Ukwelashwa Kwezifo Zezifo Ezivuthayo

Ukwelashwa Kwebilini Lesibindi (Influmatory Bowel Disease (IBD)

Izifo zesifo sofuba (IBD) , ezibandakanya isifo sikaCrohn, i-ulcerative colitis, ne-colitis engapheli, izifo ezingapheli zesistimu yokugaya. Kukhona okwamanje akukho ukwelashwa nganoma yiluphi uhlobo lwe-IBD, kodwa kukhona izinketho zokwelapha eziphumelelayo. Lapha sixoxa ngezindlela ezamukelekayo zokwelashwa kwezinhlobo ezimbili eziyinhloko ze-IBD: Isifo sikaCrohn nesifo sofuba esiswini. Iziguli ezine-colitis (okungalinganiselwa ukuthi zihlanganisa amaphesenti angu-10 weziguli ezine-IBD) zihlinzeka ngezikwelapha ezivunywa ukubola kwesilonda.

> Bheka indlela ukulonda kwe-ulcerative kuthinta ngayo ikoloni.

Kunemithi eminingi evunyelwe ukusetshenziswa kubantu abane-Crohn's and ulcerative colitis. Ezinye, kodwa, zivunyelwe kuphela noma enye. Izidakamizwa zinendlela ehlukene yokusebenza nokunikezwa, ngakho-ke iziguli kanye nezidumbu ze-gastroenterologists zingasebenza ndawonye ukuthola okukhethwa kukho okungagcini ngokuphumelelayo izimpawu zabo, kodwa kufanelana nendlela yokuphila yesiguli.

• Uku-Up-to-Date on Vaccinations Kubalulekile Kubantu abane-IBD

• Yiziphi Izingxabano Phakathi Kwalezi 6 Eziphilayo Ze-IBD?

Izindaba ezinhle ukuthi uma imithi eyodwa noma uhlobo olulodwa lwemithi engenzi umsebenzi, kunezinye izidakamizwa ekilasini elifanayo, noma kwelinye iklasi, elingalingwa ngokulandelayo. Ngisho nezindaba ezingcono kakhulu ukuthi kunezinto eziningi zokwelapha ezidalwa ukuphathwa kwe-IBD, futhi kukhona ithemba elikhulu kunanini ngaphambili lokuthola ukwelashwa okusebenza kahle ukuphatha izimpawu ze-IBD nezimbangela ze-IBD zokuvuvukala.

Ukwelashwa kuyindlela yokuphatha i-IBD, futhi kokubili isifo sikaCrohn nesifo sofuba, izinhlobo ezahlukene zokuhlinzwa zisetshenziswa njengokwelapha. Kodwa-ke, uhlobo lokuhlinzwa olusetshenzisiwe luzohluka uma kuncike ekutheni luphathe isifo sikaCrohn noma isifo sofuba esiswini.

Lokhu kungenxa yezindlela ezehlukene lezi zifo ezithinta uhlelo lokugaya nokuthi ukuhlinzwa kuthuthukisa kanjani izimpawu kanye nekhwalithi yokuphila kweziguli. Ngenkathi umcabango wokuhlinzwa uvusa amadlingozi, usetshenziselwa kuphela emva kokunye ukuhlolwa okuye kwavivinywa futhi akusasebenzi.

Izinhloso ze-IBD Treatment

Kukhona imithi eminingi ehlukene esetshenziselwa ukuphatha i-IBD. Lezi imithi ngokuvamile zikhulunywa ngamakilasi, futhi zihlanganisa ama-antibiotics, i-biologics, i-corticosteroids, nama-immunomodulators. Ukwelapha ngemithi kunomgomo ophindwe kabili: ukuthola ukuphazamiseka ngaphansi kokulawulwa nokulahlwa, bese ugcine ukuxoxwa kokuya nokuvimbela ama-flare-ups amaningi. Ezinye izidakamizwa zisetshenziselwa enye yezinhloso noma enye, kanti ezinye zisetshenziselwa kokubili.

Ayikho inqubo eyodwa yokwelapha esetshenziselwa bonke abantu abane-IBD. Kunemihlahlandlela enikezwa izinhlangano zezokwelapha, kodwa ukwelashwa akuyona isayizi eyodwa-kufanelana-konke ukuphakanyiswa. Ukwelashwa kuzodingeka kwenziwe ngokwezifiso ukuze kufane nezidingo zesiguli ngasinye.

Kodwa lokho kusho ukuthi izinqumo mayelana nokukhetha ukwelashwa zisekelwe ebufakazini obuvela ocwaningweni.

Ukwelashwa kwezifo zikaCrohn

Imithi yezifo zika Crohn

Imithi esetshenziselwa ukwelapha isifo sikaCrohn ihlanganisa:

Ama-antibiotics

• I-Cipro (ciprofloxacin)
• I-Flagyl (i-metronidazole)

Ama-immunomodulators

• 6-mercaptopurine (Purinethol, 6-MP)
• I-Azathioprin (Imuran ne-Azasan)
• I-Folex, i-Rheumatrex (methotrexate)
• I-prograf (i-Tacrolimus)
• I-Sandmmune, i-Neoral (i-cyclosporine A)

Corticosteroids

• I-Cortenema (i-hydrocortisone)
• I-Deltasone (i- prednisone )
• Entocort (budesonide)
• I-Medrol (i-methylprednisolone)
• I-Proctofoam-HC (i-hydrocortisone acetate, i-foam rectal)

I-Biologic Therapies

• I-Cimzia (i-certolizumab pegol)
• I-Entyvio (i-vedolizumab)
• Huma (adalimumab)
• I-Inflectra (i-infliximab-dyyb)
• I-Remicade (i-infliximab)
• I-Stelara (ustekinumab)
• I-Tysabri (natalizumab)

Ukuhlinzwa kwezifo zikaCrohn

Ukuhlinzwa ngokujwayelekile kwenziwa ngemva kokuba imithi ingasizi ngokuvuvukala noma kunezinkinga. Uhlobo lokuhlinzwa olwenziwe luzosuselwa endaweni yokuvuvukala kwesifo soCrohn esibangela nokuthi sisakaze kangakanani.

Ukuhlinzwa ngeke kube ukwelashwa kwesifo sikaCrohn futhi, kwabanye abantu, ukuvuvukala kwesifo sikaCrohn kungabuya kwenye indawo.

Ukwelashwa kwesifo sikaCrohn kuhlale kuthuthuka, kanti kwezinye izimo kungenziwa ngamasu amancane (njengalapha laparoscopic ) okwehliswa isikhathi esibhedlela kanye nesikhathi sokutakula. Nazi ezinye ezimbalwa izinhlobo ezijwayelekile zokuhlinzwa ezenziwe ukwelapha isifo sikaCrohn:

• Ukumelana : Uhlobo oluvame kakhulu lohlinzekwa olwenziwe ekwelapheni isifo sikaCrohn yisisombululo. I-resection yilapho ingxenye yesibindi esiphelile noma isifo isuswe, futhi iziphetho ezimbili zezincubu ezinempilo ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde zibuye ziphinde ziphinde ziphinde ziphinde zibuye ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde zibuye zibuye ziphinde ziphinde ziphinde zibuye ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde zibuye ziphinde ziphinde ziphinde zibuye ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde zibuye ziphinde ziphinde zibuye ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde zi Lokhu kungenziwa emathunjini amancane noma emathunjini amakhulu .
• I-Strictureplasty : Isifo sikaCrohn singabangela izicubu ezilalayo ezakhayo futhi zingabangela ukunciphisa emathunjini. Uma ingxenye yamathumbu iba mncane kakhulu, ingase ivuleke futhi ngesikhathi sokuhlinzwa kwe-strictureplasty.
• I-Proctocolectomy : Kwamanye abantu abanesifo sikaCrohn lapho kungekho isifo emgodleni, i-proctocolectomy yokubuyisela ingenziwa. Amathumbu amakhulu asusiwe futhi ukuphela kwamathumbu amancane kuxhunywe ngqo kwi-anus. Lokhu kusho ukuthi i- stoma ayidingi futhi isobho singadluliselwa phansi. Lolu hlobo lokuhlinzeka luvame ukwenza kuphela eqenjini elithile leziguli. Lokhu kuvulwa kubizwa nangokuthi i-anastomosis ye-ileoanal (iqonde ngokukhipha).

• Umhlahlandlela Wakho Wokuthola I-Course Of Prednisone

• Okushiwo Abantu abane-IBD Kufanele Bazi Ngokuphathelene Ne-Cipro

• Ukwelashwa kwe-Ostomy : Abanye abantu abanesifo sikaCrohn esithinta ikoloni bayoba nokuhlinzwa ukuze benze i-ileostomy. Yilapho ikoloni isusiwe futhi i-stoma idalwe esiswini. Isitoreli sidlula ngaphandle komzimba esikhundleni sezansi, futhi uhlelo lwe-ostomy luboshwe esiswini ukuze lubambe. Abantu abaningi abanesifo sikaCrohn ngeke badinge ukuhlinzwa kwe-ostomy.

Ukwelashwa kwe-Ulcerative Colitis

Imithi ye-Ulcerative Colitis

Imithi esetshenziselwa ukwelapha i-ulcerative colitis ihlanganisa:

Aminosalicylates (5-ASA)

• I-Azulfidine (i-sulfasalazine)
• Asacol , Pentasa , Lialda, Apriso , Delzicol (mesalamine)
• I-Canasa (i-mesamine suppositories)
• I-Colazal (i-balsalazide)
• I-Dipentum (olsazine)
• I-Rowasa (i-mesalamine enemas)

Ama-immunomodulators

• 6-mercaptopurine (Purinethol, 6-MP)
• I-Azathioprin (Imuran ne-Azasan)
• I-Sandmmune, i-Neoral (i-cyclosporine A)
• I-Tacrolimus (i-Prograf)

Corticosteroids

• I-Cortenema (i-hydrocortisone enema)
• I-Deltasone (i- prednisone )
• Entocort (budesonide)
• I-Medrol (i-methylprednisolone)
• I-Proctofoam-HC (i-hydrocortisone acetate, i-foam rectal)
• Uceris (budesonide)

I-Biologic Therapies

• I-Entyvio (i-vedolizumab)
• Huma (adalimumab)
• I-Inflectra (i-infliximab-dyyb)
• I-Remicade (i-infliximab)
• I-Simponi (i-golimumab)

Ukuhlinzwa kwe-Ulcerative Colitis

I- Crohn's neColitis Foundation of America ilinganisa ukuthi phakathi kwamaphesenti angu-23 no-45% wezilonda ze-ulcerative colitis zihlinzwa. Izinketho zokuhlinzeka nge-ulcerative colitis zihlanganisa njalo ukususwa kwe-intestine enkulu (colectomy), ngokudalwa kwe-stoma noma isikhwama sangaphakathi sokuqoqa isikhala. Izinketho zokuhlinzwa ze-ulcerative colitis zihlanganisa:

• I-protocolectomy ngokudalwa kwesikhwama se-pelvic : Ngemuva kokuba ikoloni isuswe ukuphatha ukwelashwa kwe-ulcerative, isikhwama sangaphakathi sidalwe ngaphandle kwesigaba sokugcina samathumbu amancane (i-ileum). Ngalesi sikhwama, akukho isikhwama se-ostomy yangaphandle noma i-stoma ngoba isikhwama sisebenza njenge-rectum. Ama-pocket ama-pelvic angenziwa ngezimo ezimbalwa ezihlukene, kodwa okusetshenziswa kakhulu yi-j-poch. Lokhu kuhlinzekwa kubizwa ngokuthi i-leal pouch-anal anastomosis, noma i-IPAA.
• I-protocolectomy ngokudala i-ileostomy : Ngemuva kwe-colectomy, ezinye iziguli ezine-ulcerative colitis zine-ileostomy yokuphela eyakhiwe. I-stoma idalwe esiswini sokuhamba kwesitoreji futhi uhlelo lokusebenza lwe-ostomy lugqoke phezu kwe-stoma. Umqondo wokuba nesifo se-stoma ubonakala ukwesabisa, kodwa iziguli eziningi ezine-ulcerative colitis zinekhwalithi ephakeme yokuphila ngemva kokuhlinzwa kwe-leostomy futhi zenza kahle nge-stoma yazo.

Izwi elivela

Kunezinketho eziningi zokwelapha nezokuhlinzwa ezitholakalayo namuhla ukuphatha isifo sikaCrohn kanye nesifo sofuba esiswini kunanini ngaphambili. Izindlela zokwelashwa ezitholakale eminyakeni yamuva zisebenza kahle, futhi kukhona okunye okufundiswayo.

Ingxenye ebaluleke kakhulu yokuphatha i-IBD ngokuphumelelayo nokuyifinyelela ekuxoxweni iwukubona i-gastroenterologist njalo futhi ukuthatha imithi ngesikhathi. Njengoba izidakamizwa ezihlukahlukene zikhona, iziguli eziningi zingakwazi ukwehlisa ukuvuvukala, ukuvimbela izinkinga, nokuthuthukisa izinga lempilo yazo.

> Imithombo:

> Bhandari BM, Kroser JA. "Izifo Zezifo Ezivuthayo." I-American College of Gastroenterology. Mashi 2010, Mashi 2011. Cleveland Clinic Foundation. 26 Septemba 2013.

> Braegger CP, Nicholls S, Murch SH, Stephens S, MacDonald TT. "I-neorros necrosis factor alpha esitokisini njengomaka wokuvuvuka emathunjini." I-Lancet. 1992; 339: 89.

> Crohns & Colitis Foundation of America. "Ukwelashwa kwe-Crohn's Disease & Ulcerative Colitis." CCFA.org. 31 Aug 2010.

> Terdiman JP, Gruss CB, Heidelbaugh JJ, Sultan S, Falck-Ytter YT, i-AGA Institute Clinical Practice and Quality Management Committee. "Isiqondiso se-American Gastroenterological Association Institute on the Use of Thiopurines, Methotrexate, ne-Anti-TNF-a Biologic Drugs for the Induction and Maintenance of Remission in Inflammatory Illness's." I-Gastro. 2013; 145: 1459-1463.