I-Isotretinoin (eyayithengiswa ngaphansi kwegama elithi Accutane) ingumuthi oshintshe ukwelashwa kwama- acne . (Amanye amagama egama ahlanganisa: uClavisvis, Amnesteem, ABsorica, Myorisan, Zenatane, noSotret.)
I-Isotretinoin ingokomndeni wemithi ebizwa ngokuthi i-retinoids, efana ne-vitamin A. Isotretinoin, njengezinye i- retinoids , isebenza ngokushintsha ukuqoshwa kwe-DNA.
Lo mphumela wehlisa usayizi nokukhishwa kwezingqungquthela ze- sebaceous . Yenza futhi amangqamuzana ahlanjululwe emigqumeni ye-sebaceous encane encane, ngakho-ke angakwazi ukwenza ama- blackheads namhlophe (ama-comedones). Liphinde linciphise inani lama-bacteria ezigulini ezisabekayo kanye nasesikhumba.
Enye into embi kakhulu emithini yemithi ukuthi ithwala imithwalo yemiphumela emibi kakhulu (kanye nokunye okungathí sina kodwa okwamanje okhathazayo), ngakho qinisekisa ukuthi uhlolisisa ubuhle nobudlova nodokotela wakho ngaphambi kokunquma ukuthi ngabe le mithi ilungile yini ukukhetha ukwelashwa ngawe.
Ubani Othatha Isotretinoin?
I-Isotretinoin ngokuvamile isetshenziselwa i-nodular, i-pustular acne engazange iphendule izifundo ezigcwele zemithi eminingi ye-antibiotic yomlomo. Isimo se-isotretinoin esichaza nge-acne sibheke ekusetshenzisweni ekuqaleni kwenkinga yesifo, ikakhulukazi uma kunesisindo esibalulekile. Ngesikhathi i-isotretinoin isetshenziswa ngokuyinhloko ngama- acne aqinile , isetshenziselwa ezinye izifo ezifana ne-psoriasis, i-lupus, ne- lichen planus ngezinga eliphumelelayo lempumelelo.
Ukuqala Ukwelapha
Kusetshenziselwa izinhlobo eziningana zokulinda, kepha umgomo ovamile uhilela ukuqala ngomthamo ophansi, bese ukwandisa umthamo emva kwamasonto ambalwa. Ubude benkambo yokwelapha buhluka kodwa ngokuvamile buhlala emavikini angu-16 kuya kwangu-20. Abanye abantu bayaqaphela ukuthi i-acne yabo iqala ngokubi kakhulu ngemva kokuqala ukwelashwa kwe-isotretinoin.
Inombolo yezilonda zesikhumba ngokuvamile ayikhuli, kodwa izilonda zingaba zivule noma zibuhlungu kakhulu. Lokhu kuvamile, kuthatha isikhathi esifushane nje, futhi akusona isizathu sokuyeka ukusebenzisa i-isotretinoin.
Izinkinga Zokuzalwa
Imiphumela emibi yalesi sidakamizwa ibe yinsikimba engqubuzanayo. Umphumela ovelele kakhulu, ojulile wukuthi u-teratogenicity. Lokhu kusho ukuthi i-isotretinoin ibangela ukukhubazeka kokuzalwa uma abesifazane besithatha ngenkathi bekhulelwe. Ukukhubazeka okuzalwa okungukuthi izimbangela ze-isotretinoin zihlanganisa uhlelo oluyisisekelo senzwa, ubuso, inhliziyo, kanye ne-thymus gland engavamile. Ngemuva kokwelashwa kwe-isotretinoin sekuphelile inyanga eyodwa, owesifazane angakhulelwa ngaphandle kokukhathazeka ngokukhubazeka kokuzalwa. I-Isotretinoin ayithinti ukuzala noma yenza kube nzima ukukhulelwa. Abesifazane abathatha i-isotretinoin kumele basebenzise izinhlobo ezimbili zokulawulwa kokuzalwa ngalesi sikhathi: inyanga ngaphambi kokunakekelwa ekupheleni kwenyanga yokuqala yokwelashwa.
Imiphumela emibi kakhulu
Ukwelashwa kwe-Isotretinoin kunezimo ezimbi ezilandelayo.
- Izikhwehlela , uma ziphikelela futhi zihambisana nesicanucanu, ukuhlanza, nombono ongenalutho, kungaba uphawu lwesimo esibizwa ngokuthi i-pseudotumor cerebri.
- Ingozi yokucindezeleka, ukucindezeleka kwengqondo nokuzama ukuzibulala kukhula ngesikhathi sokwelashwa futhi kubuyela esimweni esivamile ngemuva kokuyeka umuthi.
- Ukukhiqizwa kwezinyembezi emehlweni kunciphile, okungabangela ubomvu, amehlo abonakalayo kanye nezilonda ezithile ze-cornea, ikakhulukazi nabathwali be- lens .
- Ikhono lokuhlukanisa phakathi kwama-shades omnyama nomhlophe lingancipha, okwenza ubumpumputhe ubusuku.
- Ama-enzyme ye-fover angakhuphuka, okwenza i-jaundice, i-hepatitis, nobuhlungu besisu.
Eminye imiphumela emibi
Ukwelashwa kwe-Isotretinoin kungabangela ukuthi okulandelayo kungathí sina okungathí sina, kodwa imiphumela emibi engase ibe yicala.
- Isikhumba esomile esidinga ukusetshenziswa njalo kwama-moisturizers
- Izindebe ezimile futhi eziqhekezayo
- I-Nosebleeds
- Isikhumba esinamahloni (pruritus)
- Izinwele zokucwenga
- Ukuqhathanisa ngokweqile, ikakhulukazi kwezintende zezandla nezinyawo
- Ama-muscle aches and pain that are worse with activity
- Ukuzwela okwenyuka elangeni, okubangela ukushisa kwelanga kalula
- Amazinga aphakeme we-triglyceride
I-Lab Ukuqapha
Ngaphambi kokuqala ukwelashwa kwe-isotretinoin, iziguli kufanele zenziwe umsebenzi wegazi ukuhlola amazinga we-triglyceride, umsebenzi wesibindi, nokubala kwegazi okuphelele. Abesifazane kufanele futhi bathathe ukuhlolwa kokukhulelwa. Ngezikhathi ezithile, ngenkathi yokwelapha, kodwa ikakhulukazi inyanga eyodwa ngemva kokuqala ukwelashwa, lawa ma-labs ahlolwe futhi.
Ukuqeda Ukwelapha
I-course ejwayelekile yezokwelapha amaviki angu-16 kuya kwangu-20. Ekupheleni kwamasonto angu-16, iziguli ezingaba ngu-85% zicacile. Imiphumela ezuzisayo ye-isotretinoin ayigodli lapho isidakamizwa sikhishwa. Ukunciphisa okunye ukugaya izilonda nokuqeda kubonakala izinyanga emva kokuba ukwelashwa sekuyeke. Omunye umphumela ozuzisayo we-isotretinoin wukuthi ngemva kokuhamba kwezidakamizwa, isikhumba ngokuvamile siphendula kangcono ukwelashwa kwama-acne okuvamile.
Imicabango Yokugcina
Imiphumela emibi ye-isotretinoin therapy iye yavimbela abanye abantu ukuthi bangawubheki njengendlela yokwelashwa okunempilo. Naphezu kwemiphumela yaso emibi, i-isotretinoin ihlala yindlela yokwelapha enamandla kunawo wonke futhi ethembisayo yokwenza ama- acne amancane. Esebenzisa ngendlela ehlakaniphile, ngokuqapha ngokucophelela, kungashintsha ukuphila komuntu osemusha noma omdala osemusha.