Iyini Indima Yayo?
Ukuvuvukala kungenye yezimbangela ezivame kakhulu zobuhlungu, kodwa kuhlobene yini nobuhlungu be- fibromyalgia ?
Indima yokuvuvukala kule nkinga bekuyisihloko socwaningo kanye nenkulumo-mpikiswano emashumini eminyaka. Eqinisweni, lesi simo sasibizwa ngokuthi "i-fibrositis," esho ukuthi "ukuvuvukala kwezicubu." Nokho, ngokuhamba kwesikhathi, ukungabikho kokuvuvukala okwenzekile kwaholela emphakathini wezokwelapha ukubona i-fibromyalgia ("ubuhlungu obunama-fibrous-muscle nobuhlungu bomzimba") njengegama elinembile.
Emashumini ambalwa eminyaka kamuva, sibheka ukubukeka kwesibili ukuvuvukala kule nkinga, ngenxa yomzimba okhulayo womsebenzi okuphakamisa ukuthi kungadlala indima, nhlobo. Leli chungechunge lokuphenya lingaholela ekuqondeni kangcono ukugula kanye nezinketho zokwelashwa ezandisiwe.
Kungani Ukudideka?
Odokotela bakholelwa ukuthi i-fibromyalgia ayisona isifo sokuvuvukala ngoba asikho njengesifo esiningi sokuvuvukala. Amajoyina awaveli evulekile noma ashisayo. Izivivinyo ezijwayelekile zamakhwala okuvuvukala, okudalula amazinga aphezulu ezifweni ezifana ne- lupus ne- arthritis , ngokuvamile ziveza amazinga avamile noma aphakanyisiwe kuphela ku-fibromyalgia. Ngo-2012, abacwaningi bacwaninga ama-myopathies okuvuvukala (izimo ezibuhlungu) i-fibromyalgia ebizwa ngokuthi "i-myopathy yamanga."
Ukwengeza, izidakamizwa ezilwa nokuvuvukala-kokubili i-corticosteroids kanye ne- non-steroidal anti-inflammatories (ama-NSAID) -vame ukungasebenzi ekunciphiseni ubuhlungu be-fibromyalgia .
Ngakho-ke ukuphi ukuvuvukala kungena kuphi?
Icala Lokuvuvukala
Eminyakeni yamuva, abacwaningi bafunde okuningi mayelana nendima yokuvuvukala okungenzeka kule nkinga.
Entwasahlobo ka-2017, i- Journal of Pain Research yanyathelisa ucwaningo olwalubheka amaprotheni ahlukene angu-92 awaziwayo ukuthi ahlobene nokuvuvukala.
Abacwaningi bathi "kuyinkimbinkimbi kakhulu ... ukutadisha ukuphrofayelwa kweziguli ze-FM kuze kube yimanje." Babika ubufakazi obubanzi bokuvuvukala. Akukhona lokho kuphela, kodwa ubufakazi bubonisa ukuvuvukala kwisistimu yenzwa yomphakathi (ubuchopho nemisipha yomgogodla) kanye nesistimu.
Lo msebenzi uqinisekisile izifundo zangaphambili ezibonisa ukuthi ama-molecule athile avela kumzimba wokuzivikela omzimba, okuthiwa ama-cytokines , aphezulu kubantu abane-fibromyalgia. Lokho kusekela umbono wokuthi lesi simo sihilela ukuvimbela ukuzivikela komzimba.
Uhlelo lwesimiso esiyisisekelo lunamasosha omzimba, ahluke kuwo wonke umzimba, futhi isifundo sibonisa amazinga aphakeme ama-molecule omzimba okuthiwa i-chemokines, futhi.
Ucwaningo olwenziwa ngo-2010 lukaGenvra Liptan, MD, luveza ukuthi kungaba yindawo elula-yezingqimba ezihlangene ezizungeze izakhiwo zangaphakathi-ezivuthayo kwi-fibromyalgia. Umcwaningi uphetha ngokuthi ukungasebenzi kahle kwe-fascial nokuvuvukala kungaba yilokho okuholela ekwakheni ukwakhiwa okuphakathi , okukholelwa ukuthi kuyisici esiyinhloko salesi sifo.
Ukuzwela okuphakathi kwenzeka uma isimiso senzwa esisemkhatsini siba namandla-sishukumisa futhi siphenduka ngokweqile ekufakweni, kufaka phakathi ubuhlungu nezinye izinto ezitholwe izinzwa zakho, njengokukhanya , umsindo , namafutha .
Kucatshangwa ukuthi okungenani kubangelwe yizibonakaliso ezibuhlungu eziqhubekayo eziqhubhisa ubuchopho nomgogodla.
Ucwaningo olwenziwe ngo-2012 lwe- Neuroimmunomodulation uphenye indima ye-systemic yokuvuvukala kwesistimu kanye nokuphendula ngokucindezeleka ku-fibromyalgia. Abacwaningi bathola ukuthi kunesimo sokuvuvukala esibonakala sengathi siboshwe ekuphenduleni okungavamile kokucindezeleka. Abakwazanga ukucacisa ukuthi ukuvuvukala kwaholela ekucindezeleni ukungasebenzi noma ngokuphambene nalokho.
Ngo-2013, abacwaningi baseSpain abaholwa yi-MD Cordero bashicilela inkolelo yokuthi ukuvuvukala kwe-fibromyalgia kungabangelwa ukungasebenzi emitochondria (izingxenye zamaseli akho adiliza izakhi ukuze enze amandla.) Okunye ukuhlolwa kuka-2010 eSpain, okushicilelwe ku- Clinical Rheumatology , wabonisa amazinga aphakanyisiwe amangqamuzana-okukhulisa amakhemikhali okuvuvukala ekuphenduleni izimbangela ezihlukahlukene-esikhumbeni sabantu abane-fibromyalgia.
Ukuphatha ukuvuvukala ku-Fibromyalgia
Njengoba izindlela zokwelashwa zokuqala zokuvuvukala-i-steroids nama-NSAID-seziboniswa ukuthi aziphumeleli ngokumelene nobuhlungu be-fibromyalgia, yiziphi izinketho esinayo zokunciphisa ukuvuvukala kwethu futhi, ngethemba lokuthi ngenxa yalokho, ubuhlungu bethu?
Ucwaningo luka-2017 luphakamise ukuthi isidakamizwa esibizwa ngokuthi i- low-dose naltrexone (LDN) singasiza ekunciphiseni amamaki athile okuvuvukala, okubonakala esiza ukunciphisa ubuhlungu nezinye izimpawu.
Ucwaningo lwe-Liptan ngo-2010 ngokuvuvukala kwama-fascial kusikisela ukuthi izindlela zokwelapha ezibhekiswe ku-fascia zingase zisebenze. Lokhu kuhlanganisa ukukhululwa kwe-myofascial ( uhlobo lokusikhipha ) kanye nokuxhaphaza okujulile okubizwa ngokuthi i-Rolfing. Kodwa-ke, kuze kube manje, ucwaningo ngalezi zokwelapha lulinganiselwe. Futhi, kuye ngokuthi izimpawu, abanye abantu abanalesi simo bangase bangakwazi ukubekezelela izinhlobo ezithile zokusikhipha.
Ucwaningo olwenziwe ngo-2012 olwanyatheliswa eScandinavia lubonisa ukuthi ukuzivocavoca kwamanzi kungathuthukisa ukulinganisela kwe-cytokine ku-fibromyalgia, ngakho-ke amazinga aphansi okuvuvukala nobuhlungu. (Ngaphambi kokuba uqale noma yiluphi uhlobo lokuzivocavoca, kubalulekile ukufunda ngendlela efanele yokuzivocavoca nge-fibromyalgia .)
Abanye abantu abane-fibromyalgia bathi banenhlanhla ngezingxenye zokudla ezikholelwa ukuthi ukuvuvukala okuphansi. Izithako eziphikisana nokulwa nazo zihlanganisa:
Asingakucwaningi ngokudla okuphikisana nokuvuvukala kwe-fibromyalgia, kodwa odokotela abaningi bayasincoma ngemibandela yokuvuvukala. Ngenxa yokuthi akuzona izimbangela zokuvuvukala wonke umuntu ezifanayo, abantu bavame ukuqala ngokudla okulinganiselwe, bese befaka uhlobo olulodwa lokudla ngesikhathi sokunquma ukuthi yikuphi ukudla okunenkinga.
Izwi kusuka
Njengoba sifunda kabanzi mayelana nendima yokuvuvukala ku-fibromyalgia, cishe singathola izimali ezintsha zezidakamizwa nezinye izifo, futhi lokho kungaholela ekukhetheni okungcono ukwelashwa phansi komgwaqo.
Asazi ukuthi indima yokuvuvukala ingakanani, noma ngabe iyimbangela noma umphumela wesimo. Le mibuzo eningi engaphendulwa njengoba le migqa yophando iyaqhubeka iphhenywe.
Imithombo :,
E-Backryd E, Tanum L, Lind AL, uLarsson A, Gordh T. Journal of ucwaningo ucwaningo. > 2017 Mar 3; 10: 515-525. i-doi: 10.2147 / JPR.S128508. Ubufakazi bokubili ukuvuvukala kwesistimu kanye neuroinflammation kwiziguli ze-fibromyalgia, njengoba kuhlolwe iphaneli lamaprotheni amaningi multiplex lisetshenziselwa uketshezi lwe-cerebrospinal kanye ne-plasma.
UBlanco I, et al. I-rheumatology yemitholampilo. 2010 Dec; 29 (12): 1403-12. Ukugqithisa okungavamile kwama-mastocyte ezigulini zesikhumba zeziguli ze-fibromyalgia.
Bote ME, et al. I-neuroimmunomodulation. 2012; 19 (6): 343-51. Ukuphazamiseka kwengqondo yokuvuvukala / ukucindezeleka kwabesifazane abane-fibromyalgia.
> Cordero MD, et al. Ama-Antioxidants & redox ukusayina. 2013 Mar 1; 18 (7): 800-7. Ingabe ukuvuvukala umcimbi othembeke ekusebenzeni kwe-mitochondrial ku-fibromyalgia?
> Liptan, GL. I-Journal of bodywork kanye nokunyakaza kwemithi. 2010 Jan; 14 (1): 3-12. UFascia: Isixhumanisi esingekho ekuqondeni kwethu nge-pathology ye-fibromyalgia.