Kungani I-IgE Ebalulekile Futhi Ithinta Kanjani Isifo Sokuhlushwa?
I-Immunoglobulin E, noma i-IgE, ingumzimba wemvelo emzimbeni odlala indima ebalulekile ekuthuthukiseni i-asthma ye-allergen. Amazinga okwandisa we-IgE angase abe nomphumela uma uvezwa ezimbangela, njenge:
Futhi, amazinga akhudlwana we-IgE angabamba iqhaza kulezi zimpawu ezilandelayo:
Uma uthola izifo ezithile, umzimba wakho ukhulula i-IgE, okubopha izinhlobo zamaseli eziningana, njenge:
Uma i-IgE ibopha nanoma iyiphi yalezi zinqamuzana, ingashukumisa isimiso sakho somzimba sokuzivikela , sibangele ukuthi imimoya yakho ibe mncane futhi igwetshwe, futhi yenza izimpawu zakho ze- asthma zibi nakakhulu.
Ukuhlolwa kwe-IgE
Ngenxa yokuthi i-IgE ingase iphakanyiswe nge- asthma ye-allergen , ukuhlola izinga lakho le-IgE kusiza udokotela wakho ukuthi anikeze ukuthi uzozuza yini ekwelapheni ukuze wehlise izinga lakho le-IgE. Ukuze uhlole izinga lakho le-IgE, udokotela wakho uzokuyala ukuhlolwa kwegazi okulula. Ngenxa yalokho, lolu hlelo luvame kakhulu ukuba lukhuphuke ezinganeni ezine-asthma kusukela iningi le-astmma elikhulile liqala kakhulu ukuba "ukungena ngaphakathi" noma ukungabi nesifo se-asthma.
Uma une-asthma elawulwa kabi, ungase ufune ukukhuluma nodokotela wakho ngokuthola izinga lakho le-IgE ihlolwe. Ungase futhi ufune ukuxoxa ngezindlela ongagwema ngazo izinkinga ze- asthma ezingase zandise amazinga wakho we-IgE.
Futhi, ngenxa yokuthi izinga lakho le-IgE liphakanyisiwe, akuyona into ephazamisayo yokuxilongwa nge-asthma. Noma kunjalo, kwandisa ingozi yokuthola uhlobo oluthile lwesifo sofuzo.
Izimpawu ezibonisa ukuthi imbangela yokugula ihlanganisa amehlo anamehlo, izinambuzane, ukukhipha, ukukhwehlela nokuxubana. Odokotela abaningi ngeke basho ukuthi awunawo ubufakazi bokungalingani ngaphandle kokuthola uhlobo oluthile lokuhlolwa ngumuntu ongenalutho (noma okungenani ukuhlolwa kwesilonda).
Qaphela ukuthi ezinye izifo eziningi zingaholela ezingeni eliphakeme le-IgE, njenge-parasite. I-allergenic bronchopulmonary aspergillosis, i-hypersensitivity enhlobonhlobo yomhlabathi ebizwa ngokuthi i- Aspergillus fumigatus , ne-Churg-Strauss syndrome, uhlobo lwe-vasculitis noma ukuvuvukala kwemithambo yegazi, yizimbangela ezimbili ezingavamile zezinga eliphezulu le-IgE. Ngesinye isikhathi abantu bayoba nezinga eliphakeme ngaphandle kwesizathu sangempela esikhombisayo.
Ukwengeza, izinga eliphakeme le-IgE akuyona inkomba yalokho okungase iholele ekuphefumuleni kwakho kwe-asthma. Uzodinga ukuthola uhlobo oluthile lokuhlolwa kokungezwani komzimba ukuze uqonde ukuthi yini engase ibangele i-asthma yakho.
Ukwelashwa kwe-IgE
Kukhona ukwelashwa okulwa no-IgE okuthiwa yi-Xolair (omalizumab). Ungase uzuze ekwelashweni okulwa no-IgE uma:
- Uneminyaka engaphezu kwengu-12
- Yiba nomthelela ekubhebhethekeni kwesifuba esiqhubekayo
- Ukuhlupheka kusuka emzimbeni wonke unyaka
- Awutholanga ukukhululeka nge-steroids e-inhaled nezinye izifo
- Yiba negazi eliphakeme le-IgE
Uma ungeke ukwazi ukukhokhela imithi noma ungakufanelekeli umshwalense wakho, uhlelo lwezidakamizwa luyokwazi ukunikeza ukuphikiswa okuthile. Kubalulekile futhi ukuthi i-Xolair ayibonakaliswa ekwelapheni i-asthma enzima.
Kumele futhi uqaphele imiphumela emibi ye-Xolair efaka ukuphendula kwe-injection site, ukutheleleka kwegciwane okubandakanya ukutheleleka okuphezulu kokuphefumula, ikhanda lokukhwabanisa, nomphimbo.
Kubuye kube nokukhathazeka mayelana ne-anaphylaxis (ukusabela okunzima okukhulu), ngakho-ke, nakuba ungavamile, kufanele uxoxe ukuthi noma awudingi yini i-epinephrine auto-injector ukuze utholakale ngaso sonke isikhathi.
Kubuye kube nokukhathazeka mayelana nokuxhumana okungenzeka kunomdlavuza ngokusetshenziswa kwe-Xolair. Kodwa-ke, ukubuyekezwa kuka-2014 kweziguli ezithathwa okungenani iminyaka emihlanu akutholakali umehluko emkhakheni wegciwane phakathi kweziguli ze-Xolair nalabo ababengaphathwa nge-Xolair.
Imithombo:
I-National Heart, Lung, ne-Blood Institute. Umbiko wePhaneli Wabachwepheshe 3 (EPR3): Izinkombandlela Zokuthola Ukuhlolwa Nokuphathwa Kwe-Asthma
I-Asthma kanye Nokungezwani Komzimba Foundation of America. Ulwazi lomthengi. Indima ye-IgE E-Asthma Yokuthola I-allergic