuzwela , i- dermatitis herpetiformis kanye nokwehluleka ukolweni.
Kodwa-ke, ucwaningo oluningi nokuvumelana kuzodingeka ngaphambi kokuba odokotela babamukele ngokugcwele i-gluten ataxia njengendlela yokuxilongwa, futhi bahlole abantu njalo uma bebonisa izimpawu.
Uma ukholelwa ukuthi ungase ube nezibonakaliso ze-ataxia ye-gluten, kufanele uqale ukhulume nodokotela wakho mayelana nesimo nalokho okuhlangenwe nakho kwakho. Ezinye izimo eziningi, kuhlanganise nezinye izinhlobo ze-ataxia, zingaveza izimpawu ezifanayo. Futhi, akufanele uqale ukudla okungekho gluten ngaphambi kokukhuluma nodokotela wakho, ngoba ukususa i-gluten kungenza imiphumela yakho yokuhlolwa yesifo se-celiac ingalungile.
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