Ukuvimbela Ukulimala Okuhlangene Ingabe Injongo Yokwelapha
Eminyakeni eminingi edlule, indlela yokuthola ukwelapha isifo sokudla kwamathambo kwakujwayelekile. Emuva ngaleso sikhathi, kancane kuningi. Kodwa-ke, phakathi neminyaka, le ndlela isuke isuka ekuziphenduleleni kuya emlonyeni. Kodwa, kungani kushintshwa?
Ukubaluleka Kokuqala Kwamanje, Ukwelashwa Okumangalisayo
Ukuxilongwa kokuqala kwe-arthritis ye-rheumatoid kubonakala kubalulekile ngoba ukwelashwa kokuqala nge- DMARD kanye ne- biologics inikeza ithuba elihle lokuvimbela umonakalo ohlanganyelwe, nokunciphisa ubungozi bokukhubazeka nokufa okuhlobene nalesi sifo.
Isizathu salendlela yokuhlukumezeka kakhulu ukuthi, esikhathini esidlule, iphesenti elikhulu leziguli ezine-arthritis ye-rheumatoid likhubazekile. Ngenhlanhla, akuzona zonke iziguli ezine-arthritis ye-rheumatoid ezisengozini yokulimala okukhulu nokukhubazeka.
Kulabo abanezifo ezincane, ukwelashwa okunonya kungase kungadingeki ukuthi kuqalwe. Kodwa-ke, ngenkathi ama-NSAID (izidakamizwa ezingavimba ukuvuvukala) zingasiza izimpawu zesifo samathambo e-rheumatoid, akukho okusikisela ukuthi basize ukuvimbela umonakalo ohlangene.
Bambalwa, uma kunjalo, iziguli ezine-arthritis ye-rheumatoid zikhethwa ukwelashwa nama-NSAID kuphela. Ngokujwayelekile, iziguli ezinengozini encane yokulimala okuhlangene ziphathwa ngemithi endala ye-DMARD ecatshangwa ukuthi inamandla okuba nemiphumela emibi, kufaka phakathi:
- I-Plaquenil (i-hydroxychloroquine)
- I-Azulfidine (i- sulfasalazine )
- I-Minocin (i-minocycline) -I- antibiotic eye yabonisa inzuzo ku-arthritis ye-rheumatoid, kodwa i-FDA ayivunyelwe leyo nkomba.
Imithi esetshenziselwa ukuba isifo se-rheumatoid esiyinkimbinkimbi ifaka phakathi okulandelayo (nezinye izidakamizwa ezintsha emgqeni):
- I-Methotrexate (i-Rheumatrex, i-Trexall)
- I-Arava (i-leflunomide)
- I-Imuran (azathioprin)
- I-Xeljanz (tofacitinib)
- Enbrel (etanercept)
- I-Remicade (i-infliximab)
- Huma (adalimumab)
- I-Simponi (i-golimumab)
- I-Cimzia (i-certolizumab pegol)
- I-Actemra (tocilizumab)
- I-Rituxan (rituximab)
- Orencia (abatacept)
Iziguli ezinezifo ezincane zesifo sofuba ezinesifo esiyingozi kakhulu zinezinkinga eziningi noma izinkinga ezingase zibe khona ngemisebenzi yokuphila kwansuku zonke , ukulimala okuhlangene, nokusebenza okuhlangene. Ngenxa yokusetshenziswa okungasetshenziswa isikhathi eside kanye nezindleko eziphansi, ama-rheumatologists amaningi azoqala nge-methotrexate njenge-DMARD yokuqala ezigulini ezethula izibonakaliso ezinomthelela ezinzima. I-Prednisone emazingeni aphansi angase abe nesinye isifo sokuguqula isifo.
Izimpawu Nezibonakaliso Zokulimala Okuhlangene
Ukutholwa kwemitholampilo okungase kubonise ukuthi ingozi eyengeziwe yokulimala okuhlanganyelwe kanye nokukhubazeka okulandelayo kuhlanganisa:
- Ukuvuvukala okuhlangene
- Ukuqina kokusa isikhathi eside
- Ukuqala kwamathambo e-rheumatoid esemncane
- I- anti-CCP ephakeme kakhulu
- Isici esikhulu se-rheumatoid
- Ama-nodules we-rheumatoid
- Iprotheni ephezulu e- C-reactive (CRP) kanye ne-sedimentation rate
- Ukungahleleki kwe-Radiographic (x-ray)
Ngeshwa, akunakwenzeka ukuba njalo ubikezele ukuthi ngubani ozokwenza noma ngeke ahlakulele umonakalo owodwa. Ngenxa yalokho, uma unezibonakaliso noma izimpawu zesifo samathambo, qiniseka ukuthi uxoxisana nodokotela we-rheumatologist ukuthola ukwelashwa okungakuhle kuwe.
Iwindi Yelungelo
Kukhona isikhathi esithile lapho ukwelashwa kwe-rheumatoid arthritis kunomthelela omkhulu ekuthuthukisweni kwesifo.
Okungathi umthelela omkhulu kuzoba ukukhululwa kwe- arthritis ye-rheumatoid noma okungenani umthelela ekuthuthukeni kwesifo okuzobonakala ku-x-ray noma emsebenzini ohlangene. Lokhu kuye kwabizwa ngokuthi "I Window of Opportunity" futhi njengoba abacwaningi bafunde kabanzi, iwindi liye lancipha.
Ukuphuthumiswa kokunakekelwa kokuqala kwe-rheumatoid arthritis sekucacile. Umbono wamuva kakhulu lapho ukwelashwa okunonya kufanele kuqaliswe "ukuqala kungcono."
Ngokuthakazelisayo, ukuzama ukuphoqa lapho iwindi lithuba livuleka futhi livale isiguli ngasinye akuzange kubonakale kuyasiza.
Kodwa, akukho ukuphika ukuthi ukuletha lesi sifo ngaphansi kokulawula kungase kube umgomo ocacile. Lokhu kusho ukuphatha i -arthritis engafaneleki , kwezinye izimo, ngethemba lokumisa ukuqhubekela phambili kwayo ku-arthritis egcwele isifo sofuba.
Imithombo:
Iwindi yezokwelapha zethuba le-rheumatoid arthritis: ingabe livaliwe? I-Karim Raza, u-Andrew Filer. Ama-Annal of the Rheumatic Diseases. Mashi 10, 2015.
Ukuxilongwa Kwe-Arthritis Yasekuqaleni Ye-Rheumatoid. Page 73. I-Arthritis Ye-Rheumatoid: Ukuxilongwa Kwangaphambili Nokunakekelwa. Uhlelo lwesithathu. Cush, Weinblatt, iKavanaugh. I-Professional Communications, Inc.