I-Lupus yisimo esizimele esingabangela i-pleurisy kodwa sithinteka kwezinye izimo zamaphaphu eziningana. Ziyini izimpawu, zitholwa kanjani, futhi yiziphi izinyathelo ezitholakalayo ze-pleurisy ezihlobene ne-lupus? Iziphi ezinye izifo zamaphaphu ezenzeka ngokuvamile phakathi kwabantu abane-lupus?
I-systemic lupus erythematosus (SLE), isifo esizimele, isifo ngempela sezimpawu.
Ihlasela isimiso somzimba sokuzivikela komzimba futhi singathinta konke esikhumbeni nasemalungeni ezitho zangaphakathi.
I-Lupus iyisifo esivame kakhulu sokuxhuma izicubu ukuze sibe nezimpawu zamaphaphu (amaphaphu). Abantu abaningi abane-lupus bahlakulela izimo zamaphaphu, futhi lokhu kubalulekile ekuchazeni kwesifo.
Lupus noPleurisy
I-Pleurisy (ubuhlungu besifuba se-pleuritic) yiyona ejwayelekile kakhulu ye-pulmonary (lung) ukubonakaliswa kwe-lupus. I-Pleurisy isifo sokuhlonza okuchazayo okubhekisela ebuhlungu esifubeni esenzeka ngesikhathi sokuphefumula (ngezinye izikhathi kuphela ngesikhathi sokuphefumula okujulile noma ngesikhathi sokukhwehlela).
Ukucindezela lokhu kubuhlungu ukuvuvukala kwamagundane amabili afaka amaphaphu (i -pleura ). I-pleura ihlukaniswa ngendwangu encane ebizwa ngokuthi i- pleural cavity , evame ukuqukethe amathisipuni amathathu kuya kwamane we- pleural fluid . Ngokubambisana, i-pleura isenzo njengendlela yokunciphisa, ukunciphisa ukungqubuzana emaphashini lapho uphefumulela ngaphakathi nangaphandle.
With lupus, autoantibodies (antibodies eziqondiswe ezakhiweni zakho siqu) kulona pleura, ukudala ukuvuvukala. Lokhu ukuvuvukala kungabangela ubuhlungu obukwenzeka uma uphefumulela noma uwukhiphe ngaphandle - noma yini edala ukuthi i-pleura ihambe. Ngezinye izikhathi ukuvuvukala komnene futhi kungakhathazeki kwenzeka kuphela ngokuphefumula okujulile, ukukhwehlela, ukugcoba, noma ukuphelelwa yisikhathi.
Ngesinye isikhathi ukuvuvukala kungase kube nzima kakhulu, okuholela ebuhlungu ngisho nokuphefumula okuvamile okuthulile.
Njengenye ingcindezi yale nqubo, ukuvuvukala kungaholela ekwakheni kwamanzi phakathi kwe-pleura. Ukukhishwa kwe-pleural impumuzo kungahlukahluka ezimpawu ezivela kunoma (uma kunomthamo omncane woketshezi oludlulayo okwamanje) ukuphefumula okukhulu nobuhlungu obunzima ngokucindezela okukhulu okunamandla okucindezela amaphaphu.
Ake sibheke ngokucophelela izimpawu, ukuxilongwa, nokwelashwa kwe-pleurisy, kulandelwa ukubuyekezwa okufushane kwezinye izifo zamaphaphu ezingase zihlotshaniswe ne-lupus.
Izimpawu
Izimpawu ze-pleurisy ne-lupus zingabandakanya:
- Ubuhlungu ngokuphefumula, ukukhwehlela, noma ukuhamba kwesifuba (ubuhlungu besifuba se-pleuritic)
- Ubuhlungu ehlombe (ngenxa yokuvuvukala kwemizwa ehlombe elidlula kulolu daba
- Ukuphefumula (lapho kuqhutshwa ukuxoshwa kwenhliziyo, noma ngenxa yokugwema ukuphefumula okujulile ngenxa yokunganaki)
- Isilinganiso sokuphefumula esheshayo
- I- Cyanosis (i-blueness yesikhumba kusuka ekunciphiseni oksijini). I-Cyanosis iyenzeka kuphela uma inani elikhulu lamanzi abizayo
Ukuxilongwa
Ukuxilongwa kwe-pleurisy ehlobene ne-lupus kuvame ukusetshenziswa ngokusebenzisa inhlanganisela yomlando oqaphile kanye nokuhlolwa komzimba, kanye nokuhlolwa kwelebhu kanye nezifundo zokucabanga.
Umlando we-lupus ne-pleuritic-uhlobo lobuhlungu besifuba kungase kube yilokho okudingekayo ukuze kuhlolwe uma izimpawu zincane. I-pleura ibushelelezi, kodwa uma ihlaselwa yi-pleuritis, iba yingozi, ixubana ndawonye, futhi ivame ukukhiqiza umsindo ozwakalayo. Lo msindo uzwakala nge-stethoscope, futhi ngezinye izikhathi ngokumane ubeke indlebe esifubeni.
Njengoba i-lupus ihlotshaniswa nezinye izimo zamapayipi, ezinye izivivinyo zivame ukwenza. Ezinye zazo zingabandakanya:
- Umsebenzi wegazi - Ukuhlolwa kwegazi nge lupus (uma lokhu kungakenziwa kakade)
- Ukubala okuphelele kwegazi - I-CBC ingasiza ukulawula ezinye izimbangela ze-pleurisy njengezifo ezithathelwana nge-bacterial noma virus.
- I-x-ray yesifuba noma i-CT scan.
- Uma ukuxoshwa kwamapulatifomu kukhona, i-thoracentesis ivame ukwenza. Kule nqubo, inaliti enhle ifakwa phakathi kwesifuba singene esikhala sokukhalazela ukuhoxisa uketshezi. Ngaphezu kokunciphisa usayizi we-pleural effusion (uma ukuphefumula okukhona), lokhu kusetshenziselwa ukuhlaziywa ebhodini ukulawula ezinye izimbangela ezibangelwa ukuxuba.
Ukwelapha
Ngokuvamile akulona ukwelashwa okuqondile kwe-pleurisy ehlobene ne-pleurisy ngaphandle kokuthi ukutheleleka kwegciwane noma ukutheleleka ngegciwane kungenxa yokuvuvukala okubangelwa yi-autoimmune. Njengoba isimo esizimele se-lupus sinesibopho sezimpawu isikhathi esiningi, noma yiziphi izindlela zokwelashwa ezisetshenziselwa ukwelapha i-lupus, ngokujwayelekile, zizoqondiswa ku-pleurisy. I-Pleurisy ebangelwa i-lupus kumele iqhube inkambo yayo ngesikhathi, futhi ubuhlungu bungaphathwa ngezidakamizwa ezilwa nokuvuvukala ize ixazulule.
Ezinye Izindlela I-Lupus Engayithinta Ngayo Amapayipi akho
Olunye uhlobo lwesimo sephaphu luthinta abantu abangamaphesenti angu-50 abantu abane-lupus. Kungenza kanjalo ngokuthinta izingxenye eziningi nezakhiwo zamaphaphu kuhlanganise:
- Pleura (njengokungathi ku pleuriy okukhulunywe ngenhla)
- Izicubu zomzimba ngokwazo (izicubu ezixhumene namaphaphu)
- I-Alveoli (ama-sacs air amancane emaphashini aphethwe ukushintshaniswa kwe-oxygen ne-carbon dioxide)
- I-brronchi ne- bronchioles ( imizila emikhulu nemincane yamaphaphu)
- Imikhumbi yegazi emaphashini
- I-Diaphragm (njengokwehla kwe-lung syndrome okukhulunywe ngezansi)
Izimo Eziphathelene Nezokwelapha Ezihlobene Nezilonda Ezihlobene Ne-Lupus
Ngaphezu kwe-pleurisy, kunezinye izifo zamaphaphu ezenzeka ngokuvamile kubantu abane-lupus. Eziningi zalezi zimo zinezimpawu zokukhwehlela, ukuphefumula, futhi ngezinye izikhathi zikhwehlela igazi , ngakho-ke ukuhlolwa ngokucophelela kuyadingeka ukuze kunqume imbangela eqondile. Izimo zomzimba (ngaphezu kwe-pleurisy) ezihlobene ne-lupus zihlanganisa:
- I-Lupus pneumonitis (kokubili elula futhi engapheliyo) - I-Lupus pneumonitis ibhekisela ukuvuvukala kwamathishu emaphaphu. Ngabe kunzima kangakanani kungabangela ukukhwehlela, ukuphefumula, nobuhlungu ngokuphefumula? I-steroids ivame ukusetshenziswa, futhi kungadingeka ukulinganiselwa okuphezulu.
- Umfutho wegazi ophezulu we-pulmonary - I-Pulmonary hypertension yisimo lapho umfutho wegazi ngaphakathi kwe-artery (umthambo ohamba ukusuka e-ventricle efanele yenhliziyo kuya emaphashini) uphakanyisiwe, futhi uvele cishe ngamaphesenti angu-10 abantu abane-lupus.
- Ukwehla kwesifo samaphaphu - Ukulimala nokuvuvukala kwe-diaphragm kungaholela esimweni esibhekwe njengokunciphisa i-lung syndrome. Lesi simo esingavamile sikhombisa ukuphakama kwe-diaphragm, ukuvimbela indawo yamathishu emaphaphu angasetshenziselwa ukushintshaniswa kwegesi.
- Izifo zamaphaphu ezingaphakathi ezifana ne-pulmonary fibrosis - Izifo zomzimba ziyizifo ezithintekayo zamaphaphu (ngokungafani nezimo ezifana ne-asthma kanye ne-emphysema ezivimbela izifo zamaphaphu.) Ukuvuvukala okulandelwa ukulahla kwamapayipi kuvimbela amaphaphu ekukhuleni ngokugcwele ngokuphefumula umsebenzi wemaphaphu.
- Ezinye izimo zamaphaphu - Imibandela efana ne-pulmonary embolism, i-pneumothorax, i-pleural effusion ephindaphindiwe, futhi i-asthma ivame kakhulu kubantu abane-lupus Ngaphezu kwalesi simo, ingozi yomdlavuza wamaphaphu, ikakhulukazi i-squamous cell carcinoma yamaphaphu, iphakeme kubantu abaye bathola ukuthi bane-lupus.
Ngaphansi
Izifo ezinamafutha, njengoba kuphawuliwe, zivamile ne-lupus, ezithinta abangaphezu kwengxenye yabantu abane-lupus ngesikhathi esithile. Isimo esivame kakhulu yi-pleurisy, ukuvuvukala kwezingqimba ezifaka emaphashini ngenxa yenqubo yokuvuvukala esakazeka ku-lupus. Nakuba kungekho ukwelashwa okuqondile, kubalulekile ukuqinisekisa ukuthi esinye sezifo zamaphaphu ngokuvamile esitholakala kubantu abane-lupus akatholakali. Izinyathelo zokunciphisa ubuhlungu, njengemithi, ukulawula ukukhwehlela nokugwema ukuzivocavoca okunzima okuholela ekuphefumuleni okujulile, kungasiza abantu bazizwe bekhululekile kuze kube yilapho lesi sifo siqhubeka.
Imithombo:
Borrell, H., Narvaez, J., Alegre, J. et al. Lalela Funda Kudivayisi kuphela Kwengeziwe Buka Kufakiwe 1 Mahhala Lalela Funda Kudivayisi kuphela Kwengeziwe Buka Kufakiwe Symphony Lung Syndrome Imithi (Baltimore) . 2016. 95 (33): e4626.
Mittoo, S., kanye noC. Ukubonakaliswa kwePulmonary of Systemic Lupus Erythematosis. Ama-Seminar in Medicine Care and Respiratory Care . 2014. 35 (2): 249-54.
Rosenberger, A., Sohns, M., Friedrichs, S. et al. I-Gene-Setha i-Meta-Analysis ye-Cancer Lung ibonisa indlela ehlobene ne-Systemic Lupus Erythematosus. PLoS One . 2017. 12 (3): e0173339.