Ama-Excitotoxins Nalokho Abakwenzayo
Ingabe ukudla okunye kubonakala sengathi kwenza izimpawu zakho ze- fibromyalgia zibi nakakhulu? Kuthiwani ngcono?
Abantu abaningi abanalesi simo babheka izindlela zokudla zokusiza ekunciphiseni izimpawu, futhi ungathola izindaba eziningi ku-intanethi ngabantu abathi baye bathola okuningi ngokudla okungaphezulu kuka-X noma okungaphansi kwe-Y.
Kodwa isayensi yezokwelapha isitshelani ngobuhlobo phakathi kokudla kwethu nezimpawu zethu ?
Kungenzeka okungaphezu kwalokho ocabanga ngakho. Sifunde inani elikhulu eminyakeni yamuva nje engasisiza ukuba sihlele imikhuba yethu yokudla. Okungenani, bangasinika umqondo lapho siqala ukubuka khona.
Into ongase ufune ukuyicabangela ingumphumela wento ethiwa ama-excitotoxins, okufaka ubuchopho bakho engozini. I-excitotoxins eyinhloko i-glutamate ne-aspartate, engangena ekudleni kwakho nge-monosodium glutamate ne-aspartame.
I-Blood Brain Barrier e-Fibromyalgia
Ngaphambi kokubuka i-excitotoxins, kusiza ukuqonda kancane mayelana nobuchopho bakho.
I-Fibromyalgia ibhekwa njengesimo sezinzwa ngenxa yezinto ezingavamile ezaziwayo ohlelweni lwezinzwa eziphakathi, kuhlanganise nokuhlukunyezwa kwezimbangi zamakhemikhali amaningi okuthiwa i- neurotransmitters .
Uma ukhuluma ngomthelela wokudla ngesici sezinzwa zokugula, kufanele ucabangele ukuvinjelwa kwengqondo yegazi (BBB). Umsebenzi we-BBB ukugcina izinto ezivela ebuchosheni ezingafaneleki ukuba khona, noma lokho kufanele zilawulwe yizinhlelo zobuchopho kunokuba zihloselwe ukuthi kwenzekani kuwo wonke umzimba.
Ngokweqile, ukudla odlayo kufanele kube nomthelela omncane ebuchosheni. Nokho, ngenxa yesici esaziwayo se-fibromyalgia, ubuchopho bethu bungaba yingozi kakhulu ekudleni.
Emangqamuzaneni akho, kukhona okuthiwa into P. Umsebenzi walo ukuthumela imilayezo yobuhlungu kusuka kumaseli kuya ebuchosheni bakho.
Abantu abane-fibromyalgia bathole ukuthi banezinto eziphindwe kabili ngaphezu kwezinye izinto P kunabanye abantu.
Futhi nansi into ebalulekile mayelana nempahla P: Ucwaningo lukhombisa ukuthi lwenza ukuthi i-BBB ibe namandla kakhulu, ngakho-ke izinto zingase zenzeke ngokujwayelekile lokho akufanele-futhi akufanele.
I-Monosodium Glutamate ne-Aspartame ku-Fibromyalgia
Kuze kube manje, asinaso ubufakazi obucacile bokuthi noma yikuphi okunye okubi kuwona wonke umuntu onokuthinta i-fibromyalgia. Lokho esikukhoyo ulwazi olukhulayo lwesimo nokuthi izinto ezithile zingase zihlanganyele kanjani nayo.
Ukugxila kokucwaninga okuningi kuye kwaba izithasiselo ezimbalwa zokudla:
- i-monosodium glutamate (MSG)
- i-aspartame
I-MSG yinto ejwayelekile yokudla eyakha ama-flavour. Kuyinto futhi i-amino acid evamile. Igama lesibili egameni layo-glutamate-yinkinga ekhona.
Esikhathini sesistimu sakho sezinzwa, i- glutamate yi-neurotransmitter (isithunywa samakhemikhali). Unomsebenzi obalulekile wama-neuron (ama-brain), okusiza ukugxila futhi ufunde ulwazi olusha. Kodwa-ke, injabulo enkulu yinto embi nge-neurons.
Uma une glutamate kakhulu, izoqhubeka ijabulisa ama-neurons ize iwabulale. Lokhu kwenza ngokwenza ingxenye yeseli ebizwa ngokuthi i-NMDA receptor, okukholelwa ukuthi ihileleke kokubili ubuhlungu nokucindezeleka .
U-Aspartame ungomunye ushukela odayiswa njengeNutriSweet no-Equal, phakathi kwamanye amagama. Uma umzimba wakho uwuqeda, omunye wemikhiqizo oyishiywe yi-aspartate, futhi ivuselela (futhi ingakwazi ukuvuselela ngokweqile) i-NMDA receptor. (I-Aspartate ingxenyana yemvelo yokudla okuningi, futhi akucaci ukuthi ngabe izenzo ze-aspartame ezithathwe ngokuhlukana zihlukile emzimbeni wakho kune-aspartate etholakala kokudla okuvamile.)
Ngenxa yalesi sizathu, i-glutamate ne-aspartame ibizwa ngama-excitotoxins. Ngokungafani namanye amangqamuzana emzimbeni wakho, ama-neurons awashintsheki-umzimba wakho awukwazi ukwenza amasha ukuze athathe labo abafa.
I-Fibromyalgia ikholelwa ukuthi ihlanganisa amazinga aphakeme kunamajwayelekile e-glutamate kwezinye izingxenye zobuchopho.
Kodwa kungenzeka yini ukuthi i-glutamate yokudla kanye ne-aspartate ifaka isandla kulezinga eliphezulu noma yenza kube kubi nakakhulu?
Kumuntu onempilo, i-BBB kufanele igcine lezi zinto zingekho ebuchosheni, kodwa ngeBBB engase ibe yinkimbinkimbi, zingangena kahle.
Ngo-2016, iphephandaba lePain Management lanyathelisa ukubuyekezwa kokucwaninga kwe-fibromyalgia nokudla. Ukubuyekeza kuveza izifundo eziningi ezibonisa ukuxhumana phakathi kwe-glutamate / i-aspartate nobuhlungu kanye nokucwaninga okubonisa amazinga aphezulu e-glutamate ebuchosheni nase-cerebrospinal fluid.
Ucwaningo oluningi luye lwahlola indima ye-glutamate, i-aspartame, namanye ama-excitotoxin ekudleni. Abaningi baye bathola ukuthi ukuwaqeda kwakusiza ukunciphisa izimpawu futhi kubangele ukubuyisela izimpawu ezikhulayo. Abantu abambalwa babonwa ukuthi baye bathola ngokuphelele ngenxa yalolu shintsho lokudla.
Ucwaningo olulodwa, olwanyatheliswa kuRheumatology International, alutholanga ukulungiswa, kodwa abathintekayo baqeda i-MSG kanye ne-aspartame kuphela, okusho ukuthi kungenzeka besadla amanye ama-excitotoxin.
Ukuqeda ama-Excitotoxins
Ukubuyekezwa kokuPhathwa kobuhlungu kusho ukuthi kuphela indlela yokwazi ukuthi unenkinga yama-excitotoxin ekudleni kwakho ukuwaqeda ngokuphelele. Lokhu ngokuvamile kusho ukudla ukudla okuphelele nokugwema noma yini ngezithasiselo.
Buka i-aspartame kunoma imiphi imikhiqizo ebizwa ngokuthi:
- ukudla
- i-sugar-free
- ukunciphisa-ikhalori
I-Aspartame ingase ibe nezindawo ezingacacile, njenge:
- i-yogurt
- okusanhlamvu
- isinkwa
Uma i-MSG ingeziwe ekudleni, kufanele ibalwe njengesithako. Kodwa-ke, i-glutamate ivele ngokwemvelo kokudla okunye, kubandakanya:
- I-soy sauce
- izinhlanzi zezinhlanzi
- I-Worcestershire sauce
- izinkukhu ezindala ezifana ne-cheddar ebukhali ne-parmesan
- i-gelatin
- amaprotheni ase-hydrolyzed
- imvubelo ye-autolyzed
- amaprotheni agxila
- amaprotheni ayodwa
Ezinye izithako ezingase zibe nezinkinga zibandakanya izithako ezingezona ezithize ezingafaka phakathi i-MSG, njenge:
- izinongo
- ukuphumula
- ukunambitheka
- ukunambitheka kwemvelo
Ukubuyekezwa kusikisela kuphela ukusebenzisa ushukela wetafula kuphela noma uju njengama-sweeteners ngenkathi uhlola ukudla okungenamsoco we-excitotoxin. Ithi iningi labafundi abacwaningayo baye babona umehluko endleleni abazizwa ngayo ngemuva kwesonto noma ngaphansi kodwa batusa isikhathi sokuhlola inyanga eyodwa.
Ama-Micronutrients: Ukulwa Ne-Excitotoxins
Amanye ama-micronutrients angavimbela noma anciphise imiphumela yama-excitotoxins. Ukwandisa ekudleni kwakho noma ukuthatha njengezithako kungasiza ekuvimbeleni umonakalo abangakwenza.
Lokhu kufaka:
- i-magnesium
- i-zinc
- i-vitamin B6
- omega-3 fatty acids
- i-vitamin C
- i-vitamin E
- ama-antioxidants afana ne-reservatrol (ngamagilebhisi) kanye nama- polyphenols (itiye elihlaza)
Iningi lalezi zondlo ziye zacutshungulwa nge-fibromyalgia futhi zatholakala ukuthi okungenani ziphumelela ekunciphiseni izimpawu.
Ukuqala isidlo se-Anti-Excitotoxin
Ngaphambi kokuthi ungeze ama-supplement noma uzame ukudliwa kwe-excitotoxin, qiniseka ukuthi ukhuluma nodokotela wakho. Ukuvivinywa kokuntuleka kokudla okunomsoco kungakusiza ukukhomba izithako ezibaluleke kakhulu noma ukudla okungeziwe. Qiniseka ukuthi uxoxe ngezidingo zakho zezempilo kanye nezokudla ukuze ukwazi ukubhekana ngokuphepha nezinguquko ofuna ukuzenza.
Kuze kube yilapho ujwayele ukuthi yikuphi ukudla okwenzayo noma okungaqukatha ama-excitotoxins, kungasiza ukuthi ube nohlu oluphrintiwe noma kudivayisi yakho ehlakaniphile ukuze ukwazi ukuyibheka esitolo. Qinisekisa ukuthi ufundisa noma ubani othenga izitolo noma olungiselela ukudla nawe.
Kunzima ukwazi ukuthi yini oyidlayo endaweni yokudlela, ngakho-ke ungase ufune ukunamathela ekudleni okulungiselelwe ekhaya ngesikhathi sakho sokuhlola.
Khumbula ukuthi izinguquko zokudla azikwazi ukususa zonke izimpawu zakho, futhi kungathatha isikhathi ukubona noma yimiphi imiphumela.
Izwi elivela
Ukudla kokuqeda okunjalo akulula. Kudinga ukuhlela okuningi, ukucabanga, kanye nezinguquko endleleni opheka ngayo. Uma unenkinga yokuhlunguphazeka okungapheli, ukukhathala, nokusebenza okungaqondakali , kungabonakala kungenakunqotshwa.
Zama ukukhumbula ukuthi kuyinkambiso yesikhashana nokuthi ingakusiza uzizwe kangcono ngokuhamba kwesikhathi. Uma kunokwenzeka, thola amalungu omndeni noma abangani ukukusiza ukuze ungabuyeli ukudla okulula ezinsukwini ezimbi.
Futhi uma uphahla futhi udle izinto ongafanele? Ungazishayi phezulu. Cabanga ngethuba lokubona ukuthi lezozinto zokudla zenza uzizwe kanjani, futhi uzame ukuba ngcono ngakho kusasa.
> Imithombo:
> Ciappuccini R, Ansemant T, Maillefert JF, Tavernier C, Ornetti P. I-fibromyalgia eyenziwa yi-Aspartame, imbangela engavamile kodwa ephilisa yokuhlunguphazeka okungapheli. I-rheumatology yemitholampilo nokuhlolwa. 2010 Nov-Dec; 28 (6 Isl. 63): S131-3.
> Holton K. Indima yokudla ekwelapheni i-fibromyalgia. Ukuphathwa kobuhlungu. 2016 Meyi; 6 (4): 317-20. doi: 10.2217 / pmt-2016-0019.
> Holton KF, Karen DL, Thomson CA, uBennett REM, Jones KD. Umphumela we-glutamate wokudla ku-fibromyalgia kanye nezimpawu zamathumbu ezicasulayo. I-rheumatology yemitholampilo nokuhlolwa. 2012 I-Nov-Dec; 30 (6 Isamba 74): 10-7.
> Vellisca MY, uLaterre JI. I-monosodium glutamate ne-aspartame ebuhlungu obubonakalayo e-fibromyalgia. I-Rheumatology international. 2014 Jul; 34 (7): 1011-3. i-doi: 10.1007 / s00296-013-2801-5.